Analysis of FAS (CD95) Gene Mutations in Higher-Grade Transformation of Follicle Center Lymphoma

References

• Oehm, A., Behrmann, I., Falk, W., Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J., Trauth, B.C., et al. (1992) "Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen", J. Biol. Chem. 267, 10709–10715.
   PubMed Web of Science ®Google Scholar
• Suda, T., Takahashi, T., Golstein, P. and Nagata, S. (1993) "Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family", Cell 75, 1169–1178.
   PubMed Web of Science ®Google Scholar
• Nagata, S. and Golstein, P. (1995) "The Fas death factor", Science 267, 1449–1456.
   PubMed Web of Science ®Google Scholar
• Nagata, S. (1997) "Apoptosis by death factor", Cell 88, 355–365.
   PubMed Web of Science ®Google Scholar
• Martinez-Valdez, H., Guret, C., de Bouteiller, 0., Fugier, I., Banchereau, J. and Liu, Y.J. (1996) "Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Box but not the survival gene bc1-2", J. Exp. Med. 183, 971–977.
   PubMed Web of Science ®Google Scholar
• Muschen, M., Re, D., Jungnickel, B., Diehl, V, Rajewsky, K. and Kuppers, R. (2000) "Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction", J. Exp. Med. 192, 1833–1840.
   PubMed Web of Science ®Google Scholar
• Watanabe-Fukunaga, R., Brannan, CI., Copeland, N.G., Jenkins, N.A. and Nagata, S. (1992) "Lymphoproliferation disorder in mice explained by defects in Fos antigen that mediates apoptosis", Nature 356, 314–317.
   PubMed Web of Science ®Google Scholar
• Fisher, G.H., Rosenberg, F.J., Straus, SE., Dale, J.K., Middleton, L.A., Lin, A.Y., Strober, W., Lenardo, M.J. and Puck, J.M. (1995) "Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome", Cell 81, 935–946.
   PubMed Web of Science ®Google Scholar
• Rieux-Laucat, F., Le Deist, F., Hivroz, C., Roberts, LA., Debatin, K.M., Fischer, A. and de Villartay, J.P. (1995) "Mutations in Fas associated with human lymphoproliferative syndrome and auto-immunity", Science 268, 1347–1349.
   PubMed Web of Science ®Google Scholar
• Muschen, M., Warskulat, U. and Beckmann, M.W. (2000) "Defining CD95 as a tumor suppressor gene", J. MoL Med. 78, 312–325.
   PubMed Web of Science ®Google Scholar
• Boulanger, E., Rieux-Laucat, F., Picard, C., Legall, M., Sigaux, F., Clauvel, J.P., Oksenhendler, E., Le Deist, F. and Meignin, V. (2001) "Diffuse large B-cell non-Hodgkin's lymphoma in a patient with autoinunune lymphoproliferative syndrome", Br. J. HaematoL 113, 432–434.
   PubMed Web of Science ®Google Scholar
• Xerri, L., Carbuccia, N., Parc, P. and Birg, F. (1995) "Search for rearrangements and/or allelic loss of the fas/APO-1 gene in 101 human lymphomas", Am. J. Clin. Pathol. 104, 424–430.
   PubMed Web of Science ®Google Scholar
• Peters, A.M., Kohfink, B., Martin, H., Griesinger, F., Wormann, B., Gahr, M. and Roesler, J. (1999) "Defective apoptosis due to a point mutation in the death domain of CD95 associated with autoimmune lymphoproliferative syndrome, T-cell lymphoma, and Hodgkin's disease", Exp. HematoL 27, 868–874.
   PubMed Web of Science ®Google Scholar
• Landowski, T.H., Qu, N., Buyuksal, I., Painter, J.S. and Dalton, W.S. (1997) "Mutations in the Fos antigen in patients with multiple myeloma", Blood 90, 4266–4270.
   PubMed Web of Science ®Google Scholar
• Delehanty, L.L., Payne, J.A., Farrow, S.N., Brown, R. and Champion, ER. (1997) "Apoptosis in a Fas-resistant, T-cell receptor-sensitive human leukaemic T-cell clone", Immunology. 90, 383–387.
   PubMed Web of Science ®Google Scholar
• Gronbaek, K., Straten, PT., Ralfkiaer, E., Ahrenkiel, V, Andersen, M.K., Hansen, N.E., Zeuthen, J., Hou-Jensen, K. and Guldberg, P. (1998) "Somatic Fos mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity", Blood 92, 3018–3024.
