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Research Article

Humoral Immunodeficiency in Chronic Lymphocytic Leukemia: Role of CD95/CD95L in Tumoral Damage and Escape

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Pages 881-884 | Published online: 01 Jul 2009

  • Sampalo, A., Navas, G., Medina, F., Segundo, C., Camara, C. and Brieva, J.A. (2000) "Chronic lymphocytic leukemia B cells inhibit spontaneous Ig production by autologous bone marrow cells: role of CD95-CD95L interaction", Blood 96. 3168-3174.
  • Dighiero, G., Travade, P., Chevret, S., Fenaux, P., Chastang, C. and Binet. J.L. (1991) "B-cell chronic lymphocytic leukemia: present status and future directions", Blood 78, 1901-1910.
  • O'Brien, S., del Giglio, A. and Keating, M. (1995) "Advances in the biology and treatment of B cell chronic lymphatic leukaemia'. Blood 85, 307-318.
  • Hardy, R.R. and Hayakawa, K. (1994) "CD5 B cells, a letal B cell lineage", Adv. Immunol. 55, 297-339.
  • Youinou, P., Jamin, C. and Lydyard, P.M. (1991) "CDS expression in human B cell populations", Immunol. Today 1920, 312-316.
  • Rozman, C. and Monserrat, E. (1995) "Chronic lymphocytic leukaemia", New Eng. J. Med. 333, 1052-1057.
  • Chapel, H. (1987) "Hypogammaglobulinemia and chronic lymphocytic leukaemia", In: Gale, R.P. and Kai, KR., eds. Chronic Lymphocytic Leukemia: Recent Progress and future Directions Proceedings of UCLA Symposia on Molecular and Cell Biology (Liss, New York), pp 383-384.
  • Clone, I., and Uhr, J.W. (1964) "Immunological deficiency disorders associated with chronic lymphocytic leukaemia and multiple myeloma", J. Clin. Invest. 43, 2241-2247.
  • Chapel, H. and Buch, C. (1987) "Mechanism of infections in chronic lymphatic leukaemia", Semin. Hematol. 24, 291-296.
  • Fiddes, P., Penny, R. and Wells, J.V. (1972) "Clinical correlations with immunoglobulin levels in chronic lymphatic leukaemia", Aust NZ J. Med 2, 346-350.
  • Kay, N.K. (1981) "Abnormal T-cell subpopulation function in CLL, Excessive suppressor and deficient helper (T) activity with respect to B-cell proliferation", Blood 57, 418-420.
  • Chiorazzi, N., Fu, S.M., Moniazeri, G., Kunkel, H.G., Rai, K. and Gee, T (1979) "T cell helper defect in patients with chronic lymphocytic leukaemia", J. Immunol 122, 1087-1090.
  • Kurec, A.S. and Davey, F.R. (1987) "Impaired synthesis of immunoglobulin in patients with chronic lymphocytic leukemia", Am. J. Hematol. 25, 131-142.
  • Kay, N.E. and Perry, R.T. (1989) "Evidence that large granular lymphocytes from B-CLL patients with hypogammaglobulinemia down-regulate B-cell immunoglohulin synthesis", Blood 73, 1016-1019.
  • Cheson, B.D., Bennet, J.M., Grever, M., Kay, N., Keating, M.J., O'Brien, S. and Rai, K.R. (1996) "National Cancer Institute sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment", Blood 87, 4990-4997.
  • Shimoni, A., Marcus, H., Canaan, A., Ergas, D., David, M., Berrebi, A. and Reisner, Y. (1997) "A model for human B-chronic lymphocytic leukemia in human/mouse radiation chimera: Evidence for tumor-mediated suppression of antibody production in low stage disease", Blood 89, 2210-2218.
  • Tinhoffer, I., Marschitz, I., Koss, M., et al. (1998) "Differential sensitivity of CD4+ and CD8- T lymphocytes to the killing efficacy of Fas (Apo-1/CD95) ligand tumor cells in B chronic lymphocytic leukemia", Blood 91, 4273-4281.
  • Nagata, S. and Golstein, P. (1995) "The Fas death receptor", Sceince 267, 1449-1456.
  • Cerutti, A., Kiml, E.C., Shah, S., et al. (2001) "Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells", Nature Immunol. 2, 150-156.
  • Cantwell, M., Hua, T., Pappas, J. and Kipps, T.J (1997) "Acquired CD40-ligand deficiency in chronic lymphatic leukemia", Nature Med. 3, 984-989.
  • Slavnezer, J. (1996) "Antibody class switching", Adv. Immunol 61, 79-146.
  • Lacombe, C., Gombert, J., Dreyfus, B., Brizard, A. and Preud'Homme, J.L. (1999) "Heterogeneity of serum IgG subclass deficiencies in B chronic lymphocytic leukemia", Clin. Immunol. 90, 128-132.
  • Macmillan, R., Longmire, R.L., Yelenosky, K., Lang, J.H., Heath, V. and Craddok, C.G. (1972) "Immunoglobulin synthesis by human lymphoid tissues: normal bone marrow as a major site of IgG production" J. Immunol. 109, 1386-1394.
