51
Views
18
CrossRef citations to date
0
Altmetric
Research Article

Stem Cell Factor-induced Bone Marrow Mast Cell Hyperplasia Mimicking Systemic Mastocytosis (SM): Histopathologic and Morphologic Evaluation with Special Reference to Recently Established SM-criteria

, , , , , , , , & show all
Pages 575-582 | Published online: 01 Jul 2009

  • Lennert, K. and Parwaresch, M.R. (1979) "Mast cells and mast cell neoplasia: a review", Histopatholgy 3, 349-356.
  • Parwaresch, M.R., Horny, H.-P. and Lennert, K. (1985) "Tissue mast cells in health and disease", Pathology Research and Practice 179, 439-461.
  • Mctcalfe, D.D. (1991) "Classification and diagnosis of mastocytosis: current status", Journal of Investigative Dermatology 96, 2S-4S.
  • Parwaresch, M.R., Horny, H.-P. and Bödewadt-Radzun, S. (1992) "Mast cell disease", In: Knowles, D.M., ed. Neoplastic Hematopathology (William & Wilkins, New York), pp 1485-1515.
  • Valent, P. (1996) "Biology, classification and treatment of human mastocytosis", Wiener Klinische Wochenschrift 108, 385-397.
  • Caplan, R.M. (1963) "The natural course of urticaria pigmentosa. Analysis and follow up of 112 cases", Archives of Dermatology 87, 146-157.
  • Horan, R.F and Austen, K.F. (1991) "Systemic mastocytosis: retrospective review of a decade's clinical experience at the Brigham and Women's hospital", Journal of Investigative Dermatology 96, 5-13.
  • Travis, W.D., Li, C.Y., Bergstralh, E.J., Yam, L.T. and Swee, R.G. (1988) "Systemic mast cell disease. Analysis of 58 cases and literature review", Medicine 67, 345-368.
  • Nagata, H., Worobec, A.S., Oh, C.K., Chowdhury, B.A., Tannenbaum, S., Suzuki, Y. and Metcalfe, D.D. (1995) "Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder", Proceedings of the National Academy of Sciences of the USA 92, 10560-10564.
  • Longley, B.J., Tyrrell, L., Lu, S.Z., Ma, Y.S., Langley, K., Ding, T.G., Duffy, T., Jacobs, P., Tang, L.H. and Modlin, I. (1996) "Somatic c-kit activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm", Nature Genetics 12, 312-314.
  • Worobec, A.S., Semere, T., Nagata, H. and Metcalfe, D.D. (1998) "Clinical correlates of the presence of the Asp816 Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis", Cancer 83, 2120-2129.
  • Buttner, C., Henz, B.M., Welker, P., Sepp, N.T. and Grabbe, J. (1998) "Identification of activating c-kit mutations in adult-, but not childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behaviour", Journal of Investigative Dermatology 111, 1227-1231.
  • Longley, B.J., Metcalfe, D.D., Tharp, M., Wang, X., Tyrrell, L., Lu, S.-Z., Heitjan, D. and Ma, Y. (1999) "Activating and dominant inactivating c-kit catalytic domain mutations in distinct forms of human mastocytosis", Proceedings of the National Academy of Sciences of the USA 96, 1609-1614.
  • Escribano, L., Orfao, A., Diaz-Agustin, B., Villarrubia, J., Cerveró, C., Lopez, A., Marcos, M.A., Bellas, C., Fernández-Canadas, S., Cuevas, M., Sánchez, A., Velasco, J.L., Navarro, J.L. and Miguel, J.F. (1998) "Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications", Blood 91, 2731-2736.
  • Valent, P., Horny, H.-P., Escribano, L., Longley, J.B., Li, C.Y., Schwartz, L.B., Marone, G., Nunez, R., Akin, C., Sotlar, K., Sper, W.R., Wolff, K., Brunning, R.D., Parwaresch, R.M., Austen, K.F., Lennert, K., Metcalfe, D.D., Vardiman, J.W. and Bennett, J.M. (2001) "Diagnostic criteria and classification of mastocytosis: a consensus proposal", Leukemia Research 25, 603-625.
