Advanced search
Publication Cover
Leukemia & Lymphoma Volume 44, 2003 - Issue 4
Submit an article Journal homepage
115
Views
28
CrossRef citations to date
0
Altmetric
Research Article

Clinico-hematologic Features of Myelodysplastic Syndrome Presenting as Isolated Thrombocytopenia: An Entity with a Relatively Favorable Prognosis

Goro Sashida First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
TOMO-IKU Takaku First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Nahoko Shoji First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Jiroh Nishimaki First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Yoshikazu Ito First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Keisuke Miyazawa First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Yukihiko Kimura First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
,
Junko H. Ohyashiki First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
&
Kazuma Ohyashiki First Department of Internal Medicine, and Division of Intractable Disease Therapeutic Center, Tokyo Medical University, Tokyo 160-0023, Japan
 show all
Pages 653-658 | Published online: 01 Jul 2009

  • Bennett, J.M., Catovsky, D., Daniel, M.T., Flandrin, G., Galton, D.A.G., Gralnick, H.R. and Sultan, C. (1982) "Proposal for the classification of the myelodysplastic syndrome", Br, J. Haematol. 51, 189-199.
  • Koeffler, H.P. (1986) "Myelodysplastic syndromes (preleukemia)", Semin. Hematol. 23, 284-299.
  • Tricot, C., Criel, A. and Verwilghen, R.L. (1982) "Thrombocytopenia as presenting symptom of preleukemia in 3 patients", Scand, J. Haematol. 28, 243-250.
  • Mitsutani, S., Kohriyama, T., Kamio, M. and Saitoh, T. (1987) "Isolated thrombocytopenia as presenting symptom of MDS", Jpn J. Clin. Haematol. 28, 945-950.
  • Najean, Y. and Lecompte, T. (1989) "Chronic pure thrombocytopenia in elderly patients: an aspect of the myelodysplastic syndrome", Cancer 64, 2506-2510.
  • Menke, D.M., Otero, G.C., Cockerill, K.J., Jenkins, R.B., Noel, P. and Pierre, R.V. (1992) "Refractory thrombocytopenia: a myelodysplastic syndrome that may mimic immune thrombocytopenic purpura", Am, J. Clin. Pathol. 98, 502-510.
  • Imoto, S., Hayashi, Y., Matsui, T., Murayama, T., Iwama, N., Matsuoka, H., Nagata, A., Itoh, H. and Chihara, K. (1996) "Refractory thrombocytopenia with chromosome 11q23 abnormality", Ann. Hematol. 73, 99-102.
  • Jondeau, K., Bouscary, D., Viguie, F., Picard, F., Melle, J., Lopez, I., Roupie, M.F. and Dreyfus, F. (1996) "Thrombocytopenia and abnormal megakaryopoiesis associated with abnormality of chromosome 1p34 in myelodysplastic syndromes", Leukemia 10, 1692-1695.
  • Michels, S., Chan, W., Jakubowski, D. and Vogler, R. (1990) "Unclassifiable myelodysplastic syndrome: a study of sixteen cases with a proposal for a new subtype", Lab. Investig. 62, 67.
  • Rosati, S., Mick, R., Xu, F., Stonys, H., Le Beau, M.M., Larson, R. and Vardiman, J.W. (1996) "Refractory cytopenia with multilineage dysplasia: further characterization of an 'Unclassifiable" myelodysplastic syndrome", Leukemia 10, 20-26.
  • Shimamoto, T., Iguchi, T., Ando, K., Katagiri, T., Tauchi, T., Ito, Y., Yaguchi, M., Miyazawa, K., Kimura, Y., Masuda, M., Mizoguchi, H. and Ohyashiki, K. (2001) "Successful treatment with cyclosporin A for myelodysplastic syndrome with erythroid hypoplasia which is associated with T-cell receptor gene rearrangements", Br, J. Haematol. 114, 358-361.
  • Nagai, K., Matsuo, T., Atogami, S., Moriuchi, Y., Yoshida, Y., Muriyama, K. and Tomonaga, M. (1992) "Remission with morphological myelodysplasia in de novo acute myeloid leukaemia: implication for early relapse", Br, J. Haematol. 81, 33-39.
  • Mitelman, F., ed. (1995) International System for Cytogenetic Nomenclature: Guidelines for Cancer Cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature (Karger, Basel).
  • Harris, N.L., Jaffe, E.S., Diebold, J., Flandrin, G., Hermelink, H.K.M., Vardiman, J., Lister, T.A. and Bloomfield, C.D. (1999) "World health organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the clinical advisory committee meeting", J. Clin. Oncol. 17, 3835-3849.
  • Greenberg, P., Cox, C., Le Beau, M.M., Fenaux, P., Morel, P., Sanz, G., Sunz, M., Vallepsi, T., Hamblin, T., Oscier, D., Ohyashiki, K., Toyama, K., Aul, C., Mufti, G. and Bennett, J. (1997) "International scoring system for evaluating prognosis in myelodysplastic syndromes", Blood 89, 2079-2088.
  • Asano, H., Ohashi, H., Ichihara, M., Kinoshita, T., Murate, T., Kobayashi, M., Saito, H. and Hotta, T. (1994) "Evidence for nonclonal hematopoietic progenitor cell populations in bone marrow of patients with myelodysplastic syndromes", Blood 84, 588-594.
  • Anan, K., Ito, M., Misawa, M., Ohe, Y., Kai, S., Kohsaki, M. and Hara, H. (1995) "Clonal analysis of peripheral blood and haemopoietic colonies in patients with aplastic anaemia arid refractory anaemia using the polymorphic short tandem repeat on the human androgen-receptor (HUMARA) gene", Br, J. Haematol. 89, 838-844.
  • Suzuki, H., Asano, H., Ohashi, H., Kinoshita, T., Murate, T., Saito, H. and Hotta, T. (1999) "Clonality analysis of refractory anemia with ring sideroblasts: simultaneous study of clonality and cytochemistry of bone marrow progenitors", Leukemia 12, 130-134.
  • Sashida, G., Ohyashiki, J.H., Itoh, Y. and Ohyashiki, K. (2002) "Monoclonal constitution in neutrophils detected by the PCR-based human androgen receptor gene assay in a subset of idiopathic thrombocytopenic purpura patients", Leuk. Res. 26, 825-830.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.