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Leukemia & Lymphoma Volume 44, 2003 - Issue 3
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Research Article

Activation of Protein Kinase C Enhances TNF-α-induced Differentiation by Preventing Apoptosis via Rapid up-regulation of c-Myc Protein Expression in HL-60 Cells

Shunichi Kumakura Division of Blood Transfusion, Shimane Medical University, Izumo, 693-8501, Japan
,
Hiroto Ishikura Department of Clinical Nursing, Shimane Medical University, Izumo, 693-8501, Japan
,
Yasuhisa Maniwa Third Division of Internal Medicine, Shimane Medical University, Izumo, 693-8501, Japan
,
Shoso Munemasa Third Division of Internal Medicine, Shimane Medical University, Izumo, 693-8501, Japan
,
Hiroto Tsumura Third Division of Internal Medicine, Shimane Medical University, Izumo, 693-8501, Japan
,
Junichi Masuda Division of Blood Transfusion, Shimane Medical University, Izumo, 693-8501, Japan
&
Shotai Kobayashi Third Division of Internal Medicine, Shimane Medical University, Izumo, 693-8501, Japan
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Pages 497-503 | Published online: 01 Jul 2009

  • Ishikura, H., Hori, K. and Bloch, A. (1989) "Differential biologic effects resulting from bimodal binding of recombinant human tumor necrosis factor to myeloid leukemia cells", Blood 73, 419-424.
  • Greenblatt, M.S. and Elias, L. (1992) "The type B receptor for tumor necrosis factor-á mediates DNA fragmentation in HL-60 and U937 cells and differentiation in HL-60 cells", Blood 80, 1339-1346.
  • Kumakura, S., Ishikura, H., Tsumura, H., Iwata, Y., Endo, J. and Kobayashi, S. (1996) "C-Myc and Bcl-2 protein expression during the induction of apoptosis and differentiation in TNF-a-treated HL60 cells", Leak. Lymphoma 23, 383-394.
  • Hsu, H., Shu, H.-B., Pan, M.-G. and Goeddle, D.V. (1996) "TRADDTRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways", Cell 84,299-308.
  • Schwandner, R., Wiegmann, K., Bemardo, K., Kreder, D. and Kränke, M. (1997) 'TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase", J. Biol. Chem. 273, 5916-5922.
  • Kim, MY., Linardic, C., Obeid, L. and Hannun, Y. (1991) "Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor á and ?-interferon", J. Biol. Chem. 266, 484-489.
  • Obeid, L.M., Linardic, C.M., Karolak, L.A. and Hannun, Y.A. (1993) "Programmed cell death induced by ceramide", Science 259, 1769-1771.
  • Dbaibo, G.S., Obeid, L.M. and Hannun, Y.A. (1993) "Tumor necrosis factor-á (TNF-a) signal transduction through ceramide", J. Biol Chem. 268, 17762-17766.
  • Müller, G., Ayoub, M., Storz, P., Rennecke, J., Fabbro, D. and Pfizenmaier, K. (1995) "PKC zeta is a molecular switch in signal transduction of TNF-a, bifunctionally regulated by ceramide and arachidonic acid", EMBO J. 14, 1961-1969.
  • Schütze, S., Nottrott, S., Pfizenmaier, K. and Kränke, M. (1990) "Tumor necrosis factor signal transduction. Cell-type-specific activation and translocation of protein kinase C", J. Biol. Chem. 144, 2604-2608.
  • Schütze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. and Kränke, M. (1992) "TNF activates NF-êB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown", Cell 71, 765-776.
  • Yang, Z., Costanzo, M., Golde, D.M. and Kolesnick, R.N. (1993) "Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor êB translocation in intact HL-60 cells", J. Biol Chem. 268, 20520-20523.
  • Beg, A.A. and Baltimore, D. (1996) "An essential role for NF-êB in preventing TNF-a-induced cell death", Science 274, 782-784.
  • Wang, C.Y., Mayo, M.W. and Baldwin, A.S. (1996) "TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NFêB", Science 274, 784-787.
  • Van Antwerp, D.I., Martin, S.J., Kafri, T., Green, D.R. and Verma, I.M. (1996) "Suppression of TNF-a-induced apoptosis by NF-êB", Science 274, 787-789.
  • McConkey, D.J., Hartzell, P., Jondal, M. and Orrenius, S. (1989) "Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C", J. Biol. Chem. 264, 13399-13402.
  • Jarvis, W.D., Fornari, F.A., Browning, J.L., Gewirtz, D.A., Kolesnick, R.N. and Grant, S. (1994) "Attenuation of ceramideinduced apoptosis by diglyceride in human myeloid leukemia cells", J. Biol Chem. 269, 31685-31692.
  • Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P.C., Coso, O.A., Gutkind, J.S. and Spiegel, S. (1996) "Suppression of ceramidemediated programmed cell death by sphingosine-1-phosphate", Nature 381, 800-803.
  • Ohta, H., Sweeney, E.A., Masamune, A., Yatomi, Y., Hakomori, S. and Igarashi, Y. (1995) "Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol esterinduced differentiation", Cancer Res. 55, 691-697.