   PubMed Web of Science ®Google Scholar
• Beltinger, C., Kurz, E., Bohler, T., Schrappe, M., Ludwig, W.D. and Debatin, K.M. (1998) "CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia", Blood 91, 3943–3951.
   PubMed Web of Science ®Google Scholar
• Tamiya, S., Etoh, K., Suzushima, H., Takatsuld, K. and Matsuoka, M. (1998) "Mutation of CD95 (Fas/Apo-1) gene in adult T-cell leukemia cells", Blood 91, 3935–3942.
   PubMed Web of Science ®Google Scholar
• Lee, S.H., Shin, M.S., Park, W.S., Kim, S.Y., Dong, S.M., Pi, J.H., Lee, H.K., Kim, H.S., Jang, J.J., Kim, CS., Kim, S.H., Lee, J.Y. and Yoo, N.J. (1999) "Alterations of Fos (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder", Cancer Res. 59, 3068–3072.
   PubMed Web of Science ®Google Scholar
• Lee, S.H., Shin, M.S., Park, W.S., Kim, S.Y., Kim, H.S., Han, J.Y., Park, G.S., Dong, S.M., Pi, J.H., Kim, CS., Kim, S.H., Lee, J.Y. and Yoo, N.J. (1999) "Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer", Oncogene 18, 3754–3760.
   PubMed Web of Science ®Google Scholar
• Plumas, J., Jacob, MC., Chaperot, L., Molens, J.P., Sotto, J.J. and Bensa, J.C. (1998) "Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis", Blood 91, 2875–2885.
   PubMed Web of Science ®Google Scholar
• Landowski, T.H., Gleason-Guzman, M.C. and Dalton, W.S. (1997) "Selection for drug resistance results in resistance to Fas-mediated apoptosis", Blood 89, 1854–1861.
   PubMed Web of Science ®Google Scholar
• Friesen, C., Herr, I., Kranuner, P.H. and Debatin, K.M. (1996) "Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug- induced apoptosis in leukemia cells", Nat. Med. 2, 574–577.
   PubMed Web of Science ®Google Scholar
• Acker, B., Hoppe, R.T., Colby, TN., Cox, R.S., Kaplan, H.S. and Rosenberg, S.A. (1983) "Histologic conversion in the non-Hodgkin's lymphomas", J. Clin. Oncol. 1, 11–16.
   PubMed Web of Science ®Google Scholar
• Horning, S.J. and Rosenberg, S.A. (1984) "The natural history of initially untreated low-grade non-Hodgkin's lymphomas", N. EngL J. Med. 311, 1471–1475.
   PubMed Web of Science ®Google Scholar
• Harris, N.L., Jaffe, ES., Stein, H., Banks, P.M., Chan, J.K., Cleary, ML., Delsol, G., De Wolf-Peeters, C., Falini, B. and Gatter, K.C. (1994) "A revised European—American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]", Blood 84, 1361–1392.
   PubMed Web of Science ®Google Scholar
• Jin, L., Underhill, PA., Doctor, V, Davis, R.W., Shen, P., Cavalli-Sforza, L.L. and Oefner, P.J. (1999) "Distribution of haplotypes from a chromosome 21 region distinguishes multiple prehistoric human migrations", Proc. Natl Acad. Sci. USA 96, 3796–3800.
   PubMed Web of Science ®Google Scholar
• Huang, Q.R., Morris, D. and Manolios, N. (1997) "Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene", MoL Immunol. 34, 577–582.
   PubMed Web of Science ®Google Scholar
• Armitage, J.0., Sanger, W.G., Weisenburger, D.D., Harrington, D.S., Linder, J., Bierman, P.J., Vose, J.M. and Purtilo, D.T. (1988) "Correlation of secondary cytogenetic abnormalities with histologic appearance in non-Hodgkin's lymphomas bearing t(14;18)(q32;q21)", J. Nall Cancer Inst. 80, 576–580.
   PubMed Web of Science ®Google Scholar
• Richardson, ME., Chen, Q.G., Filippa, D.A., Offit, K., Hampton, A., Koduru, P.R., Jhanwar, S.C., Lieberman, PH., Clarkson, B.D. and Chaganti, R.S. (1987) "Intermediate- to high-grade histology of lymphomas carrying t(14;18) is associated with additional nonrandom chromosome changes", Blood 70, 444–447.
