37
Views
32
CrossRef citations to date
0
Altmetric
Research Article

High Functional P-glycoprotein Activity is More Often Present in T-cell Acute Lymphoblastic Leukaemic Cells in Adults than in Children

, , , , , , , & show all
Pages 85-95 | Published online: 01 Jul 2009

  • Chessells, J.M., Hall, E., Prentice, H.G., Durrant, J., Bailey, C.C. and Richards, S.M. (1998) "The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL, X and XA compared: a report from the MRC Paediatric and Adult Working Parties'', Leukemia 12. 463-473.
  • Perentesis, J.P. (1997) "Why is age such an important independent prognostic factor in acute lymphoblastic leukemia?", Leukemia 11(Suppl. 4), S4-S7.
  • A Collaborative Study of the Group Francais de Cytogenetique Hematologique (1996) "Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologie findings outcome", Blood 87, 3135-3142.
  • Pui, C.H. and Evans, W.F. (1998) "Acute lymphoblastic leukemia", New England Journal of Medicine 339, 605-615.
  • Hoelzer, D. and Gokbuget, N. (2000) "Recent approaches in acute lymphoblastic Leukemia in adults", Critical Reviews in Oncology/Hematology 36, 49-58.
  • Maung, Z.T.,Reid, M.M., Mutheson, E., Taylor, P.R., Proctor, S.J., and Hall, A.G.(1995) "Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia", British Journal of Haematology 91, 93-100.
  • Styezynski, J., Pieters, R., Huismans, D. R., Schuurhuis,G. J., Wysocki, M, and veerman, A. J. (2000) "In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia", British Journal of haematology 110, 813-818.
  • Cole,S. P., Bhardwaj. G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C., Stewart, A.J., Kurz, E.U., Duncan, A.M, and Deeley, R. G. (1992) "Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line", Science. 258, 1650-1654.
  • Cole,S.P. and Deeley, R. G. (1998) "Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP", Bioessays 20. 931-940.
  • Wuchter, C., Leonid, K., Ruppert, V., Schrappe, M., Buchner, T., Schoch, C., Haferlach, T., Harbott, J., Ratei, R., Dorken, B. and Ludwig, W. D. (2000) "Clinical significance of P-glycoprotein expression and function for response to induction chemotherapy, relapse rate and overall survival in acute leukemia", haematologica 85, 711-721.
  • den Boer, M. L., Pietors, R., Kazemier, K. M., Rottier, M. M., Zwaan, C. M., Kaspers, G. J., Janka-Schaub, G., Henze, G., Creutzig, U., Scheper, R.J, and Veerman, A. J. (1998) "Relationship between major vault protein/lung resistance protein. multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia", Blood 91, 2092-2098.
  • Wattel, E., Lepelley, P., Merlat, A., Sartiaux, C., Bauters, F., Jouet, J. P, and Fenaux, P. (1995) "Expression of the multidrug resistance P glycoprotein in newly diagnosed adult acute lymphoblastic leukemia: absence of correlation with response to treatment", Leukemia 9, 1870-1874.
  • Goasguen, J. E., Dossot, J. M., Fardel, O., Le Mee, F., Le Gall, E., Leblay, R., LePrise, P. Y., Chaperon, J. and Fauchet, R. (1993) "Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications", Blood 81, 2394-2398.
  • Dhooge, C., De Moerloose, B., Laureys. G., Kint, J., Ferster, A., De Bacquer, D., Philippe, J. and Benoit, Y. (1999) "P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: results of a 6-year prospective study", British Journal of Haematology 105, 676-683.
  • Ivy, S. P., Olshefski, R. S., Taylor, B. J., Patel, K. M. and Reaman, G. H. (1996) "Correlation of P-glycoprotein expression and function in childhood acute leukemia: a children's cancer group study", Blood 88, 309-318.
  • Keppler, D., Cui, Y., Konig, J., Leier, I. and Nies, A. (1999) "Export pumps for anionic conjugates encoded by MRP genes", Advances in Enzyme Regulation 39, 237-246.
  • Kool, M., de Haas, M., Scheffer, G. L., Scheper, R. J., van Eijk, M. J., Juijn, J. A., Baas, F. and Borst, P. (1997) "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines", Cancer Research 57, 3537-3547.
  • Kool, M., van der Linden, M., de Haas, M., Scheffer, G. L., de Vree, J.M., Smith, A. J., Jansen, G., Peters, G. J., Ponne, N., Scheper, R. J., Elferink, R. P., Baas, F. and Borst, P. (1999) "MRP3, and oganic anion transporter able to transport anti-cancer drugs", Proceedings of the national Academy of Science of the United Sates of America 96,6914-6919.
