- Doll. D.C. and Weiss. R.B. (1985) "Neoplasia and the erythron". Journal of Clinical Oncology 3, 429-446.
- Kyle. R.A. (1975) "Multiple myeloma: review of 869 cases". Mayo Clinical Proceedings 50, 29-40.
- MacLennan, I.C., Drayson, M. and Dunn. J. (1994) "Multiple myeloma". British Medical Journal 308, 1033-1036.
- Means. R.T. and Krantz. S.B. (1992) "Progress in understanding the pathogenesis of the anemia of chronic disease". Blood 80. 1639-1647.
- Merko. F., Bergui, L. Gregoretti. M.G., Ghia. P., Aimo. G., Lindley, I.J. and Caligaris-Cappio, F. (1993) "Cytokines involved in the progression of multiple myeloma", Clinical and Experimental Immunology 92, 27-31.
- Ludwig. H., Fritz, E., Kotzmann. H., Höcker. P., Gisslinger. H. and Barnas. U. (1990) "Erythropoietin treatment of anemia associated with multiple myeloma". New England Journal of Medicine 322. 1693-1699.
- Carton. J.P., Gertz, M.A., Witzig, T.E., Greipp, P.R., Lust. J.A., Schroder, G. and Kyle, R.A. (1995) "Epoetin alfa for the treatment of the anemia of multiple myeloma", Archives of Internal Medicine 155, 2069-2074.
- Silvestris, P., Romito. A., Fanelli, P., Vacca, A. and Dammacco, F. (1995) "Long-term therapy with recombinant human erythropoietin (rHuEPO) in progressing multiple myeloma: in vivo erythropoietic and immunomodulatory effects", Annals of Hematologv 70, 313-318.
- Dammacco. F., Castoldi, G. and Rodjer, S. (2001) "Efficacy of epoetin alfa in the treatment of anaemia of multiple myeloma". British Journal of Haematology 113, 172-179.
- Barlogie. B. and Beck, T. (1993) "Recombinant human erythropoietin and the anemia of multiple myeloma". Stem Cell 11, 88-94.
- Ludwig, H., Fritz. E., Leitgeb, C., Percherstorfer. M., Samonigg, H. and Schuster, J. (1994) "Prediction of response to erythropoictin treatment in chronic anemia of cancer". Blood 84, 1056-1063.
- Varel, B., Casadevall. N., Lacombe, C. and Nayeaux. P. (1990) "Erythropoietin physiology and clinical experience". Seminars in Hematology 27, 25-31.
- Erslev, A. (1991) "Erythropoietin", New England Journal of Medicine 324, 1339-1344.
- Barlogie, B., Smallwood. L., Smith, T. and Alexanian, R. (1989) "High serum levels of lactic dehydrogenase identify a high grade lymphoma-like myeloma". Annals of Internal Medicine 110, 521-525.
- Groux, H., Torpier, G., Monte, D., Mouton, B., Capron, A, and Ameisen. J.C. (1992) "Activation-induced death by apoptosis in CD4 + T cells from human immunodeficiency, virus-infected asymptomatic individuals". Journal of Experimental Medicine 175, 331-340.
- Mountz, J.D., Wu. J., Cheng, J. and Zhou, T. (1994) "Autoimmune disease. A problem of defective apoptosis". Arthritis and Rheumatism 37, 1415 -1420.
- Carson, D.A. and Ribeiro, J.M. (1993) "Apoptosis and diseases", The Lancet 341, 1251-1257.
- Ameisen. J.C. (1994) "Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer", AIDS 8. 1197-1213.
- Hahne, M., Rimoldi, D., Schröter, M., Romero, P., Scherei French. L.E., Schneider. P., Bornard, T., Fontana. A., Cerottini, J. and Tschopp, J. (1996) "Melanoma cell expression of Fas (Apo-I/CD95) ligand: implication for tumor immune escape". Science 274, 1363-1366.
- Saas. P, Walker, PR. Hahne, M. Quiquerez, A.L., Schnur Perrio. G., French. 1.,. Van Meir. E.G., de Tribolet, N. and Dietrich. P.Y. (1997) "Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?", Journal of Clinical investigation 99, 1173-1178.
- O'Connel. J., O'Sullivan, J.K. and Shanahan, F. (1996) 'The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand", Journal of Experimental Medicine 184, 1075-1082.
- Tanaka. M., Suda, T., Haze. K., Nakamura, N., Sato. K., Ki Motoyoshi, K., Miruki, M., Tagawa, S., Ohga, S., Hatake Drummond. A.H. and Nagata, S. (1996) "Fas ligand in human serum". Nature Medicine 2, 317-322.
- Itoh. N., Yonehara, S., lshii. A., Yonehara. M., Mizushima. S., Sameshima. M., Hase. A., Seto, Y. and Nagata. S. (1991) "The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis". Cell 66, 233-243.
