24
Views
21
CrossRef citations to date
0
Altmetric
Research Article

Expression of the Multidrug Transporter P-glycoprotein is Highly Correlated with Clinical Outcome in Childhood Acute Lymphoblastic Leukemia: Results of a Long-Term Prospective Study

, , , , , , & show all
Pages 309-314 | Published online: 01 Jul 2009

  • Pui. C.-H. and Evans, W.E. (1998) "Acute Iymphoblastic leukemia", The New England Journal of Medicine 339. 605-615.
  • Chan, H.S.L., Thorner. P.S., Haddad. Deboer, G., Gallie, B and Ling. V. (1995) "Multidrug resistance in malignancies of children", International Journal of Pediatric Hematology/Oncology 2. 11-29.
  • Kartner, N. and Ling, V. (1989) "Multidrug resistance in cancer". Scientific American 260, 44-51.
  • Harrison. D.J. (1995) "Molecular mechanisims of drug resistance in tumours", Journal of Pathology 175, 7-12.
  • Fischer, G.A., Lum, B.L and Hausdorff, J. (1996) "Pharmacological considerations in the modulation of multidrug resistance". European Journal of Cancer 32. 1082-1088.
  • Goasguen, J.E., Dossot, J.-M., Fardel, O., Le Mee. F., Le Gall. E.,Leblay, R., LePrise, P., Chaperon, J. and Fauchet, R. (1993) "Expression of the multidrug resistance-associated P-glycoprotein (P-GP) in 59 cases of de now acute lymphoblastic leukemia: prognostic implications". Blood. 81, 2394-2398.
  • Sauerbrey. A., Zintl, F. and Volm, M. (1994) "P-glycoprotein and glulhalhione-S-transferase II in childhood acute lymphoblastic leukaemia". British Journal of Cancer 70. 1144-1149
  • Dhooge, C., De Moerloose, B., Laurcys, G., Kint, J., Ferster, A., De Bacquer, D., Philippé, J. and Benoil. Y. (1999) "P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: results of a 6-year prospective study". British Journal of Haematolagy 105, 676-683.
  • Gekeler, V., Frese. G., Noller, A., Handgretinger, R., Wiiisch, A. and Schmidt, H. (1992) "Mdrl/P-glycoprotein, topoisomerase. and glutathione-S-transferase II gene expression in primary and relapsed state adult and childhood leukaemias". British Journal of Cancer 66, 507-517.
  • Beck, J., Handgrelinger, R., Dopfer, R., Klingebiel, T., Niethammer, D. and Gekeler, V. (1995) "Expression of mdrl. topoisomerase IIa/ß. and cyclin A in primary or relapsed states of acute lymphoblastic leukaemias". British, Journal of Harmatology 89, 356-363.
  • Ivy, S.P., Olshefski, R.S., Taylor, B.J., Patel, K.M. and Reaman, G.H. (1996) "Correlation of P glycoprolein expression and function in childhood acute leukemia: a children's cancer group study". Blood 88, 309-318.
  • den Boer, M.L., Pieters, R., Kremier, K.M., Roltier, M.M.A., Zwaan. C.M., Kaspers, G.J.L., Janka-Schaub. G., Henze, G.,Creutzig, U., Scheper. R.J. and Veerman, A.J.P. (1998) "Relationship between major vault protein/lung resistance protein. Multidrug resistance-associated protein, P-glycoprotein expression and drug resistance in childhood leukemia". Blood 91. 2092-2098.
  • Langermann, H.J., Henze, G., WuIf, M. and Riehm, H. (1982) "Abschatzung der tumorzellmasse bei der akuten lymphoblastischen leukamie im kindersalter: prognostische hedeutung und praktische anwendung". Klinische Pediatrie 194, 209-213.
  • Dhooge, C., De Moerloose, B., De Potter, C.,. Laureys, G. Benoit, Y. and Leroy. J. (1994) "Expression of the multidrug transporter. P-glycoprotein. in childhood leukemia: a prospective clinical study". International Journal of Pediatric Hematology/Oncology 1.311-314.
  • Beck, W.T., Grogan, T.M., Willman, C.L., Cordon-Cardo, C., Parham, D.M., Kuttesch, J.F. Andreef, M., Bales, S.E., Berard, C.W., Boyet, J.M., Brophy, N.A., Broxterman, H.J., Chan, H.S.L., Dalton, W.S., Dietel, M., Fojo, A.T., Gascoyne, R.D., Head, D., Houghton, P.J., Srivastava, D.K., Lehnert, M., Leith, C.P., Paietla, E., Pavelic, Z.P., Rimsza, L., Roninson, I.B., Sikic, B.I., Twenty man, P.R., Wamke, R. and Weinstein, R. (1996) "Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations", Cancer Research 56, 3010-3020.
  • Chevillard, S., Vielh, Ph. and Validire, P. (1997) "French multicentric evaluation of mdrl gene expression by RT-PCR in leukemia and solid tumours. Standardization of RT-PCR and preliminary comparisons between RT-PCR and immunohistochemistry in solid tumours". Leukemia 11. 1095- 1106.
  • Tafuri, A., Sommaggio, A., Burba, L., Albergoni, M.P., Petrucci, M.T., Mascolu, M.G., Testi, A.M. and Basso, G. (1995) "Prognostic value of rhodamine-efflux and MDR-1/P-170 expression in childhood acute leukemia". Leukemia Research 19. 927-931.
  • Beck. J., Handgretinger, R. and Kjingebiel, T. (1996) "Expression of PKC isoenzyme and MDR-associated geues in primary and relapsed state AML", Leukemia 10. 426-433.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.