99
Views
18
CrossRef citations to date
0
Altmetric
Research Article

The Role of Donor Age in Naive T-cell Recovery Following Allogeneic Hematopoietic Stem Cell Transplantation: The Younger the Better

, , &
Pages 735-739 | Published online: 01 Jul 2009

  • Kernan, N.A., Bartseh, G., Ash, R.C., Beatty, P.G., Champlin, R., Filipovich, A., Gajewski, J. Hansen, J.A., Henslee-Downey. J. and McCullough. J. (1993) "Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program", N. Engt. J Med. 328, 593-602.
  • Balduzzi, A., Gooley, T., Anasetti, C. Sanders, J.E., Martin, P.J., Petersdorf, E.W. Appelbaum, F.R., Buckner, C.D., Matthews, D. and Storb, R. (1995) "Unrelated donor marrow transplantation in children", Blood 86, 3247-3256.
  • Gluckman, E., Rodia, V., Boyer-Chammard, A., Locatelli, F., Arcese, W., Pasquini, R., Ortega, J., Souillet, G., Ferreira, E., Laporte, J.P., Fernandez, M. and Chastang, C. (1997) "Outcome of cord-blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Trartsplantation Group", N. Engl. J. Med. 337, 373-381.
  • Hausen, J.A., Gooley, T.A., Martin, P.J., Appelbaum, F., Chauncey, T.R., Clift, R.A., Petersdorf, E.W, Radich, J., Sanders, J.H. Storb, R.F. Sullivan, K.M. and Anasetti, C. (1998) "Bone marrow transplanis from unrelated donors for patients with chronic myeloid leukemia", N. Engl. J. Med. 338, 962-968.
  • Kuntzberg, J., Laughlin, M., Graham, M.L., Smith, C., Olson, J.F., Halperin, E.C., Ciocci, G., Carrier, C., Stevens, C.E and Rubinstein, P. (1996) "Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients", N. Engl. J. Med. 335, 157-166.
  • Rubinstein, P., Carrier, C., Scaradavou, A., Kurtzberg, J., Adamson, J., Migliaccio, A.R., Berkowitz, R.L., Cabbad, M., Dobrila, N.L., Taylor, P.E., Rosenfeild, R.E. and Stevens, C.E. (1998) "Outcomes among 562 recipients of placemal-blood transplants from unrelated donors", N. Engt. J. Med. 339, 1565- 1577
  • Speiser, D.E., Tierey, J.M., Rufer, N., Grundschober, C., Gratwohl, A., Chapuis, B., HeIg, C., Loliger, C.C., Siren, M. K., Roosnek, E. and Jeannet, M. (1996) "High resolution HLA matching associated with decreased mortality after unrelated hone marrow transplantation", Blood 87, 4455-4462.
  • Davies, S.M., Shu, X.O., Blazar, B.R., Filipovich, A.H., Kersey, J.H., Krivit, W. McCuIlough, J., Miller, W.J., Rarnsay, N.K. and Segall, M. (1995) 'Unrelated donor bone marrow transplantation: influence of HLA A and B incompatibility on outcome". Blood 86, 1636-1642.
  • Petersdorf, L.W., Longton, G.M., Anasetti, C., Martin, P.J., Mickelson, E.M., Smith, A.G. and Hansen, J.A. (1995) "The significance of HLA-DRBI matching on clinical outcome after HLA A. B. DR identical unrelated donor marrow transplantation", Blood 86, 1606-1613.
  • Small, T.N., Papadopoulos, E.B., Boulad, F., Black, P. CastroMalaspina, H., Childs, B.H., Collins, N., Gillio, A., George, D., Jakubowski, A., Heller, G., Fazzari, M., Kernan, N., MacKinnon, S., Szuboles, P. Young, J.W. and O'Reilly, R.J. (1999) "Comparison of immune reconstitution after unrelated and related T-cell-depieted bone marrow transplantation: effect of patient age and donor leukocyte infusions", Blood 93, 467-480
  • Kook, H., Goldman, F., Padley, D., Culler, R., Rumethart, S. Holida. M., Lee, N., Peters, C., Comito, M., Huling, D. and Trigg, M. (1996) "Reconstruction of the immune system after unrelated or partially matched T-cell-depIeled bone marrow transplantation m children: immunophenotypic analysis and factors affecting the speed of recovery", Blood 88, 1089-1097.
  • Bonno, M., Azuma, E., Nakano, T., Higashikawa, M., Kawasaki. H., Nishihara, H., Obata, M., Umemoto, M., Sakatoku, H., Komada, Y. Ito, M., Nagai, M. and Sakurat, M. (1997) "Successful hematopoielic recunstitution by transplantation of umbilical cord blood cells in a transfusion-dependent child with DiamondBlackfan anemia", Bone Marrow Transplant. 19, 83-85.
