CD34 Cell Dose and Chronic Graft-versus-Host Disease after Human Leukocyte Antigen-Matched Sibling Hematopoietic Stem Cell Transplantation

References

• Andrews, R.G., Singer, J.W. and Bernstein, I.D. (1986) "Mono-clonal antibody 12.8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors", Blood, 67, 842–845.
   PubMed Web of Science ®Google Scholar
• Krause, D.S., Fackler, Mi., Civin, CI. and May, W.S. (1996) "CD34: structure, biology, and clinical unity", Blood, 87, 1–13.
   Google Scholar
• Bensinger, W.I., Longin, K., Appelbaum, F., Rowley, S., Weaver, C., Lilleby, K., et al. (1994) "Peripheral blood stem cells (PBSCs) collected after recombinant granulocyte colony stimulating factor (rhG-CSF): an analysis of factors correlating with the tempo of engraftment after transplantation", British Journal of Haematology, 87, 825–831.
   Google Scholar
• Bensinger, W., Appelbaum, F., Rowley, S., Storb, R., Sanders, J., Lilleby, K., et al. (1995) "Factors that influence collection and engraftment of autologous peripheral-blood stem cells", Journal of Clinical Oncology, 13, 2547–2555.
   Google Scholar
• Anasetti, C., Amos, D., Beatty, PG., Appelbaum, FR., Bensinger, W., Buckner, CD., et al. (1989) "Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma", New England Journal of Medicine, 320, 197–204.
   Google Scholar
• Mielcarek, M. and Torok-Storb, B. (1997) "Phenotype and engraftment potential of cytokine-mobilized peripheral blood mononuclear cells", Current Opinion in Hematology, 4, 176— 182.
   Google Scholar
• Martin, P.J., Hansen, JA., Torok-Storb, B., Durnam, D., Przepiorka, D., O'Quigley, J., et al. (1988) "Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow trans-plants", Bone Marrow Transplantation, 3, 445–456.
   PubMed Web of Science ®Google Scholar
• Martin, P.J. (1996) "Prevention of allogeneic marrow graft rejection by donor T cells that do not recognize recipient alloantigens: potential role of a veto mechanism", Blood, 88, 962–969.
   Google Scholar
• Martin, P.J. (1990) "The role of donor lymphoid cells in allo-geneic marrow engraftment", Bone Marrow Transplantation, 6, 283— 289.
   PubMed Web of Science ®Google Scholar
• Storb, R., Epstein, R.B., Bryant, J., Ragde, H. and Thomas, E.D. (1968) "Marrow grafts by combined marrow and leukocyte infusions in unrelated dogs selected by histocompatibility typing", Transplantation, 6, 587–593.
   Google Scholar
• Deeg, Hi., Storb, R., Weiden, P.L., Shulman, H.M., Graham, T.C., Torok-Storb, B.J. and Thomas, E.D. (1979) "Abrogation of resistance to and enhancement of DLA-nonidentical unrelated marrow grafts in lethally irradiated dogs by thoracic duct lymphocytes", Blood, 53, 552–557.
   Google Scholar
• Sullivan, KM., Agura, E., Anasetti, C., Appelbaum, FR., Badger, C., Bearman, S., et al. (1991) "Chronic graft-versus-host disease and other late complications of bone marrow transplantation", Semi-nars in Hematology, 28, 250–259.
   Google Scholar
• Gratwohl, A., Hermans, J., Apperley, J., Arcese, W., Bacigalupo, A., Bandini, G., et al. (1995) "Acute graft-versus-host disease: grade and outcome in patients with chronic myelogenous leukemia", (Review). Blood, 86, 813 — 818.
   PubMed Web of Science ®Google Scholar
• Glucksberg, H., Storb, R., Fefer, A., Buckner, C.D., Neiman, P.E., Clift, R.A., et al. (1974) "Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors", Transplantation, 18, 295–304.
   Google Scholar
• Weisdorf, D., Hakke, R., Blazar, B., Miller, W., McGlave, P., Ramsay, N., et al. (1991) "Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation", Transplantation, 51, 1197 — 1203.
   Google Scholar
• Storb, R., Prentice, R.L., Sullivan, KM., Shulman, H.M., Deeg, Hi., Doney, K.C., et al. (1983) "Predictive factors in chronic graft-versus-host disease in patients with aplastic anemia treated by marrow transplantation from HLA-identical siblings", Annals of Internal Medicine, 98, 461 —466.
