Advanced search
Publication Cover
Leukemia & Lymphoma Volume 43, 2002 - Issue 4
Submit an article Journal homepage
17
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Anti-tumor Activity of Pamidronate in Human Multiple Myeloma

Haruki Kondo Department of Medicine, Division of Hematology and Oncology, Shimizu Kohsei Hospital, 578-1 Ihara-cho, Shimizu-city, Shizuoka 424-0114, Japan
&
Akinori Mori Department of Medicine, Division of Hematology and Oncology, Shimizu Kohsei Hospital, 578-1 Ihara-cho, Shimizu-city, Shizuoka 424-0114, Japan
Pages 919-921 | Published online: 01 Jul 2009

  • Myeloma Aredia Study Group, Berenson, J.R., Lichteostein, A., Porter, L., Dimopoulos, M.A., Bordoni, R., George, S., Lipton, A., Keller, A., Ballester, O., Kovacs, M., Blacklock, H., Bell, R., Simcone, J.F., Reilsma, D.J., Heffernan, M., Seaman, J. and Knight, R.D. (1998) "Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events". Journal of Clinical Oncology 16, 593-602.
  • Abildgaard, N., Rungby, J., GIerup, H., Brixen, K., Kassem, M., Brincker, H., Heickendorff, L., Eriksen, E.E. and Nielsen, J.L. (1998) "Long-term oral pamidronate treatment inhibits osteoclustic bone resorption and bone turnover without affecting osteoblastic function in multiple myeloma". European Journal of Haematology 61, 128-134.
  • Dhodapkar, M.V., Weinstein, R., Tricot, G., Jagannath, S., Parfitt, A.M., Manolagas, S.C. and Barlogie, B. (1998) "Biologic and therapeutic determinants of bone mineral density in multiple myeloma". Leukemia and Lymphoma 32, 121-127.
  • Shipman, C.M., Rogers, M.J., Apperley, J.F., Russel, G.G. and Croucher, P.I. (1997) "Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumor activity", British Journal of Haematology 98, 665-672.
  • Aparicio, A., Gardner, A., Tu, Y., Savage, A., Berensou, J. and Liechtenstein, A. (1998) "In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates", Leukemia 12, 220-229.
  • Shipman, C.M., Vanderkerken, K., Rogers, M.J., Lippitt, J.M., Asosingh, K., Hughes, D.E., Cainp, B.V., Russel, G.G. and Crouchwr, P.I. (2000) "The potent bisphosphonate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma", British Journal of Haematology 111, 283-286.
  • Dhodapkar, M.V., Singh, J., Mehta, J., Passas, a., Desikan, K.R., Perlman, M., Munshi, N.C. and Barlogie, B. (1998) "Anti-myeloma activity of palmidronate in vivo", British Journal of Haematology 103, 530-532.
  • Corso, A., Astori, C., Orlandi, E., Zappasodi, P., Arcaini, L. and Bernasconi, C. (1999) "Transient response of myeloma clone to pamidronate therapy", Haematologica 84, 759-760.
  • Greipp, P.R. (1992) "Advances in the diagnosis and management of myeloma", Seminars in Hematology 29, 24-45.
  • Shipman, C.M., Croucher, P.I., Russell, G.G., Helfrich, M.H. and Rogers, M.J. (1998) "The bisphosphonate incarbonate (YMI75) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway", Cancer Research 58, 5294-5297.
  • Kunzraann, V., Bauer, E., Feurle, J., Weißinger, R., Tony, H.-P. and Wilhelm, M. (2000) "Stimulation of -?d T cells by aminobisphospbonates and induction of antiplasma cell activity in multiple myeloma". Blood 96, 384-392.
  • Buckman, R., Cuzick, J. and Galton, D.A. (1982) "Long-term survival in myelmatosis A report to the MRC working party on leukaemia in adults", British Journal of Haematology 52, 589-599.
  • Weber, D.M., Dimopoulos, M.A., Moulopoulos, L.A., Delasalle, K.B., Smith, T.L. and Alexanian, R. (1996) "Prognostic features in asymptomatic multiple myeloma", Blood 88, 390a.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.