  • Benner R., Hijmans, W. and Haaijman, J.J. (1981) "The bone marrow: the major source of immunoglobulins, but still neglected site of antibody formation", Clin. Exp. Immunol. 46,1-8.
  • Leithauser, F., Dhein, H., Mechtersheimer, G., Koretz, K., Bruederlein, S., Henn, C., Schmidt, A., Debatin, K.M., Krammer, P.H. and Moeller, P. (1993) "Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily in normal and neoplastic cells", Lab. Invest. 69, 415-429.
  • Abbas, A.K. (1996) "Die and let live: eliminating dangerous lymphocytes", Cell 84, 655-657.
  • Medina, F., Segundo, C., Rodriguez, C. and Brieva, J.A. (1997) "Regulatory role of CD95 ligation on human B cells induced in vivo capable of spontaneous and high rate Ig secretion", Eur. J. Immunol. 27, 700-706.
  • Ashwelt, J.D. Berger, N.A., Cidlowski, J.A., Lane, D.P. Korsmeyer, S.J. and Ashwell, J.D. (1994) "Coming to terms with death: apoptosis in cancer and immune development", Immunol. Today 15, 147-151.
  • Nagata, S. and Suda, P. (1995) "Fas and fas-ligand: lpr and gld mutations", Immunol. Today. 16, 39-43.
  • Fisher, G.H., Rosenberg, F.J., Strauss, S.E., Dale, J.K., Middelton, L. A., Linn. A.Y, Stroher, W., Lenardo, M.J. and Puck, J.M. (1995) "Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome", Cell 81, 935-946.
  • O'Connell, J. Houston, A. Bennet, M.W., O'Sullivan, G.C. and Shanahan, F. (2001) "Immune privilege or inflammation? Insights into the fas ligand enigma", Nature Med. 7, 271-274.
  • Stassy, G., Liberto, D., Todaro, M., Zeuner, A., Ricci-Vittani, L., Stoppacioro, A., Ruco, L., farina, F., Zummo, G. and De Maria, R. (2000) "Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins", Nature Immunol. 1, 461-462.
  • Viard, I., Wehrli, P. Bullani, R., Schneider, P., Holler, N., Salomon, D., Hunziker, T., Jean-Hilaire S., Tschoop, J. and French, L.S. (1998) "Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin", Science 282490-282493.
  • Ryo, K., Kamogawa, Y., Ikeda, I., Yamauchi, K., Yonchara, S., Nagata, S. and Hayasahi, N. (2000) "Significance of Fas antigen mediated apoptosis in human fulminant hepatic failure", Am. J. Gastroenterol. 95, 2047-2055.
  • Silvestris, F., Tucci, M., Cafforio, P. and Dammaco, F. (2001) "Fas-L upregulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression", Blood 97, 1155-1164.
  • Andreef, M., Darzynkiewicz, S., Sharpless, T.K., Clarkson, B.D. and Melamed, M.R. (1988) "Discrimination of human leukaemia subtypes by flow cytometer analysis of cellular DNA and RNA", Blood 55, 282-293.
  • Reed, C.J (2000) "Apoptosis and cancer: strategies for integrating programmed cell death", Semin. Hematol. 37(4 suppl. 7), 9-16.
  • Villunger, A., Egle, A. and Marschitz, I. (1997) "Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of rumor-induced suppression of immune surveillance", Blood 90, 12-20.
  • O'Connell, J., O'Sullivan, J.K. and Shanahan, F. (1996) "The fas counterattack: Fas-mediated T cell killing by colon cancer expressing Fas ligand", J. Exp. Med. 184, 1075-1082.
  • Hane, M., Rimoldi, D., Schroter, M., et al. (1996) "Melanoma cell expression of Fas (Apo-1/CD95) ligand: implications for tumor immune escape", Science 274, 1363-1366.
  • Saas, P., Walker, P.R., Hahne, M., et al., (1997) "Fas-ligand expression by astrocytonia in vivo: maintaining immune privilege in the brain?", J. Clin. Invest. 99. 1173-1178.
  • Ito, Y., Monden, M., Takeda, T., Eguchi, H., Umeshita, K., Hagano, H., et al., (2000) "The status of Fas and Fas-ligand expression can predict recurrence of hepatocellular carcinoma", Br. J. Cancer 82, 1211-1217.
  • Reimer, T., Herrming, C., Koczan, D., Ritcher, D., Gerber, B., Kabelitz, D., Friese, K. and Thiesen, H.J. (2000) "FasL:Fas ratio, a prognostic factor in breast carcinoma", Cancer Res. 60, 822-828.
  • Munakata, S., Enomoto, T., Tsujimoto, M., Otsuki, Y., Miwa, H., Kanno, H. and Aozasa, K. (2000) "Expression of Fas ligand and other apoptosis-related genes and their prognostic significance in epithelial ovarian neoplasms", Br. J. Cancer 82, 1446-1452.
  • Mann, B., Gratchev, A., Bohm, C., Hanski, M.L. Foss, H.D., Demel, G., Trojanck, B., Schmidt-Wolf, I., Stem, H., Riccken, E.O., Buhr, H.J. and Hanski, C. (1999) "Fast, is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas", Br. J Cancer 79, 1262-1269.

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