  • Azuma, E., Hirayama, M., Bonno, M., Iwamoto. S., Kumamoto, T., Kobayushi, M., Komada, Y., Taniguchi, K., Nakano, T. and Kamiya, H. (2001) "Successful immunization following cord blood transplantation in a child with Diamond-Blackfan anemia", Pediatr. Hemtol. Oncol. 18, 193-197.
  • Davenport, C., Kumar, V. and Bennett, M, (1993) "Use of newborn liver cells as a murine model for cord blood cell transplantation", J. Immunol. 151, 1597-1605.
  • Hirayama, M., Genyea, C., Brownell, A. and Kaplan, J. (1998) "IL 2-activated murine newborn liver NK cells enhance engraftment of hematopoielic stem cells in MHC-mismaiched recipients", Bone Marrow Transplant. 21, 1245-1252.
  • Scaradavou, A., Isola, L., Rubinstein, P., Galperin, Y., Najfeld, V. Berlin, D., Gordon, J. and Weinberg, R.S. (1997) "A murine model for human cord blood transplantai ion: near-term fetal and neonatal peripheral blood cells can achieve long-term bone marrow engraftmenl in sublethally irradiated adult recipients", Blood 89, 1089-1115.
  • Hirayarna, M., Azuma, E., Jiang, Q., Kobayashi, M., Iwarnoin, S. Kumamoto. T., Kisenge. R., Yamamoto, H. and Komada, Y. (2000) "The reconstitution of CD45RBhiCD4+ naive T-cell.s is inversely correlated with donor age in murine allogenere haematopoietic stem cell transplantation", Br. J. Haenmatol. 111, 700-707.
  • Offner, F., Kerre, T., De Smedt, M and Plum. J. (1999) "Bone marrow CD34 cells generate fewer T-cellb in vitro with increasing age and following chemotherapy", Br. J. Haematol. 104, 801-808.
  • Eren, R., Zharhary. D., Abel, L. and Globerson, A. (1988) "Agerelated changes in the capacity of bone marrow cells to differentiate in thymic organ cultures", Cell I mmimal. 112, 449-455.
  • Lee, W.T., Yin, X.M. and Vitetta, E.S. (1990) "Functional and ontogenetic analysis of murine CD45Rhi and CD45RIo CD4+ T-cells", J Immunol 144, 3288-3295.
  • Nagelkerken, L., Henogh-Huijbregts, A., Dobber, R. and Drager, A. (1991) "Age related changes in lymphokine production related to a decreased number of CD54RBhi CD4+ T-cells", Eur J Immunol. 21, 273-281.
  • Rufer, N., HeIg, C., Chapuis, B. and Roosnek, E. (2001) "Human memory T-cells: lessons from stem cell transplantation", Trends Immunol. 22, 136-141.
  • Paulin, T., Ringden, O. and Nilsson, B. (1987) "Immunological recovery alter bone marrow transplantation: role of age. graft versus-host disease, prednisolone treatment and infections", Bone Marrow Trunsplant. 1, 317-328.
  • Kawamoto, H., Ohmura, K., Hattori, N. and Katsunt, Y. (1997) "Memopoietic progenitors in the murine fetal liver capable of rapidly generating T-cells", J. Immunol. 158, 3118-3124.
  • Mackall, C.L., Granger, L., Sheard, M.A., Cepeda, R. and Gress, RE. (1993) "T-cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thyinic-independem progeny", Blood 82, 2585-2594.
  • Mackall, C.L., Fleisher, T.A., Brown, M.R., Andrich, M.P., Chen, C.C., Feuerstein. I.M., Horowitz, M.E., Magrath, I.T., Shad, A.T. and Steinberg, S.M. (1995) "Age. thymopoiesis, and CD4+ T-lymphocyle regeneration after intensive chemotherapy", N. Engl. J. Med. 332, 143-149.
  • Weinberg, K., Blazar, B.R., Wagner, J.E., Agura, H., Hill, B.J., Smogorzewska, M., Koup, R.A., Betts, M.R., Collins, R.H. and Douck, D.C. (2001) "Factors, affecting thymic function after allogeneic hematonoietic stem cell transplantation", Blood 97, 1458-1466.
  • Heitger, A., Neu, N., Kern, H., Panzer-Grumayer, E.R., Greinix, H., Nachbaur, D., Niederwieser, D. and Fink, F.M. (1997) "Essential role of the thymus to reconstitute naive (CD45RA+) T-helper cells after human allogeneic bone marrow transplantation", Bloosd 90, 850-857.
  • Wolf, H.M., Eibl, M.M., Georgi, E., Samstag. A., Spatz, M., Uranus, S. and Passl, R. (1999) "Long-term decrease of CD4+CD45RA+ T cells and impaired primary immune response after post-traumatic spleneclomy (In Process Citation)", Br. J. Haematol. 107, 55-68.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.