   Google Scholar
• Storb, R., Doney, K.C., Thomas, E.D., Appelbaum, F., Buckner, C.D., Clift, R.A., et al. (1982) "Marrow transplantation with or without donor buffy coat cells for 65 transfused aplastic anemia patients", Blood, 59, 236–246.
   PubMed Web of Science ®Google Scholar
• Bensinger, W.I., Martin, P.J., Storer, B., Clift, R., Forman, Si., Negrin, R., et al. (2001) "Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers", New England Journal of Medicine, 344, 175 — 181.
   Google Scholar
• Champlin, R.E., Schmitz, N., Horowitz, MM., Chapuis, B., Chopra, R., Cornelissen, ii., et al. (2000) "Blood stem cells compared with bone marrrow as a source of hematopoietic cells for allogeneic transplantation", Blood, 95, 3702— 3709.
   Google Scholar
• Powles, R., Mehta, J., Kulkarni, S., Treleavan, J., Millar, B., Marsden, J., et al. (2000) "Allogeneic blood and bone-marrow stem-cell transplantation in haematological malignant diseases: a randomised trial", Lancet, 355, 1231–1237.
   PubMed Web of Science ®Google Scholar
• Heldal, D., Tjonnfjord, G.E., Brinch, L., Albrechtsen, D., Egeland, T., Steen, R., et al. (2000) "A randomised study of allogeneic transplantation with stem cells from blood or bone marrow", Bone Marrow Transplantation, 25, 1129 — 1136.
   Google Scholar
• Ringden, O., Remberger, M., Runde, V., Bornhauser, M., Blau, I.W., Basara, N., et al. (1999) "Peripheral blood stem cell transplantation from unrelated donors: a comparison with marrow transplantation", Blood, 94, 455–464.
   Google Scholar
• Blaise, D., Kuentz, M., Fortanier, C., Bourhis, J.H., Milpied, N., Sutton, L., et al. (2000) "Randomized trial of bone marrow versus lenograstim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Societe Française de Greffe de Moelle", Journal of Clinical Oncology, 18, 537— 571.
   Web of Science ®Google Scholar
• Vigorito, AC., Azevedo, W.M., Marques, J.F., Azevedo, A.M., Eid, K.A., Aranha, F.J., et al. (1998) "A randomised, prospective comparison of allogeneic bone marrow and peripheral blood progenitor cell transplantation in the treatment of haematological malignancies", Bone Marrow Transplantation, 22, 1145 — 1151.
   Google Scholar
• Schmitz, N., Beksac, M., Hasenclever, D., Bacigalupo, A., Ruutu, T., Nagler, A., et al. (2000) "A randomised study from the European Group for Blood and Marrow Transplantation comparing allogeneic transplantation of filgrastim-mobilised peripheral blood progenitor cells with bone marrow transplantation in 350 patients (pts) with leukemia", Blood, 96 (Part 1), 481a, #2068 (Abstract).
   Google Scholar
• Shlomchik, W.D., Couzens, M.S., Tang, C.B., McNiff, J., Robert, M.E., Liu, J., et al. (1999) ‘‘Prevention of graft versus host disease by inactivation of host antigen-presenting cells’’, Science, 285, 412 –415.
   Google Scholar
• Atkinson, K., Incefy, G.S., Storb, R., Sullivan, K.M., Iwata, T., Dardenne, M., et al. (1982) ‘‘Low serum thymic hormone levels in patients with chronic graft-versus-host disease’’, Blood, 59, 1073 –1077.
   Google Scholar
• Beschorner, W.E., Tutschka, P.J. and Santos, G.W. (1982) "Chronic graft-versus-host disease in the rat radiation chimera: I. Clinical features, hematology, histology, and immunopathology in long-term chimeras", Transplantation, 33, 393–399.
   Google Scholar
• Tutschka, P.J., Teasdall, R., Beschorner, W.E. and Santos, G.W. (1982) ‘‘Chronic graft-versus-host disease in the rat radiation chimera. II. Immunological evaluation in long-term chimeras’’, Transplantation, 34, 289 – 294.