   PubMed Web of Science ®Google Scholar
• Yunis, J.J., Frizzera, G., Oken, UM., McKenna, J., Theologides, A. and Arnesen, M. (1987) "Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer", N. Engl. J. Med. 316, 79–84.
   PubMed Web of Science ®Google Scholar
• Lee, J.T., Innes, D.J., Jr and Williams, M.E. (1989) "Sequential bc1-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma", J. Clin. Investig. 84, 1454–1459.
   PubMed Web of Science ®Google Scholar
• Yano, T., Jaffe, ES., Longo, D.L. and Raffeld, M. (1992) "MYC rearrangements in histologically progressed follicular lymphomas", Blood 80, 758–767.
   PubMed Web of Science ®Google Scholar
• Sander, C.A., Yano, T., Clark, H.M., Harris, C., Longo, DL., Jaffe, E.S. and Raffeld, M. (1993) "p53 mutation is associated with progression in follicular lymphomas", Blood 82, 1994–2004.
   PubMed Web of Science ®Google Scholar
• Lo Coco, F., Gaidano, G., Louie, D.C., Offit, K., Chaganti, R.S. and Dalla-Favera, R. (1993) "p53 mutations are associated with histologic transformation of follicular lymphoma", Blood 82, 2289–2295.
   PubMed Web of Science ®Google Scholar
• Lossos, IS. and Levy, R. (2000) "Higher-grade transformation of follicle center lymphoma is associated with somatic mutation of the noncoding regulatory region of the BCL- 6 gene", Blood 96, 635–639.
   PubMed Web of Science ®Google Scholar
• Capello, D., Vitolo, U., Pasqualucci, L., Quattrone, S., Migliaretti, G., Fassone, L., Ariatti, C., Vivenza, D., Gloghini, A., Pastore, C., Lanza, C., Nomdedeu, J., Botto, B., Freilone, R., Buonaiuto, D., Zagonel, V, Gallo, E., Palestro, G., Saglio, G., Dalla-Favera, R., Carbone, A. and Gaidano, G. (2000) "Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia", Blood 95, 651–659.
   PubMed Web of Science ®Google Scholar
• Szereday, Z., Csernus, B., Nagy, M., Laszlo, T., Warnke, R.A. and Matolcsy, A. (2000) "Somatic mutation of the 5' noncoding region of the BCL-6 gene is associated with intraclonal diversity and clonal selection in histological transformation of follicular lymphoma", Am. J. PathoL 156, 1017–1024.
   PubMed Web of Science ®Google Scholar
• Matolcsy, A., Casali, P., Warnke, R.A. and Knowles, D.M. (1996) "Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated Bc1-2 gene", Blood 88, 3937–3944.
   PubMed Web of Science ®Google Scholar
• Elenitoba-Johnson, K.S., Gascoyne, RD., Lim, M.S., Chhanabai, M., Jaffe, E.S. and Raffeld, M. (1998) "Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma", Blood 91, 4677–4685.
   PubMed Web of Science ®Google Scholar
• Pinyol, M., Cobo, F., Bea, S., Jares, P., Nayach, I., Fernandez, P.L., Montserrat, E., Cardesa, A. and Campo, E. (1998) "p16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas", Blood 91, 2977–2984.
   PubMed Web of Science ®Google Scholar
• Reimer, T., Herrnring, C., Koczan, D., Richter, D., Gerber, B., Kabelitz, D., Friese, K. and Thiesen, H.J. (2000) "FasL:Fas ratio—a prognostic factor in breast carcinomas", Cancer Res. 60, 822–828.
   PubMed Web of Science ®Google Scholar
• Muschen, M., Moers, C., Warskulat, U., Niederacher, D., Betz, B., Even, J., Lim, A., Josien, R., Beckmann, M.W. and Haussinger, D. (1999) "CD95 ligand expression in dedifferentiated breast cancer", J. Pathol. 189, 378–386.
   PubMed Web of Science ®Google Scholar
• Xiao, W. and Oefner, P.J. (2001) "Denaturing high-performance liquid chromatography: a review", Hum. Mutat. 17, 439–474.
   PubMed Web of Science ®Google Scholar
• Lossos, IS., Alizadeh, A.A., Diehn, M., Warnke, R., Thortstenson, Y, Oefner, P.J., Brown, P.O., Botstein, D. and Levy, R. (2002) "Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alterative patterns with increased or decreased expression of c-myc and its regulated genes", Proc. Nall Acad. Sci. USA 99, 8886–8891.
   PubMed Web of Science ®Google Scholar