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Research Article

Expression of the Multidrug Resistance-associated Protein (mrp ) Gene in Chronic Lymphocytic Leukemia

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Pages 153-158 | Published online: 01 Jul 2009

  • Dalton, W.S. (1997) "Mechanism of drug resistance in hematological malignancies", Semin. Hematol. 34 (Suppl. 5), 3-8.
  • Holmes, J.A., Jacobs, A., Carter, G., Whittaker, J.A., Bentley, D.R. and Padua. R.A. (1990) "Is the mdr I gene relevant in chronic lymphocytic leukemia?, Leukemina, 4, 216-221S.
  • Michieli, M., Respadori, D., Damiani, D., Geromin, A., Gallizia, C., Michelutti, A., Fanin, R., Fasola, G., Russo, D., Tazzari, P., Pileri, S., Mallardi, F. and Baccarani, M. (1991) "The expression of the multidrug resistance-associated glycoprotein in B-cell chronic lymphocytic leukaemia", Br. J. Haematol. 77,440-465.
  • Ribrg, V., Massade. L., Faussat, A.M., Dreysus, F., Bayle, c., Gouyette, A. and Marie, J.P. (1996) "Drug resistance mechanisms in chronic lymphocytic leukemia", Leukemia 10, 1944-1949.
  • Sonneveld, E., Nooter, K., Burghouts, J.Th.M., Herweijier, H., Adriaansen, H.J. and van Dongen, J.J.M. (1992) "High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia', Blood 79,1496-1500.
  • Wallner, J., Gissl nger, H., Gsur, A., Gotzl. M., Zochbauer, S. and Pirker, R. (1994) "MDRI gene expression in chronic lymphocytic leukaemia", Leukemia & Lymphoma 13,333-338.
  • Cole, S.P., Bhardwaj, G., Gerlach, J.H., Mackie, L.E., Grant, C.E., Almquist, K. C., Stewart, A.J., Kurz, E.U., Duncan, A.M. and Deeley, R. G. (1992) "Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line", Science 258, 1560-1564.
  • Krishnamachary, N., Center. M.S. and The, M.R.P. (1993) "Gene associated with a non-P-glycoprotein multidrug resistance encodes a 190kDa membrane bound glycoprotein", Cancer Res. 53,3658-3661.
  • Barrand, M.A., Heppel-Parton, A. C., Wright, K.A., Rabbits, H. and Twentyman, P.R. (1994) "A 190kilodalton protein overxpressedin non-P-glycoprotein-containing multidrug resistant cells and its relationship to MRP gene", J. Natl. Cancer Ist. 86, 110-117.
  • Slovak, M.L., Pelkey, H., Bhardwaj, G., Kurz, E.U., Deeley, R.G. and Cole, S.P.C. (1993) "Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines". Cancer REs. 53, 3321-3325.
  • Zaman, G.J.R., Versantvoort, C.H.M., Smith, J. J. M., Eijmdems, E.W.H.M., De Hass, E.G.E., bass, F and Borst, P. (1993) "Analysis of the expression of MRP, the gene coding for a new putative transmembrane drug efflux transporter, in human multidrug resistant lung cancer cell lines", Cancer Res. 53, 1747-1750.
  • Futsher, B. W., Aobaszadegan, M.R., Domann, F. and Dalton, W.S. (1994) "Analysis of MRP mRNA in mitoxantrone-selected. multidrug-resistant human tumor cells", Biochem. Pharmacol. 47, 1601-1606.
  • Schneider, E., Horton, J. K., Yang, C.H., Nakagawa, M. and Cowam. K. H. (1994) "Multidrug resistance-associated protein gene over-expression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance", Cancer Res. 54, 152-158.
  • Grant, C. E., Valdimarsson, G., Hipfner, D.R., Almquist, K.C., Cole, S.P.c. and Deeley, R. (1994) "Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs", Cancer Res. 54,357-361.
  • Kruh, G.D., Chan, A., Myers, K., Gauhan, K., Miki, T. and Aaronson, S.A. (1994) "Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene", Cancer Res. 54, 1649-1652.
  • Lorico, A., Rappa. G., Flavell, R.A. and Sartorelli, A.C. (1996) "Double Knockout of the MRP gene leads to increased drug sensitivity in vitro", Cancer Res. 56, 5351-5355.
  • Schneider, E., Cowan, K. H., bader, H., Toomey, S., Schwartz, G.N., karp, J.E., Burke, P.J. and Kaufmann, S.H. (1995) "Increased expression of the multidrug resistnce associated protein gene in relapsed acute leukemia", Blood 85, 186-193.
  • Burger, H., Nooter, K., Sonneveld. P., van Wingerden. K.E. and Zaman, G.J.R. (1996) "High expression of the multidrug resistance-associated protein (MRP) in chronic and prolymphocytic leukaemia", Br. J. Haematol. 88,348-356.
  • Burger, H., Nooter, K., Zaman, G.J., Sonneveld, P., Wingerden, K.E., Oostrum, R.G. and Stoter, G. (1994) "Expression of the multidrug resistance-associated protein (MRP) in acute and chronic leukemias", Leukemia 8,990-997.