  • Sakakura, C., Sweeney, E.A., Shirahara, T., Hakomori, S. and Igarashi, Y. (1996) "Suppression of Bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation", FEBS Lett. 379, 177-180.
  • Kolesnick, R.N. (1989) "Sphingomyelinase action inhibits phorbol ester-induced differentiation of human promyelocytic leukemic (HL-60) cells", J. BM. Chem. 264, 7617-7623.
  • Merrill, Jr., A.H., Sereni, A.M., Stevens, V.L., Hannun, Y.A., Bell, R.M. and Kinkade, Jr., J.M. (1986) "Inhibition of phorbol esterdependent differentiation of human promyelocytic leukemic (HL60) cells by sphinganine and other long-chain bases", J. Biol. Chem. 261, 12610-12615.
  • Heikkila, R., Schwab, G., Wichstrom, E., Loke, S.L., Pluznik, D.H., Watt, R. and Nechers, L.M. (1987) "A c-Myc antisense oligoxynucleotide inhibits entry into S phase but not progress from GO to Gl", Nature 328, 445-449.
  • Evan, G.I., Lewis, G.K., Ramsay, G. and Bishop, J.M. (1985) "Isolation of monoclonal antibodies specific for human c-Myc proto-oncogene product", MoI. CeIl. Biol 5, 3610-3616.
  • Kumakura, S., Ishikura, H., Tsumura, H., Hayashi, H., Endo, I. and Tsunematsu, T. (1994) "c-Myc protein expression during cell cycle phases in differentiating HL-60 cells", Leak. Lymphoma 14, 171-180.
  • Nakamura, H., Oda, T., Hamada, K., Hirano, T., Shimizu, N. and Utiyama, H. (1998) "Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells", J. Biol. Chem. 273, 15345-15351.
  • Ruoslahti, E. and Reed, J.C. (1994) "Anchorage dependence, integrins, and apoptosis", Cell 77, 477-478.
  • Raff, M.C. (1992) "Social controls on cell survival and cell death", Nature 356, 397-400.
  • Tonetti, D.A., Horio, M., Collait, ER. and Huberman, E. (1992) "Protein kinase C â gene expression is associated with susceptibility of human promyelocytic cells to phorbol esterinduced differentiation", Cell Growth Differ. 3, 739-745.
  • Tonetti, D.A., Henning-Chub, C, Yamanishi, D.T. and Huberman, E. (1994) "Protein kinase C-ß is required for macrophage differentiation of human HL-60 leukemia cells", J. Biol. Chem. 269, 23230-23235.
  • Rossi, F., McNagny, M., Smith, G., Frampton, J. and Graf, T. (1996) "Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity", EMBO J. 15, 1894-1901.
  • Woolen, M.W., Scibenhener, M.L. and Soh, Y. (1993) "Expression of protein kinase C isoforms in HL60 cells and phorbol ester resistant HL525 cells", Cytobios 76, 19-29.
  • Weistein, I.B., Borner, C.M., Krauss, R.S., O'Driscoll, K., Choi, P.M., Moritomi, M., Hoshina, S., Hsieh, L.L., Tehou-Wong, K.M., Guadagno, S.N., Ueffing, M. and Guillem, J. (1991) "Pleiotropic effects of protein kinase C and the concept of cartinogenesis as a progressive disorder in signal transduction", In: Bruge, I., Curran, T., Harlow, E. and McCormich, F, eds, Origins of Human Cancer: A Comprehensive Review (Cold Spring Harbor Laboratory Press, New York), p. 113.
  • Ways, D.K., Posekany, K., deVente, I., Garris, T., Chen, J., Hooker, J., Qin, W., Cook, P., Fletcher, D. and Parker, P. (1994) "Overexpression of protein kinase C-zeta stimulates leukemic cell differentiation", Cell Growth Differ. 5, 1195-1203.
  • Solary, E., Bertrand, R. and Pommier, Y. (1993) "Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors", Blood 81, 1359-1368.
  • Watanabe, T., Sariban, E., Mitchell, T. and Kufe, D. (1985) "Human c-myc and N-ras expression during induction of HL-60 cellular differentiation", Biochem. Biophys. Res. Commun. 126,999-1005.
  • Kumakura, S., Ishikura, H., Tsumura, H., Nakashima, A., Sato, Y. and Kobayashi, S. (1998) "Down-regulation of c-myc protein expression in GO/G1 phase of the cell cycle during the induction of differentiation by 1, 25 dihydroxyvitamine D3 in HL-60 cells", Shimane J. Med. Sci. 16, 45-49.
  • Bernstein, S.H., Kharbanda, S.M., Sherman, M.L., Stone, R.M. and Kufe, D.W. (1991) "Inhibition of protein kinase C is associated with a decrease in c-myc expression in human myeloid leukemia cells", FEES Lett. 294, 73-76.
  • Jarvis, W.D., Fomari, Jr., FA., Traylor, R.S., Martin, H.A., Kramer, L.B., Erukulla, R.K., Bittman, R. and Grant, S. (1996) "Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells", J. Biol. Chem. 271 8275-8284
  • Kleuser, B., Cuvillier, O. and Spiegel, S. (1998) "1a, 25dihydroxyvitamin D3 inhibit programmed cell death in HL-60 cells by activation of sphingosine kinase", Cancer Res. 58, 1817-1824.

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