272
Views
64
CrossRef citations to date
0
Altmetric
Research Article

The Role of Interleukin 13 in Classical Hodgkin Lymphoma

, &
Pages 1203-1210 | Published online: 01 Jul 2009

  • Drexler, H.G. (1992) "Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy material". Leukemia and Lymphoma 8. 283-313.
  • Drexler, H.G. (1993 ) "Recent results on the biology of Hodgkin and Reed-Stemberg cells. II. Continuous cell lines", Leukemia and Lymphoma 9,1- 25.
  • Kapp, U., Yeh, W.C., Patterson, B., Elia, A.J., Kagi, D., Ho, A. Hessel, A. Tipsword, M., Williams, A., Mirtsos, C., Itie, A., Moyle, M. and Mak, T.W. (1999) "nterleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed Stemberg cells". Journal of Experimental Medicine 189. 1939-1945
  • Skinnider, B.F. Elia, A.J., Gascoyne, R.D., Trumper, L.H., von Bonin, R. Kapp. U., Patterson, B., Snow, B.E. and Mak, T.W. (2001) "lntereleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed - Sternberg cells of Hodgkin lymphoma". Blood 97. 250-255.
  • Zurawski, G. and de Vries, J.E. (1994) "Interleukin 13. an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells". Immunology Today 15, 19-26.
  • de Waal Malefyt, R. Abrams, J.S., Zurawski, S.M., Lecron, J.-C, Mohan-Peterson, S., Sanjanwala, B., Bennett, B., Silver, J., de Vries, J.E. and Yssel, H. (1995) "Differential regulation of IL-13 and IL-4 production by human CD8 + and CD4 + Th0. Th1 and Th2 T cell clones and EBV-transformed B cells", International Immunology T, 1405-1416.
  • Burd, P.R., Thompson, W.C., Max, E.E. and Mills, F.C. (1995) "Activated mast cells produce interleukin 13". Journal of Experimental Medicine 181. 1373-1380.
  • Ochensherger, B., Daepp, G.C., Rihs, S. and Dahinden, C.A. (1996) "Human blood basophils produce interleukin-13 in response to IgEreceptor-dependent and -independent activation", Blood 88. 3028-3037.
  • Kindler, V. Matthes, T., Jeannin, P. and Zubler, R.H. (1995) "Interleukin-2 secretion by human B lymphocytes occurs as a late event and requires additional stimulation after CD40 cross-linking". European Journal of Immunology 25, 1239-1243.
  • Punnonen, J., Aversa, G., Cocks, B.C., McKenzie, A.N.J., Menon, S., Zurawski, G., de Waal Malefyl, R. and de Vries, J.F., (1993) "Interleukin 13 induces interleukin 4-independent lgG4 and IgE synthesis and CD23 expression by human B cells". Proceeding of the National Academy of Sciences of the USA 90, 3730-3734.
  • Mckenzie, A.N.J., Culpepper, J.A., de Waal Malefyt, R., Briere, R. Punnonen, J., Aversa, G., Sato, A., Dang, W., Cocks, B.C., Menon, S., de Vries, J.E., Banchereau, J. and Zurawski, G. (1993) "Interleukin 13, a T-cell derived cytokine that regulates human monocyte and B-cell function", Proceedings of the National Academy of Sciences of the USA 90, 3735-3739.
  • Defrance, T., Carayon, P., Billian, G., Guillemot, J-C., Minty, A., Caput, D. and Ferrara, P. (1994) "Interleukin 13 is a B cell stimulating factor". Journal of Experimental Medicine 179. 135-143.
  • Lomo, J., Blomhoff, H.K., Jacobsen, S.F., Krajewski, S., Reed, J.C. and Smeland, E.B. (1997) "Interleukin-13 in combination with CD40 ligand potently inhibits apoptosis in human B lymphocytes: upregulation of Bcl-xL and Mci-I". Blood 89,4415-4424.
  • Minty, A, Chalon, P., Derocq, J.M., Dumont, X., Guillemot, J.-C., Kaghad, M., Labil, C., Leplatois, P., Liauzun, P., Miloux, B., Minty, C., Casellas, P. Loison, G., Lupker, J., Shire, D., Herrara, P. and Caput, D. (1993) "Interleukin-13 is a new human lymphukine regulating inflammatory and immune responses". Nature 362. 248 -250.
