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Research Article

Regulation of Alloresponses after Bone Marrow Transplantation Using Donor T Cells Expressing a Thymidine Kinase Suicide Gene

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Pages 2011-2016 | Published online: 03 Aug 2009

  • [Line 15260]Murphy, W.J., Kumar, V., Cope, J.C. and Bennett, M. (1990) "An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells". J. lmmunol. 144, 3305-3311.
  • [Line 15291]Martin, P.J. (1993) "Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans". J. Exp. Med. 178, 703-712.
  • [Line 15319]Martin, P.J., Hansen, J.A., Torok-Storb, B., Durnam, D., Przspiorka, D., O'Quigley, J., Sanders, J., Sullivan, K.M., Withersnoon, R.P., Deeg, H.J., Appelbaum, F.R., Stewart, P., Weiden, P., Doney, K., Buckner, C.D., Clift, R., Storb, R. and Thomas, E.D. (1988) "Graft failure in patients receiving T cell depleted HLA-identical allogeneic marrow transplants". Bone Marrow Transplant. 3, 445-456.
  • [Line 15364]Kernan, V. Flomenberg, N. Dupont, B. and O'Reilly, R.J. (1987) "Graft rejection in recipients of T-cell depleted HLA-nonidentical marrow transplants for leukemia". Transplantation 43, 843-847.
  • [Line 15395]Bordignon, C., Keever, C.A., Small, T.N., Flomenborg, N., Dupont, B., O'Reilly, R.J. and Kernan, N.A. (1989) "Graft failure after T-cell depleted human leukocyte antigen identical marrow transplants for leukemia. Il. In vitro analysos of host effector mechanisms". Blood 74, 2237-2243.
  • Burakoff, S.J., Deeg, H.J., Ferrara, J. and Atkinson, K. (1990) Graft-Versus-Host Disease (Marcel Dekker, New York, NY).
  • [Line 15453]Vallera, D.A., Youle, R.J., Neville, D.M. and Kersey, J.H. (1982) "Bone marrow transplantation across major histocompatibility harriers. V. Protection of mice from lethal graft-versus-host disease by pretreatment of donor cells with monoclonal anti-Thy 1.2 coupled to the toxin ricin", J. Exp. Med. 155, 949-954.
  • [Line 15484]Waldmann, H., Polliak, A., Hale, G., Or. R., Cividalli, G., Weiss, L., Weshler, Z., Samuel, S., Manor, D. and Brauthar, C. (1984) "Elimination of graft-versus-host disease by in vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (Campath-1)". Lancet 2, 483-486.
  • [Line 15520]Spretn, J., Schaefer, M., Gao, E.K. and Korngold, R. (1988) "Role of T cell subsets in lethal graft-versus-host disease directed to class 1 versus class Il H-2 differences. I. L3T4+ cells can either augment or retard GVHD elicited by Lyt-2+ cells in class 1-different hosts". J. Exp. Med. 167, 556-569.
  • [Line 15551]Korngold, R. and Sprent, J. (1987) "T cell subsets and graft-versus-host disease". Transplantation 44, 355-389.
  • [Line 15580]Antin, J.H. and Ferrara, J.L.M. (1992) "Cytokine dysregulation and acute graft-versus-host disease", Blood 80, 2964-2968.
  • [Line 15609]Reisner, Y., Kapoor, N., Kirkpatrick, D., Pollack, M.S., Dupont, B., Good, R.A. and O'Reilly, R.J. (1981) "Transplantation for acute leukemia with HLA-A and B nonidentical parental marrow cells fractionated with soybean agglutinin and sheep red blood cells", Lancet 2, 327-331.
  • [Line 15643]Dewilte, T., Hoogenhout, J., DePauw, B., Holdrinet, R., Janssen, J., Wessels, J., Van Daal, W., Hustinx, T. and Haanen, C. (1986) "Depletion of donor lymphocytes by counterflow centrifugation successfully prevents acute graft-versus-host disease in matched allogeneic marrow transplantation", Blood 67, 1302-1308.
  • [Line 15679]Clift, R.A., Buckner, C.D., Appelbaum, F.R., Bryant, E., Bearman, S.I., Petersen, F.B., Fisher, L.D., Anasetti, C., Beatty, P. and Bensinger, W.I. (1991) "Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: A randomized study of two irradiation regimens", Blood 77, 1660-1665.
  • [Line 15716]Tiberghien, P., Reynolds, C.W., Keller, J., Spence, S., Deschaseaux, M., Certoux, J.M., Comassot, E., Murphy, W., Lyons, R., Chiang, Y., Herve, P., Longo, D. and Ruscotti, F.W. (1994) "Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donnr T cell depletion after BMT?", Blood 84, 1333-1341.
