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Research Article

Advances in the Treatment of Multiple Myeloma: The Role of Thalidomide

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Pages 291-298 | Published online: 01 Jul 2009

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  • Bellamy, W.T. (2001) "Expression of vascular endothelial growth factor and its receptor in multiple myeloma and other hematopoitetic malignancies", Seminars in Oncology 28, 577-582.
  • Singhal, S., Mehta, J., Desikan, R., Ayers, D., Roberson, P., Eddlemon, P., Munshi, N., Anaissie, E., Wilson, C., Dhodapkar, M., Zeddis, J. and Barlogie, B. (1999) "Antitumor activity of thalidomide in refractory multiple myeloma", New England Journal of Medicine 341, 1565-1571.
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  • Rujkumar, S.V. and Kyle, R.A. (2001) "Thalidomide in the treatment of plasma cell malignancies", Journal of Clinical Oncology 19, 3593-3595.
  • Barlogie, B., Zangari, M, Spencer, T., Fassas, A., Anaissie, E., Badros, A., Cromer, J. and Tricot, G. (2001) "Thalidomide in the management of multiple myeloma", Seminars in Hematology 38, 250-259.
  • Barlogie, B., Spencer, T., Tricot, G., Zeldis, J., Munshi, N., Zangari, M., Badros, A., Toor. A., Shaughnessy, J., Morris, C. and Desikan, R. (2000) "Long term follow-up of 169 patients receiving a phase II trial of single agent thalidomide for advanced and refractory multiple myeloma", Blood 96, 5l4a (Abstract).
  • Zangari, M., Anáissie, E., Barlogie, B., Badros, A., Desikan, R., Gopal, A.V., Morris, C., Toor, A., Siegel, E., Fink, L. and Tricot, G. (2001) "Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotheapy", Blood 98, 1614-1615.
  • Cany, L., Fitoussi, O., Boiron, J.M. and Marit, G. (2002) "Tumor lysis syndrome at the beginning of thalidomide therapy for multiple myeloma", Journal of Clinical Oncology 20, 2212.
  • Barlogie, B., Tricot, G. and Anaissie, E. (2001) "Thalidomide in the management of multiple myeloma", Seminars in Oncology 28. 577-582.
  • Hideshima, T., Chauhan, D., Shima, Y., Raje, N., Davies, F.E., Tai, Y.T., Treon, S.P., Lin, B., Schlossman, R.L., Richardson, P., Muller, G., Stirling, D.I. and Anderson, K.C (2000) "Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy", Blood 96, 2943-2950.
  • Davies, F.E., Raje, N., Hideshima, T., Lentzsch, S., Young, G., Tai, Y.T., Lin, B., Podar, K., Gupta, D., Chauhan, D., Treon, S.P., Richardson, P.G., Schlossman, R.L., Morgan, G.J., Muller, G.W., Stirling, D.I. and Anderson, K.C. (2001) "Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma", Blood 98, 210-216.
  • Anderson, K.C. (2001) "Targeted therapy for multiple myeloma", Seminars in Hematotogy 38, 286-294.
  • Juliusson, G., Celsing, F., Turesson, I., Lenhoff, S., Adriansson, M. and Mulm, C. (2000) "Frequent good partial remissions from thalidomide including best response even in patients with advanced refractory and relapsed myeloma", British Journal of Haematology 109, 89-96.
  • Yakoub-Agha, I., Attal, M., Dumontet, C., Moreau, P., Berthou, C., Lamy, T., Grosbois, B., Dauriac, C., Dorvaux, I., Bay, J.O., Monconduit, M., Harousseau, J.L., Duguet, C. and Facon, T. (2000) "Thalidomide in patients with advanced myeloma: survival prognostic factors", Blood 96, 167a (Abstract).
  • Raza, S.N., Veksler, Y., Sabir, T., Li, Z., Anderson, L. and Jagannath, S. (2000) "Durable response to thalidomide in relapsed/refractory multiple myeloma", Blood 96, 168a (Abstract).