  • de Waal Malefyt, R., Figdor, C.G., Huijbens, R., Mohan-Peterson, S. Bennett, B., Culpepper, J., Dang, W., Zurawski, G. and de Vries, J.E. (1993) "Effects of IL-13 on phenotype. cytokine production, and cytotoxic function of human monocytes". Journal of Immunology 151, 6370-6381.
  • Graher, P., Grctener, D., Herren, S., Aubry, J.P., Elson, G., Poudrier, J., Lecoanet-Henchoz, S., Alouanu S., Losberger, C. Bonnefoy, J.Y. Kosco-Vilbois, M.H. and Gauchat, J.F. (1998) "The distribution of IL-13 receptor alphal expression on B cells, T cells and monocytes and its regulation by IL-13 and IL.-4", European Journal of Immunology 28, 4286-4298.
  • Bonecchi, R., Sozzani, S., Stine, J.T., Luini, W., D'Amico, G., Allavena, P., Chantry, D. and Mantovani, A. (1998) "Divergent effects of Interleukin-4 and interferon-gamma on macrophagederived chemokine production: an amplification circuit of polarized T helper 2 responses". Blood 92, 2668-2671.
  • Andrew, D.P., Chang, M.S., McNinch, J., Wathen, S.T., Rihanek, M. Tseng, J. Spellberg, J.P. and Elias, [1]. C.G. (1998) "STCP-I (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13", Journal of Immunology 161, 5027- 5038.
  • Hoeck, J. and Woisetschlager, M. (2001) "STAT6 mediates cotaxin-1 expression in IL-4 or TNF-alpha-induced tibroblasts". Journal of Immunology 166. 4507-4515.
  • Sallusto, F., Lenig, D.'Mackay, C.R. and Lanzavecchia, A. (1998) "Flexible programs of chemokine receptor expression on human polarized T helper I and 2 lymphocytes". Journal of Experimental Medicine 187, 875-883.
  • Kitaura, M., Nakajima, T., Imai, T., Harada, S., Combadiere, C., Tiffany, H.L., Murphy, P.M. and Yoshie, O. (1996) "Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine. and identification of a specific eosinophil eotaxin receptor. CC chemokine receptor 3". Journal of Biological Chemistry 271. 7725-7730.
  • Luttman, W., Matthiesen, T., Matthys, H. and Virchow, Jr, J.C. (1999) "Synergistic effects of interleukin-4 or interleukin-13 and tumor necrosis factor-á on eosinophil activation in vitro". American Journal of Respiratory Cell and Molecular Biology 20, 474 480.
  • Zhu, Z., Homer, R.J., Wang, Z., Chen, Q., Geba, G.P. Wang. J., Zhang, Y. and Elias, J.A. (1999) "Pulmonary expression of inlerleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production". Journal of Clinical Investigation 103, 779-788.
  • Chianuuonte, M.G., Donaldson, D.D., Cheever, A.W. and Wynn, T.A. (1999) "An 11.-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response". Journal of Clinical Investigation 104, 777-785.
  • Nelms, K., Keegan, A.D., Zamorano, J., Ryan, J.J. and Paul, W.F., (1999) "The IL.-4 receptor: signaling mechanisms and biologic functions". Annual Review of Immunology 17, 701 -738
  • Aman, M.J., Tayebi, N., Obiri, N.I., Puri, R.K., Modi, W.S. and Leonard, W.J. (1996) "cDNA cloning and characterisation of the human interlcukin 13 receptor a chain". Journal of Biological Chemistry 271, 29265-29270.
  • Caput, D., Laurent, P., Kaghad, M., Lelias, J.-M. Lefort, S., Vita, N. and Perrara, P. (1996) "Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the 11.-5 receptor a chain". Journal of Biological Chemistry 271. 16921-16926.
  • Feng, N., Lugli, S.M., Schnyder, B. Gauchat, J.F. Graber, P., Schlagenhauf, E., Schnarr, B. Wiederkehr-Adam, M., Duschl. A. Heim, M.H., Lutz, R.A. and Moser, R. (1998) "The interleukin4/interleukin-1.3 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2". Laboratory Investigation 78, 591-602.
  • Kawakami, K., Taguchi, J., Murata, T. and Puri, R.K. (2001) "The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway". Blood 97. 2673-2679.