  • Malone, D.G., Wilder, R.L., Saavedra-Delgado, A.M. and Melcalfe, D.D. (1987) "Mast cell numbers in rheumatoid synovial tissues. Correlations with quantitative measures of lymphocytic infiltration and modulation by anti-inflammatory therapy", Arthritis Rheumatism 30, 130-137.
  • Toth-Jakstics, R., Jimi, S., Takebayashi, S. and Kawamoto, N. (2000) "Cutaneous malignant melanoma: correlation between neovascularization and peritumor accumulation of mast cells overexpressing vascular endothelial growth factor", Human Pathology 31, 955-960.
  • Takanami, L, Takeuchi, K. and Naruke, M. (2000) "Mast cell density is associated with angiogenesis and poor prognosis in pulmonary adenocarcinoma", Cancer 88, 2686-2692.
  • Yoo, D. and Lessin, L.S. (1982) "Bone marrow mast cell content in preleukemic syndrome", American Journal of Medicine 73, 539-542.
  • Prokocimer, M. and Polliack, A. (1981) "Increased bone marrow mast cells in preleukemic syndromes, acute leukemia, and lymphoproliferative disorders", American Journal of Clinical Pathology 75, 34-38.
  • Födinger, M., Fritsch, G., Winkler, K., Emminger, W., Mitterbauer, G., Gadner, H., Valent, P. and Mannhalter, C. (1994) "Origin of human mast cells: development from transplanted hematopoietic stem cells after allogeneic bone marrow transplantation", Blood 84, 2954-2959.
  • Naeim, F., Smith, G.S. and Gale, R.P. (1978) "Morphologic aspects of bone marrow transplantation in patients with aplostic anemia", Human Pathology 9, 295-308.
  • de Planque, M.M., van Krieken, J.H., Kluin-Nelemans, H.C., Colla, L.P., van der Burgh, F. Brand, A. and Kluin, P.M. (1989) "Bone marrow histopathology of patients with severe aplastic anemia before treatment and at follow up", British Journal of Haematology 72, 439-444.
  • Hsu, S.M., Raine, L. and Fanger, H. (1981) "Use of avidin-biotinperoxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures", Journal of Histochemistry and Cytochemistry 29, 577-580.
  • Jordan, J.-H., Walchshofer, S., Jurecka, W., Mosberger, I., Sperr, W.R., Wolff, K., Chott, A., Bühring, H.-J. Lechner, K., Horny, H.-P. and Valent, P. (2001) "Phenotypic properties of mast cells in patients with systemic mastocytosis: evidence for abnormal expression of CD2, CD117/c-kit, and bcl-X1 ", Human Pathology 32, 545-552.
  • Shi, S.R., Key, M.E. and Kalra, K.L. (1991) "Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochem cal staining based on microwave oven heating of tissue sections", Journal of Histochemistry and Cytochemistry 39, 741-748.
  • Cattoretti, G., Pileri, S., Parravicini, C., Becker, M.H., Poggi, S., Bifulco, C., Key, G., Dàrnato, L., Sabattini, E. and Feudale, E. (1993) "Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections", Journal of Pathology 171, 83-98.
  • Butterfield, J.H., Weiler, D., Dewald, G. and Gleich, G.J. (1988) "Establishment of an immature mast cell line from a patient with mast cell leukemia", Leukemia Research 12, 345-355.
  • Sambrook, J., Frilsch, E.F. and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual (Cold Spring Harbor Laboratory Press, New York).
  • Yarden, Y., Kuang, W.J., Yang-Feng, T., Coussens, L., Munemitsu, S., Dull, T.J., Chen, E., Schlessinger, J., Francke, U. and Ullrich, A. (1987) "Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand", EMBO Journal 6, 3341-3351.
  • Schwartz, L.B., Sakai, K., Bradford, T.R., Ren, S., Zweiman, B., Worobec, A.S. and Metcalfe, D.D. (1995) "The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis", Journal of Clinical investigation 96, 2702-2710.
  • Schwartz, L.B., Metcalfe, D.D., Miller, J.S., Earl, H. and Sullivan, T. (1987) "Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis", New England Journal of Medicine 316, 1622-1626.
  • Horny, H.-P., Parwaresch, M.R. and Lennert, K. (1985) "Bone marrow findings in systemic mastocytosis", Human Pathology 16, 808-814.