  • Tosi, P., Ronconi, S., Zamagni, E., Cellini, C., Tura, S. and Cavo, M. (2000) "Salvage therapy with thalidomide for patients with advanced relapsed/refractory multiple myeloma", Blood 96, 296b (Abstract).
  • Prince, H.M., Biagi, J.J., Mitchell, P., Mileshkin, L., Seymour, J.F., Januszewicz, E.H., Wolf, M.M. and Westerman, D.A. (2000) "lnterferon-a-2b (IF) can be combined with thalidomide (Thal) in patients with multiple myeloma (MM)", Blood 96, 293b (Abstract).
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  • Rujkumar, S.V., Dispcnzicri, A., Lacy, M., Geyer, S., Iturria, N., Fonseca, R., Hayman, S.R., Lust, J.A., Kyle, R., Greipp, P.R., Gertz, M.A. and Witzig, T.E. (2001) "Response rate and durability of response with thalidomide therapy for relapsed multiple myeloma (MM)", Blood 98, 162a (Abstract).
  • Rajkumar, S.V., Hayman, S.R., Fonseca, R., Dispenzieri, A., Lacy, M.Q., Geyer, S., Wellik, L., Lust, J.A., Kyle, R.A., Greipp, P.R., Gertz, M.A. and Witzig, T.E. (2000) "Thalidomide plus dexamethasone (Thal/Dex) and thalidomide alone (Thai) as first line therapy for newly diagnosed myeloma (MM)", Blood 96, 168a (Abstract).
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  • Palumbo, A., Giaccone, L., Bringhen, S., Cavallo, F., Falco, P., Rus, C., Bertola, A., Pileri, A. and Boccadoro, M. (2001) "Low dose thalidomide and dexamethasone are as effective as oral melphalan and prednisone in refractory and relapsed myeloma patients", Blood 98, 162a (Abstract).
  • Tosi, P., Zamagni, E., Cellini, C., Cangini, D., Tura, S., Baccarani, M and Cavo, M (2001) "Rapid response and early relapse after thalidomide plus dexamethasone salvage therapy in patients with advanced relapsed and refractory multiple myeloma", Blood 98, 163a (Abstract).
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  • Srkalovic, G., Karam, M.A., Trebisky, B.M. and Hussein, M.A. (2000) "Treatment of refractory/relapsed multiple myeloma (MM) with combination of melphalan, thalidomide and decadron (MTD)". Blood 96, 294b (Abstract).
  • Dimopoulos, M., Panayiotidis, P., Grigoraki, V. Poziopoulos, C., Xilouri, I., Kiamouris, C., Tassidou, A., Gika, D., Stefanoudaki, K., Anagnostopoulos, N. and Anagnostou, D. (2001) "Oral hyperfractionated cyclophosphamide and intermittent thalidomide-dexamethasone for previously treated patients with multiple myeloma", Blood 98, 164a (Abstract).
  • Barlogie, B. (2001) "High-dose therapy and innovative approaches to treatment of multiple myeloma", Seminars in Hematology 38(Suppl. 3), 21-27.
  • Alexanian, R., Weber, D.M., Giralt, S. and Delasalle, K.B. (2001) "Consolidation therapy of multiple myeloma with thalidomide-dexamethusone after intensive chemotherapy", Blood 98, 163a (Abstract).
  • Somlo, G., Yamamoto, N., Sarah, C., O'Donnell, M., Snyder, D., Sahebi, F., Kogut, N., Spielberger, R., Molina, A., Parker, P., Popplewell, L., Fung, R., Rodriguez, R., Stein, A., Krishnan, A., Chow, W., Lopez, F. and Forman, S. (2001) "Tandem cycle high-dose melphalan and intravenous busulfan/cytoxan with peripheral blood progenitor cell rescue (PBPC) followed by interferon-a-2 (IF) with or without thalidomide (Thai) for multiple myeloma, High complete response rate and moderate toxicities", Blood 98, 685a (Abstract).
  • Thertulien, R., Barlogie, B., Fassas, A., Eddlemon, P., Zangari, M., Muwalla, F., Morris, C., Anaissie, E., Fox, M. and Tricot, G. (2001) "Hybrid MEL/DT PACE autotransplant regimen for multiple myeloma (MM)-safety and efficacy data in pilot study of 15 patients", Blood 98, 686a (Abstract).
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