Advanced search
Publication Cover
Leukemia & Lymphoma Volume 43, 2002 - Issue 3
Submit an article Journal homepage
33
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Influence of Tumor Vaccines on Graft Versus Tumor Activity and Graft Versus Host Disease in Allogeneic Bone Marrow Transplantation

Craig A. Mullen Department of Pediatrics, University of Texas M.D. Anderson Cancer Center, Box 88 1515 Holcombe Blvd., Houston, TX 77030, USA
Pages 503-510 | Published online: 01 Jul 2009

  • Sullivan, K.M., Storb, R., Buckner, C.D., Fefer, A., Fisher, L., Weiden, P.L., Witherspoon, R.P., Appelbaum, F.R., Banaji, M., Hansen, J., Martin, P., Sanders, J.E., Singer, J. and Thomas, E.D. (1989) "Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms", New Engl. J Med. 320, 828-834.
  • Sullivan, K.M., Weiden, P.L., Storb, R., Witherspoon, R.P., Fefer, A., Fisher, L., Buckner, C.D., Anasetti, C., Appelbaum, F.R., Badger, C., et al., (1989) "Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia", Blood 73, 1720-1728.
  • Horowitz, M.M., Gale, R.P., Sondel, P.M., Goldman, J.M., Kersey, J., KoIb, H.J., Rimm, A.A., Ringden, O., Rozman, C., Speck, B., et al., (1990) "Graft-versus-leukemia reactions after bone marrow transplantation", Blood 75, 555-562.
  • Rizzo, J.D. (1998) "Current trends in BMT", ABMTR Newslett. 5, 4-10.
  • Advisory Committee of the International Bone Marrow Transplant Registry (1989) "Report from the international bone marrow transplant registry", Bone Marrow Transplant. 4, 221-228.
  • Goulmy, E. (1996) "Human minor histocompatibility antigens", Curr. Opin. Immunol. 8, 75-81.
  • de Bueger, M., Bakker, A., Van Rood, J.J., Van der Woude, F. and Goulmy, E. (1992) "Tissue distribution of human minor histocompatibility antigens. Ubiquitous versus restricted tissue distribution indicates heterogeneity among human cytotoxic T-lymphocyte-defined non-MHC antigens", J Immnnol. 149, 1788-1794.
  • van Lochem, E., de Gast, B. and Goulmy, E., (1992) "In vitro separation of host specific graft-versus-host and graft-versus-leukemia cytotoxic T-cell activities", Bone Marrow Transplant. 10, 181-183.
  • Hoffmann, T., Theobald, M., Bunjes, D., Weiss, M., Heimpel, H. and Heit, W. (1993) "Frequency of bone marrow T-cells responding to HLA-identical non-leukemic and leukemic stimulator cells", Bone Marrow Transplant. 12, 1-8.
  • Datta, A.R., Barrett, A.J., Jiang, Y.Z., Guimaraes, A., Mavroudis, D.A., van Rhee, F., Gordon, A.A. and Madrigal, A. (1994) "Distinct T-cell populations distinguish chronic myeloid leukaemia cells from lymphocytes in the same individual: a model for separating GVHD from GVL reaction", Bone Marrow Transplant. 14, 517-524.
  • Green, MC. and Witham, B.A. (1991) Handbook on genetically standardized Jax mice (Jackson Laboratory, Bar Harbor, Maine).
  • Korngold, R. and Sprent, J. (1987) "Variable capacity of L3T4+ T-cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice", J. Exp. Med. 165, 1552-1564.
  • Simpson, E. and Roopenian, D. (1997) "Minor histocompatibility antigens", Curr. Opin. Immunol. 9, 655-661.
  • Korngold, R. and Sprent, J.(1978) "Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice: prevention by removing mature T-cells from marrow", J. Exp. Med. 148, 1687-1698.
  • Sprent, J. and Korngold, R. (1994) In: Forman, S.J., Blume, K.G. and Thomas, E.D., eds, Bone Marrow Transplantation (Blackwell, Oxford), pp 220-230.
  • Eden, P.A., Christianson, G.J., Fontaine, P. Wettstein, P.J., Perreault, C. and Roopenian, D.C. (1999) "Biochemical and immunogenetic analysis of an immunodominant peptide (B6doml) encoded by the classical H7 minor histocompatibility locus", J. Immunol. 162, 4502-4510.
  • Perreault, C., Jutras, J., Roy. D.C., Filep, J.G. and Brochu, S. (1996) "Identification of an immunodominant mouse minor histocompatibility antigen (MiHA). T-cell response to a single dominant MiHA causes graft-versus-host disease", J. Clin. Invest. 98, 622-628.
  • Zuberi, A.R., Christianson, G.J., Mendoza, L.M., Shastri, N. and Roopenian, D.C. (1998) "Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex", Immunity 9, 687-698.