- Shima, Y., Nishimoto, N., Ogata, A., Fujii. Y, Yoshizaki, K. and Kishimoto. T. (1995) "Myeloma cells express Fas antigen/APO-1 ICD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis". Blood 85, 757-764.
- Westendorf. I.J., Lammert. J.M. and Jelinek, D.K (1995) "Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines", Blood 85, 3566-3576.
- Villunger. A., Egle, A., Marschitz. I., Kos, M., Bock. G., Ludwig. H., Geley. S., Kofler. R. and Greil. R. (1997) "Constitutive expression of Fas (Apo-l/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance". Blood 90, 12-20.
- Cheng. J., Zhou, T., Liu, C. Shapiro, J.P., Brauer. M.J., Keifer, M.C., Barr. P.J. and Mountz, J.D. (1994) "Protection from Fasmediated apoptosis by a soluble form of the Fas molecule". Science 263, 1759-1762.
- Papoff, G., Cascino. I., Eramo, A., Starace, G., Lynch. D.H. and Ruberti. G. (1996) "An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants prevents cell death in vitm". Journal of Immunology 156, 4622-4630.
- Frassanito. M.A., Silvestris. F., Silvestris, N., Cafforio. P., Camarda. G., Iodice. G. and Dammacco. F. (1998) "Fas/Fas-ligand (Fas-1.)deregulated apoptosis and IL-6 insensitivity in highly malignant myeloma cells". Clinical and Experimental Immunology 114, 179-188.
- Wiley. S.R., Schooley, K., Smolak. P.J., Din. WS., Huang. C.P., Nicholl, J.K., Smith. T.D., Rauch. C. and Smith, C.A. (1995) "Identification and characterization of a new member of the TNF family that induces apoprosis", Immunity 3, 673-682.
- Ashkenazi, A. and Dixit, V.M. (1999) "Apoptosis control by death and decoy receptors". Current Opinion in Cell Biology 11. 255-260.
- Park. J.R. (1996) "Cytokine regulation of apoptosis in hematopoietic precursor cells", Current Opinion in Hematology 3, 191-196.
- De Maria, R.,Testa, U., Lucchetti. L., Zeuner, A., Stassi, G., Pelosi, E., Riccioni. R., Felli. N., Samoggia. P. and Peschle. C. (1999) "Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis", Blood 93, 796-803.
- Zamai. L., Secchiero, P., Pierpaoli, S., Bassini. A., Papa, S., Alnemri. E., Guidotti. L., Vitale. M. and Zauli. G. (2000) "TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis", Blood 95, 3716-3724.
- Loken. M.R., Shah. V.O., Dattilio. K.L. and Civin. C.I. (1987) "Row cytometry analysis of human bone marrow. I: normal erythroid development". Blood 69, 255-263.
- Labbaye. C., Valtieri. M., Barberi. T., Meccia, E., Masella. B., Pelosi. E., Condorelli. G.L., Testa, U. and Peschle. C. (1995) "Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis", Journal of Clinical Investigation 95, 2346-2358.
- Orkin, S.H. (1992) "GATA-binding transcription factors in hematopoictic cells", Blood 80, 575-581.
- Orkin. S.H. and Weiss, M.J. (1999) "Cutting red-cell production". Nature 401, 433-436.
- De Maria, R., Zeuner, A., Eramo. A., Domenichelli. C., Bond. D., Grignani, F. and Srinivasula, S.M. (1999) "Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1". Nature 401, 489-493.
- Pisa. P., Stenke. L., Bernell, P., Hansson. M. and Hast, R. (1990) "Tumor necrosis factor-a and interferon-? in serum of multiple myeloma patients", Anticancer Research 10, 817-820.
- Bataille. R. and Harousseau. J.L. (1997) "Multiple myeloma". New England Journal of Medicine 336, 1657-1664.
- Silvestris, R, Cafforio, P., Tucci. M. and Dammacco. F. (2002) "Negative regulation of erythroblast maturation by Fas-1. ' /TRAlL. highly malignant plasma cells: a major pathogenetic mechanism of anemia in multiple myeloma". Blond. 99, 1305-1313.
- Dai. C. Price, J.O., Brunner, T. and Krantzu. S.B. (1998) "Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon-y to produce erythroid cell apoptosis", Blood 91, 1235-1241.
- Killick. S.B., Cox. C.V., Marsh. J.C.W., Gordon-Smith. E.C. and Gibson. F.M. (2000) "Mechanisms of bone marrow progenitor cell apoptosis in aplastic anemia and the effect of anti-thymocyte globuli: examination of the role of the Fas-Fas-L interaction", British Journal of Haematology 111, 1164-1169.
Anemia in Multiple Myeloma: Role of Deregulated Plasma Cell Apoptosis
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