Imbalance Between Apoptosis and Telomerase Activity in Myelodysplastic Syndromes: Possible Role in Ineffective Hemopoiesis

References

• Dormer, P., Schalhorn, A., Wiliams, W. and Hershko, C. (1987) "Erythroid and myeloid maturation patterns related to progenitor assessment in the myelodysplastic syndromes", British Journal of Haematology 67, 61–66.
   PubMed Web of Science ®Google Scholar
• Yoshida, Y. (1995a) "Hypothesis: apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndromes", Leukemia 7, 144–146.
   Web of Science ®Google Scholar
• Yoshida, Y, Anzai, N. and Kawabata, H. (1995b) "Apoptosis in myelodysplasia: a paradox or a paradigm", Leukemia Research 19, 887–891.
   PubMed Web of Science ®Google Scholar
• Shimazaki, K., Ohshima, K., Suzumiya, J., Kawasaki, C. and Kikuchi, M. (2000) "Evaluation of apoptosis as a prognostic factor in myelodysplastic syndromes", British Journal of Haematology 110, 584–590.
   PubMed Web of Science ®Google Scholar
• Raff, M.C. (1992) "Social controls on cell survival and cell death", Science 356, 397–400.
   Google Scholar
• Cohen, G.M. (1997) "Caspases: the executioners of apoptosis", Biochemistry Journal 326, 1–16.
   PubMed Web of Science ®Google Scholar
• Los, M., Wesselborg, S. and Schulze-Osthoff, K. (1999) "The role of caspases in development, immunity, and apoptosis signal transduction: lessons from knockout mice", Immunity 10, 629–639.
   PubMed Web of Science ®Google Scholar
• Garcia-Calvo, M., Peterson, E.P., Leiting, B., Ruel, R., Nicholson, D.W. and Thornbeny, NA. (1998) "Inhibition of human caspases by peptide-based and macromolecular inhibitors", Journal of Biological Chemistry 273, 32608–32613.
   PubMed Web of Science ®Google Scholar
• Liu, X.S., Zou, H., Slaughter, C. and Wang, X.D. (1997) "DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis", Cell 89, 175–184.
   PubMed Web of Science ®Google Scholar
• Bouscary, D., Chen, Y.L., Guesnu, M., Picard, F., Viguier, F., Lacombe, C., Dreyfus, F. and Fontenay-Roupie, M. (2000) "Activity of the caspase-3/CPP32 enzyme is increased in early stage myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro", Experimental Hematology 28, 784–791.
   PubMed Web of Science ®Google Scholar
• Boudard, D., Sordet, 0., Vasselon, C., Revol, V., Bertheas, M.F., Freyssenet, D., Viallet, A., Piselli, S., Guyotat, D. and Campos, L. (2000) "Expression and activity of caspases 1 and 3 in myelodysplastic syndromes", Leukemia 14, 2045–2051.
   Google Scholar
• Vaziri, H. and Benchimol, S. (1998) "Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span", Current Biology 8, 279–282.
   PubMed Web of Science ®Google Scholar
• Luban, N.L. (1998) "Hemolytic disease of the newborn: progenitor cells and late effectors", New England Journal of Medicine 338, 830 —831.
   PubMed Web of Science ®Google Scholar
• Kataoka, H., Tahara, H., Watanabe, T., Sugawara, M., Ide, T., Goto, M., Furuichi, Y. and Sugimoto, M. (1997) "Immortalization of immunologically committed Epstein—Barr virus-transformed human B-lymphoblastoid cell lines accompanied by a strong telomerase activity", Differentiation 62, 203–211.
   PubMed Web of Science ®Google Scholar
• Seol, J.G., Kim, ES., Park, W.H., Jung, C.W., Kim, B.K. and Lee, Y.Y. (1998) "Telomerase activity in acute myelogenous leukemia: clinical and biological implications", British Journal of Haemato-logy 100, 156–165.
   PubMed Web of Science ®Google Scholar
• Feng, J., Funk, W.D., Wang, S.S., Weinrich, S.L., Avilion, A.A., Chiu, C.P., Adams, R.R., Chang, E., Allsopp, R.C. and Villeponteau, B. (1995) "The RNA component of human telomerase", Science 269, 1236–1241.
   PubMed Web of Science ®Google Scholar
• Nakamura, TM., Morin, GB., Chapman, KB., Weinrich, Si., Andrews, W.H., Linger, J., Harley, C.B. and Cech, T.R. (1997) "Telomerase catalytic subunit homologs from fission yeast and human", Science 277, 955–959.
   PubMed Web of Science ®Google Scholar
• Weinrich, S.L., Pruzan, R., Ma, L., Ouellette, M., Tesmer, V.M., Holt, SE., Bodnar, A.G., Lichtsteiner, S., Kim, NW., Trager, LB., Taylor, RD., Carlos, R., Andrews, W.H., Wright, WE., Shay, LW., Harley, C.B. and Morin, G.B. (1997) "Reconstitution on human telomerase with the template RNA component hTR and the catalytic protein subunit hTR", Nature Genetics 17, 498–502.