  • Mendoza, L.M., Paz, P., Zuberi, A., Christianson, G., Roopenian, D. and Shastri, N. (1997) "Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex", Immunity 7, 461-472.
  • Anderson, L.J., Petropoulus, D., Everse, L.A and Mullen, C.A. (1999) "Enhancement of graft-versus-tumor activity and graft-versus-host disease by pretransplant immunization of allogeneic bone marrow donors with a recipient-derived tumor cell vaccine", Cancer Res. 59, 1525-1530.
  • Pion, S., Christianson, G.J., Fontaine, P., Roopenian, D.C. and Perreault, C. (1999) "Shaping the repertoire of cytotoxic T-lymphocyte responses: explanation for the immunodominance effect whereby cytotoxic T-lymphocytes specific for immunodominant antigens prevent recognition of nondominant antigens", Blood 93, 952-962.
  • Anderson, L.D., Savary, C.A. and Mullen, C.A. (2000) "Immunization of allogeneic bone marrow transplant recipients with tumor cell vaccines enhances graft-versus-tumor activity without exacerbating graft-versus-host disease", Blood 95, 2426-2433.
  • Bastin, J., Rothbard, J., Davey, J., Jones, I. and Townsend, A. (1987) "Use of synthetic peptides of influenza nucleoprotein to define epitopes recognized by class I-restricted cytotoxic T"-lymphocytes", J. Exp. Med. 165, 1508-1523.
  • Townsend, A.R.M., Gotch, F.M. and Davey, J. (1985) "Cytotoxic T-cells recognize fragments of the influenza nucleoprotein", Cell 42, 457-467.
  • Mullen, C.A., Anderson. L., Woods, K., Nishino, M. and Petropoulos, D. (1993) "Ganciclovir chemoablation of herpes thymidine: kinase suicide gene-modified tumors produces tumors necrosis and induces systemic immune responses", Hum. Gene Ther. 9, 2019-2030.
  • Ochsenbein, A.F., Klenerman, P., Karrer, U., Ludewig, B., Pericin, M., Hengartner and Zinkernagel, R.M. (1999) "Immune surveillance against a solid tumor fails because of immunological ignorance", Proc Natl Acad. Sci. USA 96, 2233-2238.
  • Anderson, L.D., Mori, S., Mann, S., Savary, C.A. and Mullen, C.A. (2000) "Pretransplant tumor antigen-specific immunization of allogeneic bone marrow transplant donors enhances graft-versus-tumor activity without exacerbation of graft-versus-host disease", Cancer Res. 60, 5797-5802.
  • Truitt, RL., Johnson, B.D., Hanke, C., Talib, S. and Hearst, J.E. (1999) "Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation", J. Immunol. 163, 5145-5156.
  • Bordignon, C., Bonini, C., Verzeletti, S., Nobili, N., Maggioni, D., Traversari, C., Giavazzi, R., Servida, P., Zappone, E., Benazzi, E., et al., (1995) "Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation", Hum. Gene Ther. 6, 813-819.
  • Teshima, T., Mach, N., Hill, G.R., Pan, L., Gillessen, S., Dranoff, G. and Ferrara, J.L. (2001) "Tumor cell vaccine elicits potent or immunity after allogeneic T-cell-depleted bone marrow transplantation", Cancer Res. 61, 162-171.
  • Bendandi, M., Gocke, C.D., Kobrin, C.B., Benko, F.A., Sternas, L.A., Pennington, R., Watson, T.M, Reynolds, C.W., Gause, B.L., Duffey, P.L., Jaffe, E.S., Creckmore, S.P., Longo, D.L. and Kwak, L.W. (1999) "Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma", Nat. Med. 5, 1171-1177.
  • Biragyn, A. and Kwak, L.W. (1999) "B-cell malignancies as a model for cancer vaccines: from prototype protein to next generation genetic chemokine fusions", Immunol. Rev. 170, 115-126.
  • Clave, E., Molldrem, J., Hensel, N., Raptis, A. and Barrett, A.J. (1999) "Donor-recipient polymorphism of the proteinase 3 gene: a potential target for T-cell alloresponses to myeloid leukemia", J. Immunotherapy 22, 1-6.
  • Molldrem, J.J., Clave, E., Jiang, Y.Z., Mavroudis, D., Raptis, A., Hensel, N., Agarwala, V. and Barrett, A.J. (1997) "Cytotoxic T-lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units", Blood 90, 2529-2534.
  • Everse, L.A., Anderson, L.D., Rooijen, N. and Mullen, C.A. (2001) "Bone marrow transplant conditioning intensified with liposomal elodronate to eliminate residual host antigen presenting cells fails to ameliorate GVHD and increases peri-BMT mortality", Transplantation 71, 611-618.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.