  • Hart, S.M., Ganeshaguru, K., Hoffbrand, A. V., Prentice, H.G. and Mehta, A.B. (1994) "Expression of the multidrug resistance-associated protein (MRP) in acute leukaemia", Leukemia 8, 2163-2168.
  • Leith, C.P., Kopecky, K.J., Chen, I.M., Eijdems, L., Slovak, M.L., McConnell, T.S., Head, D.R., Weick, J., Grever, M.R., Appelbum, F.R. and Willman, C.L. (1999) "Frequency and clinical significance of the expression of the multidrug resistance proteins MDRI/Pglycoprotein, MRPI, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study", Blood 94, 1086-1099.
  • Kuss, B.J., Deeley, R.G., Cole, S.P., Willman, C.L., Kopecky, K.J., Wolman, S.R., Eyre, H.J., Lane, S.A., Nancarrow, J.K. and Whitmore, S. A. (1994) "Deletion of gene for multidrug resistance in acute myeloid leukaemia with invesrsion in chromosome 16: prognostic implications", Lancet 343,1531-1534/
  • Webb, M., Brun, M., Mc Niven, M., Le Couteur, D. and Craft, P. (1998) "MDRI and MrP expression in chronic B-cell lymphoproliferative disorders", Br. J. Haematol. 102, 710-717.
  • Legrand, O., Perrot, J. V., Tang, R.P., Simonin, G., Gurbuxani, S., Zittoun, R. And Marie, J.P. (1996) "Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone morrow haemopoietic cells", Br. J. Haematol. 94,23-24.
  • Ribrag, V., Massada, L., Faussat, A.M. and Bayle, C. (1996) "Drug resistance mechanisms in chronic lymphocytic leukemia", Leukemia 10,1944-1949.
  • Barrand, M.A., Rhodes, T., Center, M.S. and Twentyman, P.R. (1993) "Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinet from P-glycoprotein", Eur. J. Cancer 29A, 408-415.
  • Solvak, M.L., Pelkey Ho, J., Bhardwaj, G., Kurz, E.U., Deeley, R.G. and cole, S.P.C. (1993) "Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines", Cancer Res. 53,3221-3225.
  • Zaman, G.J., Versantvoort, C.H., Smit, J.J., Eijdems, E.W., de Haas, M., Smith, A.J. and Mulder, N.H. (1993) "Analysis of the expression of the gene for a new putative transmembrane drug transporter in human multidrug resistant lung cancer cell lines", Cancer Res. 53,1747-1750.
  • Nooter, K., Brutel de la Riviere, G., Look, M.P., van Wingerden, K.E., henzen-Logmans, S.C., Scheper, R.J., Flens, M.J., Klijn, J.G., Stoter, G. and Foekens, J.A. (1997) "The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer", Br. J. Cancer 76.486-493.
  • Ito, K., Fujimori. M., Nakata, S., Hama, Y., Shingu, K., Kuwano, H. and Amano, J. (1998) "Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer", Oncol. Res. 10.99-109.
  • Nooter, K., Kok. T., Bosman, F.T., van Wingerden K.E. and Stoter G. (1998) "Expression of the multidrug resistance protein (MRP) in squamous cell carcinome of the oesophagus and response to preoperative chemotherapy", Eur. J. Cancer 34,81-86.
  • Chan, H.S., Lu, Y., Grogan, T.M., Cole, S.P., Deeley, R.G., Ling, V. and Gallie, B.L. (1997) "Multidrug resistnce protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein", Cancer Res. 57,2325-2330.
  • Wang, Q. and Beck, W.T. (1998) "Transcriptional suppression of multidreg resistance associated protein (MRP) gene expression by wild-type p53", Cancer Res. 58, 5762-5769.
  • Sullivan, G.F., Yang, J.M., Vassil, A., Yang, J., Bash-Babula, J. and Hait, W.N. (2000) "Regulation of expression of the multidrug resistance protein MRPI by p53 in human prostate cancer cells", J. Clin. Invest. 105,1261-1267.
  • Fukushima, Y., Oshika, Y., Tokunaga, T., Hatanaka, H., Tomisawa, M., Kawai, K., Ozeki, Y., Tsuchida, T., Kijima, H., Yamazaki, H., Ueyama, Y., Tamaoki, N., Miura, S. and Nakamura, M. (1999) "Multidrug resistance-associated protein (MRP) expression is correlated with expression of abdrrant p53 protein in colorectal cancer", Eur, J. Cancer 35, 935-938.
  • Oshika, Y., Nakamura, M., Tokunaga, T., Fukushima, Y., Abe, Y., Ozeki, Y., Yamazaki, H., Tamaoki, N. and Ueyama, Y. (1998) "Multidrug resistance-associated protein and mutant p53 protein expression in non-small cell lung cancer", Mod pathol. 1, 1059-1063.
  • Gao, Z., Fields, J.Z. and Boman, BM. (1998) "Co-transfection of MDRI and MRP antisense RNAs abolishes the drug resistance in multidrug-resistance human lung cancer cells", Anticancer Res, 18, 3073-3076.

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