  • Leonard, W.J. and O'Shea, J.J. (1998) "JAKs and, STATs: biological implications". Annual Review of Immunology 16, 293-322.
  • Wurster, A.L., Tanaka, T. and Grusby, M.J. (2000) "The biology of Stat4 and Stat6", Oncogene 19, 2577-2584.
  • Takeda, K., Tanaka, T. Shi, W., Matsumoto, M., Minami, M., Kashiwamura, S-L. Nakanishi, K., Yoshida, N., Kishimoto, T. and Akira, S. (1996) "Essential role of Stato in IL-4 signaling". Nature 380, 627-630.
  • Shimoda, K., van Deursen, J., Sangster, M.Y., Sarawar, S.R., Carson, R.T., Tripp, R.A., Chu, C., Quelle, F.W., Nosaka, T., Vignali, D.A.A., Doheny, P.C., Grosveld, G., Paul, W.h. and lble, J.N. (1996) "Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stato gene". Nature 380. 630-633.
  • Takeda, K. Kamanaka, M., Tanaka, T. Kishimoto, T. and Akira, S. (1996) "Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice". Journal of Immunology 157. 3220-3222.
  • Skinnider, B.F., Elia, A.J., Gascoyne, R.D., Patterson, B., Trumper, L., Kapp, U. and Mak, T.W. (2002) "Signal transducer and activator of transcription 6 is frequently activated in Hudgkin and ReedStemberg cells of Hodgkin lymphoma". Blood 99. 618-626.
  • Ohshima, K., Akaiwa. M-. Umeshila, R., Suzumiya, J., Izuhani, K. and Kikuchi, M. (2001) "Interleukin-13 and interleukin-13 receptor in Hodgkin's disease: possible autoerinc mechanism and involve ment in fibrosis". Histopathology 38, 368-375.
  • Herbst, H., Foss, H.D., Samol, J., Araujo, L. Klotzbach, H., Krause, H., Agathanggelou, A., Niedobitek, G. and Stein, H. (1996) "Frequent expression of interleukin-10 by Epstein-Barr virusharboring tumor cells of Hodgkin's disease". Blood 87, 2918-2929.
  • Dukers, D.F., Jaspars, L.H., Vos, W., Oudejans, J.J., Hayes, D., Cillessen, S., Middeldorp, J.M. and Meijer, C-J. (2000) "Quantitative immunohistochemical analysis of cytokine profiles in Epstein-Barr virus-positive and -negative cases of Hodgkin's disease". Journal of Pathology 190, 143 149.
  • Teruya-Feldstein, J., Jaffe, E.S., Bunt P.R., Kingma, D.W., Setsuda, J.E. and Tosato, G. (1999) "Differential chemokine expression in tissues involved by Hodgkin's disease: direct correlation of eotaxin expression and tissue eosinophilia". Blood 93, 2463-2470
  • van den Berg, A., Visser, L and Poppema, S. (1999) "High expression of the CC chemokine TARC in Reed-Stemberg cells. A possible explanation for the characteristic T-cell infiltrate in Hodgkin's lymphoma", American Journal of Pathology 154, 1685-1691.
  • Jundt, F., Anagnosiopoulos, I., Bommert, K., Emmerich, F., Muller, G., Foss, H.D., Royer, H.D., Stein, H. and Dorken, B. (1999) "Hodgkin/Reed-Stemberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophits". Blood 94. 2065-2071.
  • Sekiya, T., Miyamasu, M., lmanishi, M., Yamada, H., Nakajima, T. Yamaguchi, M., Fujisawa, T., Pawankar, R., Sano, Y. Ohta, K., Ishii, A., Monta, Y., Yamamoto, K., Matsushima, K., Yoshie, O. and Hirai, K. (2000) "lnducible expression of a Th2-lype CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells". Journal of Immunology 165, 2205 2213.
  • Mathew, A., MacLean, J.A., DeHaan, E., Tager, A.M., Green, E.H. and Luster, A.D. (2001) "Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation". Journal of Experimental Medicine 193, 1087-1096.
  • McKenzie, G.J., Bancroft, A., Grenics, R.K. and McKenzie, A.N.J. (1998) "A distinct role for interleukin-13 in Th2-cell-mediated immune responses". Current Biology 8, 339-342.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.