  • Renes, J., de Vries, E. G., Nienhuis, E. F., Jansen, P. L. and Muller, M. (1999) "ATP-and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1", British Journal of Pharmacology 126, 681-688.
  • Wijnholds, J., Mol, C. A., van Deemter, L., de Haas, M., Scheffer, G. L., Baas, F., Beijnen, J. H., Scheper, R.J., Hatse, S., De Clercq, E., Balzarini, J. and Borst, p. (2000) "Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs", Proceedings of the National Academy of Sciences of the United States of America 97, 7476-7481.
  • van der Kolk, D. M., de Vries, F. G., koning, J. A., van den Berg, E., Muller, M. and Vellenga, E., (1998) "Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34 + peripheral blood cells", Clinical Cancer Research 4, 1727-1736.
  • Kamps, W.A., Veerman, A.J., van Wering, E.R.,van Weerden, J.F., Slater, R. and Does-van den Berg. A. (2000) "Long-term follow-up of Dutch Childhood Leukemia Study Group (DCLSG) protocols for children with acute lymphoblastic leukemia, 1984-1991", Leukemia 14, 2240-2246.
  • Daenen, S., van Imhoff, G.W., van den Berg, E., de Kam, PJ., Haaxma-Reiche, B., Vellenga, E., Smit, J.W and Halie, R.M. (1988) "Improved outcome of adult acute lymphoblastic leukaemia by moderately intensified chemotherapy which includes a 'pre-induction' course for rapid tumour reduction: preliminary results on 66 patients", British Journal of Haematology 100, 273-282.
  • Leier, L., Jedlitschky, G., Buchholz, U., Cole, S.P., Deeley, R.G. and Keppler, D. (1994) "The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates", Journal of Biological Chemistry 269, 27807-27810.
  • Jones, T.R., Zamboni, R., Belley. M., Champion, E., Charette, L., Ford-Hutchinson, A.W., Frenettie, R., Gauthier, J.Y., Leger, S. and Masson, P. (1989) "Pharmacology of L-660, 711 (MK-571 ): a novel potent and selective leukotriene D4 receptor antagonist", Canadian Journal of Physiology and Pharmacology 67, 17-28.
  • Legrand, O., Simonin, G., Perrot, J.Y., Zittoun, R. and Marie, J.P. (1998) "Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients", Blood 91, 4480-4488.
  • De Moerloose, B., Dhooge, C. and Philippe, J. (1999) "Discordance of P-glycoprotein expression and function in acute leukemia", Advances in Experimental Medicine and Biology 457, 107-118.
  • Broxterman, M.J., Sonneveld, P., Feller, N., Ossenkoppele, GJ., Wahrer, D.C., Eekman, C.A., Schoester, M., Lankelma, J., Pinedo, H.M., Lowenberg, B. and Schuurhuis, GJ. (1996) "Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity", Blood 87, 4809-4816.
  • Jasmin, C., Charpentier, A., Marion, S. and Proctor, SJ. (1991) "Concepts of remission, curability and lineage involvement in relationship to the problems of minimal residual leukaemia", Baillieres Clinical Haematology 4, 599-607.
  • te Boekhorst, P.A., de Leeuw, K., Schoesier, M., Wittebol, S., Nooter, K., Hegemeijer, A., Lowenberg, B. and Sonneveld, P. (1993) "Predominance of functional multidrug resistance (MDR-1) phenotype in CD34 + acute myeloid leukemia cells", Blood 82, 3157-3162.
  • Cascavilla, N., Musto, P., D'Arena, G., Ladogana, S., Matera, R. and Carotenuto, M. (1997) "Adult and childhood acute lymphoblastic leukemia: clinico-biological differences based on CD34 antigen expression", Haematologica 82, 31-37.
  • Page, R.L., Hughes, C.S., Huyan, S., Sagris, J. and Trogdon, M. (2000) "Modulation of P-glycoprotein-mediated doxorubicin resistance in canine cell lines", Anticancer Research 20, 3533-3538.
  • van der Kolk, D.M., de Vries, E.G., van Putten, W.J., Verdonck, L.F., Ossenkoppele, GJ., Verhoef, G.E. and Vellenga, E. (2000) "P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia", Clinical Cancer Research 6, 3205-3214.
  • Legrand, O., Simonin, G., Beauchamp-Nicoud, A., Zittoun, R.and Marie, J.P. (1999) "Simultaneous activity of MRPl and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia", Blood 94, 1046-1056.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.