Advanced search
Publication Cover
Leukemia & Lymphoma Volume 44, 2003 - Issue 4
Submit an article Journal homepage
28
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Immunoglobulin Gene Rearrangement Investigations in the Diagnosis of Lymphoid Malignancies from Formaldehyde-fixed Biopsies

M.A. Catherwood Department of Haematology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
,
H.D. Alexander Department of Haematology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
,
D.T. McManus Department of Histopathology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
,
R.J.G. Cuthbert Department of Haematology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
&
T.C.M. Morris Department of Haematology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
Pages 645-648 | Published online: 01 Jul 2009

  • Kofsmeyer, S.J. (1988) "B-lymphoid neoplasms: immunoglobulin genes as molecular determinants of clonality. lineage differentiation, and translocation", Advances in Internal Medicine 33, 1-15.
  • Beishuizen, A., Verhoeven, M.A-J., Mol, E.J., Breit, T.M., WolversTetlero, I.L.M. and van Dongen, J.J.M. (1993) "Detection of immunoglobulin heavy-chain gene rearrangements by Southern blot analysis: recommendations for optimal results". Leukaemia 7, 2045-2053.
  • Lehman, C.M., Sarago, C., Nasim, S., Comerford, J., Karcher, D.S. and Garrett, C.T. (1995) "Comparison of PCR with Southern hybridization for the routine detection of immunoglobulin heavy chain gene rearrangements". American Journal of Clinical Pathology 103, 171-176.
  • Wan, J.H., Trainor, K.J., Brisco, M.J. and Morley, A.A. (1990) "Monoclonality in B cell lymphoma detected in paraffin wax embedded sections using the polymerase chain reaction", Journal of Clinical Pathology 43, 888 890.
  • McCarthy, K.P., Sloane, J.P. and Wiedcmann, C.M. (1990) "Rapid method for distinguishing clonal from polyclonal B cell populations in surgical biopsy specimens". Journal of Clinical Pathalogy 43. 429-432.
  • Diss, T.C. (1997) "Polytnerase chain reaction in the assessment of Iymphomas", Cancer Survival 30, 21-44.
  • Deane, M. and Norton, J.D. (1991) "Immunoglobulin gene fingerprinting: an approach to the analysis of B lymphoid clonality in lymphoproliferative disorders", British Journal of Haematology 77, 274-281.
  • Kuppers, R., Willenbroek, K., Rajewsky, K. and Hansnuum, M.L. (1995) "Detection of clonal lambda light chain rearrangements in frozen and paraffin-embedded tissues by polymerase chain reaction". American Journal of Pathology 147, 806-814.
  • Gong, J.K., Zheng, S., Chiarle, R., De Wolf-Peelers, C., Palestro, G., Frizzera, G. and Inghirami, G. (1999) "Detection of immunoglobulin kappa light chain rearrangements by polymerase chain reaction. An improved method for detecting clonal B-cell lymphoproliferative disorders", American Journal of Pathology 155, 355-363.
  • Jackson, D.P., Lewis, H.A., Taylor, G.R., Boylston, A.W. and Quirke, P. (1990) "Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction". Journal of Clinical Pathology 43, 499-504.
  • Ramasamy, I., Brisco, M. and Morley, A. (1992) "Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms". Journal of Clinical Pathology 45, 770-775.
  • Diss, T.C., Liu, H.X., Du, M.Q. and lsaacson, P.G. (2002) "Improvements to B cell clonality analysis using PCR amplification of immunoglobulin light chain genes". Journal of Clinical Pathology 55, 98-101.
  • Cawkwell, P. and Quirke, P. (2000) "Direct multiplex amplification of DNA from a formation fixed, paraffin wax embedded tissue section". Journal of Clinical Pathology: Molecular Patholgoy 53 51-52.
  • Aubin, J., Davi, R, Nguyen-Salomon, F., Leboeuf, D., Deben, C. Taher, M., Valensi, K. Canioni, D., Brousse, N. and Vaiet, B. (1995) "Description of a novel FRI IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B-cell malignancies", lsnkarmia 9, 471-479.
  • Albinger-Hegyi, A., Hochreutener, B., Abdou. M-T. Hegyi, I., Dours Zirnerrmann, M.T., Kurrer, M.O., Heitz., P.U. and Zimmermann, D.R. (2002) "High frequency of t (I4;l8)-translocation breakpoints outside of major breakpoint and minor cluster regions in follicular lymphomas. Improved polymcrase chain reaction protocols for their detection". American Journal of Pathology 160, 823-832.
  • Austin, S.J. Best, J., Matthews, P., Morgan. J M., Mills, K.I., Jasani, B. and Burnett, A.K. (2002) "A comparison between polyacrylamide gel electrophoresis (PAGE) and capillary electrophoresis (CE) analysis of PCR products of immunoglobulin heavy chain (IgH) and T cell receptor gamma (TCR-y) gene rearrangements in lymphoproliferative lesions", British Journal of Haematology 117 173.
  • Feddersen, R.M., Martin, D.J and Van Ness, B.G (1990) "The frequency of multiple recombination events occurring at the human Ig kappa I. chain locus". Journal of Immunology 144, 1088- 1093.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.