  • Horny, H.-P. and Valent, P. (2001) "Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings", Leukemia Research 25, 543-551.
  • Sperr, W.R., Escribano, L., Jordan, J.-H., Schemthaner, G.-H., Kundi, M., Horny, H.-P. and Valent, P. (2001) "Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis", Leukemia Research 25, 529-536.
  • Furitsu, T., Tsujimura, T., Tono, T., Ikeda, H., Kitayama, H., Koshimizu, U., Sugahara, H., Butterfield, J.H., Ashman, L.K., Kanayama, Y., Matsuzawa, Y., Kitamura, Y. and Kanakura, Y. (1993) "Identification of mutation in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product", Journal of Clinical Investigation 92, 1736-1744.
  • Valent, P., Escribano, L., Parwaresch, R., Schemmel, V., Schwartz, L.B., Sotlar, K., Sperr W.R. and Horny, H.-P. (1999) "Recent advances in mastocytosis research", International Archives of Allergy and Immunology 120, 1-7.
  • Eseribano, L., Díaz-Agustín, B., Bellas, C., Navalón, R., Nunez, R., Sperr, W.R., Schemthaner, G.H., Valent, P. and Orfao, A. (2001) "Utility of flow cytometric analysis of mast cells in the diagnosis and classification of adult mastocytosis", Leukemia Research 25, 563-570.
  • Longley, B.J., Reguera, M.J. and Ma, Y. (2001) "Classes of c-kit activating mutations: proposed mechanisms of action and implications of disease classification and therapy", Leukemia Research 25, 571-576.
  • Fritsche-Polanz, R., Jordan, J.H., Feix, A., Sperr, W.R., Sunder-Plassmann, G., Valent, P. and Födinger, M. (2001) "Mutation analysis of C-KIT in patients with myelodysplastic syndromes without mastocytosis and cases with mastocytosis", British Journal of Haematology 113, 357-364.
  • Schwartz, L.B. (2001) "Clinical utility of tryptase levels in systemic mastocytosis and associated hematologic disorders", Leukemia Research 25, 553-562.
  • Sperr, W.R., Jordan, J.H., Baghestanian, M., Kiener, H., Samorapoompichit, P., Semper, H., Hauswirth, A., Chott, A., Natter, S., Kraft, D., Valenta, R., Schwartz, L.B., Geissler, K., Lechner, K. and Valent, P. (2001) "Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia", Blood, 98, 2200-2209.
  • Valent, P., Spanblöchl, E., Sperr, W.R., Sillaber, C., Zsebo, K.M., Agis, H., Strobl, H., Geissler, K., Bettelheim, P. and Lechner, K. (1992) "Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor (SCF)/kit ligand in long term culture", Blood 80, 2237-2245.
  • Kirshenbaum, A.S., Goff, J.P., Kessler, S.W., Mican, J.M., Zsebo, K.M. and Metcalfe, D.D. (1992) "Effects of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ pluripotent progenitor cells", Journal of Immunology 148, 772-777.
  • Valent, P. (1994) "The riddle of the mast cell: c-kit ligand as missing link ?", Immunology Today 15, 111-114.
  • Costa, J.J., Demetri, J.D., Harrist, T.J., Dvorak, A.M., Hayes, D.F., Merica, E.A., Menchaca, D.M., Gringeri, A.J., Schwartz, L.B. and Galli, S.J. (1996) "Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo", Journal of Experimental Medicine 183, 2681-2686.
  • Galli, SJ., Iemura, A., Garlick, D.S., Gamba-Vitalo, C., Zsebo, K.M. and Andrews, R.G. (1993) "Reversible expansion of primate mast cell populations in vivo by stem cell factor", Journal of Clinical Investigation 91, 148-152.
  • Bischoff, S.C. and Dahinden, C.A. (1992) "c-kit ligand: a unique potentiator of mediator release by human lung mast cells", Journal of Experimental Medicine 175, 237-244.
  • Sperr, W.R., Czerwenka, K., Mundigler, G., Müller, M.R., Semper, H., Klappacher, G., Glogar, D., Lechner, K. and Valent, P. (1993) "Specific activation of human mast cells by the ligand for c-kit: comparison between lung-, uterus- and heart mast cells", International Archives of Allergy and Applied Immunology 102, 170-175.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.