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Leukemia & Lymphoma Volume 43, 2002 - Issue 2
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Research Article

Expression of P53 and Bcl-2 Proteins in T-cell Lymphoblastic Lymphoma: Prognostic Implications

K.N. Naresh Department of Pathology, Tata Memorial Hospital, Dr E. Borges Marg, Parel, Mumbai, India
,
S.D. Banavali Department of Medical Oncology, Tata Memorial Hospital, Dr E. Borges Marg, Parel, Mumbai, India
,
K.G. Bhatia Lymphoma Biology Section, National Cancer Institute, Bethesda, MD, USA
,
I. Magrath Lymphoma Biology Section, National Cancer Institute, Bethesda, MD, USA
,
C.S. Soman Department of Pathology, Tata Memorial Hospital, Dr E. Borges Marg, Parel, Mumbai, India
&
S.H. Advani Department of Medical Oncology, Tata Memorial Hospital, Dr E. Borges Marg, Parel, Mumbai, India
Pages 333-337 | Published online: 01 Jul 2009

  • Advani, S., Pai, S., Adde, M., et al. (1997) "Preliminary report of an intensified, short duration chemotherapy protocol for the treatment of pediatric non-Hodgkin's lymphoma in India". Ann. Oncol. 8, 893-897.
  • Kaiser, C., Uebelacker, I. and Havemann, K. (1999) "Non-Hodgkin's lymphoma protocols in the treatment of patients with Burkitt's lymphoma and lymphoblastic: lymphoma: a report on 58 patients", Leak. Lymph. 36, 101-108.
  • Guiterrez, M.I., Bhatia, K., Diez, B., et al. (1994) "Prognostic significance of p53 mutations in small non cleaved cell lymphomas", Int. J. Oncol. 4, 567-571.
  • Piris, M.A., Pezella, F. Martinez-Montero, J.C., et al (1994) "p53 and bel 2 expression in high grade B cell lymphomas: correlation with survival time", Br. J Cancer 69, 337-341
  • Miyashita, T. and Reed, J.C. (1993) "Bel-2 oncoprotein blocks chemotherapy-induced apoptosis in a hurman leukemia cell line", Blood 81, 151-157.
  • Hermine, O., Haioun, C., Lepage, E., et al. (1996) "Prognostic significance of bel-2 protein expression in aggressive non-Hodgkin's lymphoma", Blood 87, 265-272
  • Morel, P., Lepage, E., Brice. P., et al. (1992) "Prognosis and treatment of lymphoblastic lymphoma in adults: a report on 80 patients", J. Clin. Oncol. 10, 1078-1085.
  • Zinzani, P.L., Bendandi, M., Visani, G., et al. (1996) "Adult lymphoblastic lymphoma: clinical features and prognostic factors in 53 patients". Leuk, Lymph. 23, 577-582.
  • Villuendas, R., Piris, M.A., Algara, P., et al. (1993) "The expression of p53 protein in non-Hodgkin's lymphomas is not always dependent on p53 gene mutations". Blood 82, 3151-3156.
  • Matsushima, A.Y., Cesarman, E., Chadburn, A. and Knowles, D.M. (1994) "Post thymic T cell lymphomas frequently overexpress p53 protein but infrequently exhibit p53 gene mutations", Am. J. Pathol. 144, 573-584.
  • Paydas, S. (1995) "p53 Protein expression in leukemias", Acta Oncol. 34, 23-26.
  • Hecker, S., Sauerbrey, A. and Volm, M. (1994) "p53 expression and poor prognosis in childhood acute lymphoblastic leukemia", Anticancer Res. 14, 2759-2761.
  • Hamdy, N., Bhatia, K., Shaker, H., et al. (1995) "Molecular epidemiology of acute lymphoblastic leukemia in Egypt", Leukemia 9, 194-202.
  • Wada, M., Bartram, C.R., Nakamura, H., et al. (1993) "Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood", Blood 82, 3163-3169.
  • Nagai, J., Kigasawa, H., Koga, N., Katoh, A., Nishihira, H. and Nagao, T. (1998) "Clinical significance of detecting p53 protein in Burkitt lymphoma and B-cell acute lymphoblastic leukemia using immunocytochemistry", Leuk. Lymph. 28, 591-597.
  • Tsai, T., Davalath, S., Rankin, C., et al. (1996) "Tumor suppressor gene alternation in adult acute lymphoblastic leukemia (ALL) Analysis of retinoblastoma (Rb) and p53 gene expression in lymphoblasts of patients with de nova, relapsed, or refractory ALL treated in Southwest Oncology Group studies", Leukemia 10, 1901-1910.
  • Harrison, D.J. (1995) "Molecular mechanisms of drug resistance in tumours", J. Pathol. 175, 7-12.
  • Hinds, P.W., Finlay, C.A. and Levine, A.J. (1989) "Mutation is required to activate the p53 gene for cooperation with ras oncogene and transformation", J. Virol, 63, 739-746.
  • Lane, D. and Benchimol, S. (1990) "p53; oncogene or anti-oncogene?", Genes Rev. 4, 1-3.
  • Harris, A. (1990) "Mutant p53-the commonest genetic abnormality in human cancer?", J. Pathol. 162, 5-6.
  • Bartek, J., Iggo, R., Gannon, J., et al. (1990) "Genetic and immunohistochemical analysis in human breast cancer cell lines", Oncogene 5, 893-899.
  • Coustan-Smith, E., Kitanaka, A., Pui, C.H., et al. (1996) "Clinical relevance of BCL-2 overexpression in childhood acute lymphoblastic leukemia", Blood 87, 1140-1146.
  • Naumovski, L., Martinovsky, G., Wong, C., et al. (1998) "BCL-2 expression does not correlate with patient outcome in pediatric acute myelogenous leukemia", Leuk. Res. 22, 81-87.
  • Jaeger, U., Karth, G.D., Knapp, S., Friedl, J., Laczika, K. and Kusec, R. (1994) "Molecular mechanism of the t(14;18)--A model for lymphoid-specific chromosomal translocations", Leuk, Lymph. 14, 197-202.

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