   PubMed Web of Science ®Google Scholar
• Hiyama, E., Hiyama, K., Yokoyama, T. and Shay, LW. (2001) "Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues", Neoplasia 3, 17–26.
   PubMed Web of Science ®Google Scholar
• Dreyfuss, G., Matunis, M.J., Piriol-Roma, S. and Burd, C.G. (1993) "hnRNP proteins and the biogenesis of mRNA [Review]", Annual Review of Biochemistry 62, 289–321.
   PubMed Web of Science ®Google Scholar
• McKay, S.J. and Cooke, H. (1992) "hnRNP A2/B1 binds specifically to single stranded vertebrate telomeric repeat TTAGGG", Nucleic Acids Research 20, 6461–6464.
   PubMed Web of Science ®Google Scholar
• Kattnna, H., Fujimoto, M., Fujiwara, M., Matsui, M., Horiguchi, H., Hamasald, M. and Satoh, H. (2001) "Interaction of hnRNP A2/B1 isoforms with telomeric ssDNA and the in vitro function", Biochemical and Biophysical Research Communication 280, 625–630.
   PubMed Web of Science ®Google Scholar
• Tockman, M.S., Mulshine, J.L., Piantadosi, S., Erozan, Y.S., Gupta, P.K., Ruckdeschel, IC., Taylor, P.R., Zhukov, T., Zhou, W., Qiao, Y. and Yao, S. (1997) "Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression", Clinical Cancer Research 3, 2237–2246.
   PubMed Web of Science ®Google Scholar
• Tockman, US., Gupta, P.K., Myers, J.D., Frost, J.K., Baylin, S.B., Gold, E.B., Chase, A.M., Wilkinson, PH. and Mulshine, J.L. (1998) "Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: a new approach to early lung cancer detection", Journal of Clinical Oncology 6, 1685–1693.
   Google Scholar
• Bennett, J.M., Catovsky, D., Daniel, MT., Flandrin, G., Galion, D.A.G. and Gralnick, RR. (1982) "Proposals for the classification of the myelodysplastic syndromes", British Journal of Haematology 51, 189–199.
   PubMed Web of Science ®Google Scholar
• Third MIC Cooperative Study Group (1988) "Recommendations for a morphologic, immunologic, and cytogenetic (1V1IC) working classification of the primary and therapy-related myelodysplastic disorders. Report of the workshop held in Scottsdale, Arizona, USA, on February 23-25, 1987", Cancer Genetics and Cytogenetics 32, 1–10.
   PubMed Web of Science ®Google Scholar
• Varela, B.L., Chuang, C., Woll, J.E. and Benett, J.M. (1985) "Modifications in the classification of primary myelodysplastic syndromes: the addition of a scoring system", Hematological Oncology 3, 55–63.
   PubMed Web of Science ®Google Scholar
• Raza, A., Grezer, S., Mundle, S., Gao, X.Z., Alvi, S., Borok, R., Rifkin, S., Iftikhar, A., Shetty, V. and Parcharidou, A. (1995) "Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syn-dromes", Blood 86, 268–276.
   PubMed Web of Science ®Google Scholar
• Lepelley, P., Campergue, L., Grardel, N., Preudhonune, C., Cosson, A. and Fenaux, P. (1996) "Is apoptosis a massive process in myelodysplastic syndromes?", British Journal of Haematology 95, 368–371.
   PubMed Web of Science ®Google Scholar
• Ohyashiki, K., Iwama, H., Yahata, N., Tauchi, T., Kawakubo, K., Shimamoto, T. and Ohyashiki, J.H. (2001) "Telomere dynamics in myelodysplastic syndromes and acute leukemic transformation", Leukemia and Lymphoma 42, 291–299.
   PubMed Web of Science ®Google Scholar
• Li, B., Yang, J., Andrews, C., Chen, Y.X., Toofanfard, P., Huang, R.W., Horvath, E., Chopra, H., Raza, A. and Preisler, H.D. (2000) "Telomerase activity in preleukemia and acute myelogenous leukemia", Leukemia and Lymphoma 36, 579–587.
   PubMed Web of Science ®Google Scholar
• Engelhardt, M., Mackenzie, K., Drullinsky, P., Silver, R.T. and Moore, MA. (2000) "Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-ex vivo culture", Cancer Research 60, 610–617.
   PubMed Web of Science ®Google Scholar
• Sueoka, E., Sueoka, N., Goto, Y, Matsuyama, S., Nishimura, H., Sato, M., Fujimura, S., Chiba, H. and Fujiki, H. (2001) "Heterogeneous nuclear ribonucleoprotein B1 as early cancer biomarker for occult cancer of human lungs and bronchial dysplasia", Cancer Research 61, 1896–1902.
   PubMed Web of Science ®Google Scholar
• Rajapaska, R., Ginzton, N., Rott, L.S. and Greenberg, P.L. (1996) "Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells", Blood 88, 4275–4287.
   PubMed Web of Science ®Google Scholar