  • [Line 15756]Munshi, N.C., Govindarajan, R., Drake, R., Ding, L.M., Iyer, R., Saviors, R., Kornbluth, J., Marcus, S., Chiang, Y., Ennisi, D., Kwak, L., Reynolds, C., Tricot, G. and Barlogic, B. (1997) "Thymidine kinase (TK) gene transduced human lymphocytes can be highly purified, remain fuIIy functional, and are killed efficiently with ganciclovir". Blood 89, 1334-1340.
  • [Line 15797]Bonini, Ch., Ferrari, G., Verzeletti, S., Servida, P., Zappone, E., Ruggieri, L., Ponzoni, M., Russini, S., Mavilio, F., Traversari, C. and Bordignon, C. (1997) "HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia". Science 276, 1719-1724.
  • [Line 15835]Drobyski, W.R., Morse, H.C., Burns, W.H., Casper, J.T. and Sandford, G. (2001) "Protection from lethal murine graft versus host disease without compromise of alloengraftment using transgenic donor T cells expressing 3 thymidine kinase suicide gene", Blood 97, 2506-2513.
  • [Line 15867]Martin, P.J., Rowley, S.D., Anasetti, C., Chauncey, T.R., Gooley, T., Peteresdorf, E.W., van Barik, J.A., Flowers, M.H., Storb, R., Appelbaum, F.R. and Hansen, J.A. (1999) "A phase I-II clinical trial to evaluate removal of CD4 cells and partial depletion of CD8 cells from donor marrow for HLA-mismatched unrelated recipients". Blood 94, 2192-2199.
  • [Line 15905]Lake-Bullock, M.H.V., Bryson, J.S., Jennings, C.D. and Kaplan, A.M. (1997) "Inhibition of graft-versus-host disease: use of T cell-controlled suicide gene", J. lmmunol. 158, 5079-5082.
  • [Line 15936]Cohem, J.L., Boyer, O., Salomon, B., Onclercq, R., Charlotte, F., Bruel, S., Boisserie, G. and Klatzmann, D. (1997) "Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes". Blood 89, 4636-4645.
  • [Line 15971]Papadopoulos, K.B., Carabasi, M.H., Castro-Malaspina, H., Childs, B.H., Mackinnon, S., Boulad, F., Giilio, A.P., Kernan, N.A., Small, T.N., Szaboles, P., Taylor, J., Yahalom, J., Collins, N.H., Bleau, S.A., Black, P.M., Heller, G., O'Reilly, R.J. and Young, J.W. (1998) "T cell depleted allogeneic bone marrow transplantation as postremission therapy for acute myelogenous leukemia: freedom from relapse in the absence of graft-versus-host disease", Blood 91, 1083-1090.
  • [Line 16016]Sondel, P.M., Bozdech, M.J., Trigg, M.E., Hong, R., Finlay, J.L., Kohler, P.C., Longo, W., Hank, J.A., Billing, R., Steeves, R. and Flynn, B. (1985) "Additional immunosuppression allows engraftment following HLA-mismatched T cell depleted bone marrow transplantation for leukemia", Transplant. Proc. 17, 460-461.
  • [Line 16054]Keever, C.A., Small, T.N., Flomenberg, N., Heller, G., Pekle, K., Black, P., Percora, A., Gillio, A., Keman, N.A. and O'Reilly, R.J. (1989) "Immune reconstitution following bone marrow transplantation: comparison of recipients of T cell depleted marrow with recipients of conventional marrow grafts", Blood 73, 1340-1350.
  • [Line 16091]Small, T.N., Avigan, P., Dupont, B., Smith, K., Black, P., Heller, G., Polyak, T. and O'Reilly, R.J. (1997) "Immune reconstitution following T-cell depleted bone marrow transplantation: effect of age and posttransplant graft rejection prophylaxis", Biol. Blood Marrow Transplant, 3, 65-75.
  • [Line 16126]Cohen, J.L., Saron, M., Boyer, O., Thomas-Vaslin, V., Bellier, B., Lejeune, L., Charlotte, F. and Klatzmann, D. (2000) "Preservation of graft versus infection effects after suicide gene therapy for prevention of graft versus host disease", Human Gene Ther. 11, 2473-2481.
  • [Line 16161]Giraft, S., Estey, K., Albitar, M., van Besien, K., Rondon, G., Anderlini, P., O'Brien, S., Khouri, I., Gajewski, J., Mehra, R., Claxton, D., Andersson, B., Beran, M., Przepiorka, D., Koller, C., Kornblau, S., Korbling, M., Keating, M., Kantarjian, H. and Champlin, R. (1997) "Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing gralt-versus-leukemia without myeloablative therapy". Blood 99, 4531-4536.
  • [Line 16208]Slavin, S., Nagler, A., Naparstek, E., Kapelushoik, Y., Aker, M., Cividalli, G., Varadi, G., Kirschhaum, M., Ackerstein, A., Samuel, S., Amar, A., Brauthar, C., Ben-Tal, O., EIdor, A. and Or, R. (1998) "Nomnycloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases". Blood 91, 756-763.

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