   Google Scholar
• Storek, J., Gooley, T., Siadak, M., Bensinger, W.I., Maloney, D.G., Chauncey, T.R., et al. (1997) ‘‘Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graftversus- host disease’’, Blood, 90, 4705 – 4709.
   Google Scholar
• Majolino, I., Saglio, G., Scime, R., Serra, A., Cavallaro, A.M., Fiandaca, T., et al. (1996) ‘‘High incidence of chronic GVHD after primary allogeneic peripheral blood stem cell transplantation in patients with hematologic malignancies’’, Bone Marrow Transplantation, 17, 555 – 560.
   Google Scholar
• Scott, M.A., Gandhi, M.K., Jestice, H.K., Mahendra, P., Bass, G. and Marcus, R.E. (1998) "A trend towards an increased incidence of chronic graft-versus-host disease following allogeneic peripheral blood progenitor cell transplantation: a case controlled study",
   Google Scholar
• Levine, J.E., Wiley, J., Kletzel, M., Yanik, G., Hutchinson, R.J., Koehler, M., et al. (2000) "Cytokine-mobilized allogeneic peripheral blood stem cell transplants in children result in rapid engraftment and a high incidence of chronic GVHD", Bone Marrow Transplan-tation, 25, 13 — 18.
   Google Scholar
• Kalayoglu-Besisik, S., Budak-Alpdogan, T., Nuri, Y.M., Sargin, D. and Tangun, Y. (1998) ‘‘High risk of chronic graft-versus-host disease in unmanipulated allogeneic peripheral blood stem cell transplantation’’, Blood, 92, 2973 – 2975.
   Google Scholar
• Solano, C., Martinez, C., Brunet, S., Tomas, J.F., Urbano, LA., Zuazu, J., et al. (1998) "Chronic graft-versus-host disease after
   Google Scholar
• Schmitz, N., Beksac, M., Hasenclever, D., Bacigalupo, A., Ruutu, T., Nagler, A., et al. (2002) "Transplantation of mobilized
   Google Scholar
• Millin, G., Russell, N.H., Hutchinson, R.M., Morgan, G., Potter, M., Pagliuca, A., et al. (1997) "Allogeneic peripheral blood stem cell transplantation for haematological malignancies—an analysis of
   Google Scholar
• Cutler, C., Gin, S., Jeyapalan, S., Paniagua, D., Viswanathan, A. and Antin, J.H. (2001) "Acute and chronic graft-versus-host disease after allogeneic peripheral-blood stem-cell and bone marrow
   Google Scholar
• Niederwieser, D., Pepe, M., Storb, R., Witherspoon, R., Longton, G. and Sullivan, K. (1989) "Factors predicting chronic graft-versus-host disease and survival after marrow transplantation for aplastic
   Google Scholar
• Atkinson, K., Horowitz, MM., Gale, R.P., van Bekkum, D.W., Gluckman, E., Good, R.A., et al. (1990) "Risk factors for chronic graft-versus-host disease after HLA-identical sibling bone marrow transplantation", Blood, 75, 2459–2464.
   Google Scholar
• Ochs, L.A., Miller, W.J., Filipovich, A.H., Haake, R.J., McGlave,
   Google Scholar
• Pan, L., Delmonte, J. Jr., Jalonen, C.K. and Ferrara, J.L.M. (1995) "Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft versus host disease", Blood, 86, 4422–4429.
   PubMed Web of Science ®Google Scholar
• Sloand, E.M., Kim, S., Maciejewski, J.P., van Rhee, F., Chaudhuri, A., Barrett, J., et al. (2000) "Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lympho-cytes in vitro and in vivo", Blood, 95, 2269 — 2274.
   Google Scholar
• Arpinati, M., Green, CL., Heimfeld, S., Heuser, J.E. and Anasetti, C. (2000) "Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells", Blood, 95, 2484 — 2490.
   Google Scholar
• Tanaka, J., Imamura, M., Kasai, M., Hashino, S., Kobayashi, S., Noto, S., et al. (1996) "Th2 cytokines (IL-4, IL-10 and IL-13) and IL-12 mRNA expression by concanavalin A-stimulated peripheral blood mononuclear cells during chronic graft-versus-host disease", European Journal of Haematology, 57, 1 1 1 —113.
   Google Scholar
• Okubo, T., Hagiwara, E., Ohno, S., Tsuji, T., Ihata, A., Ueda, A., et al. (1999) "Administration of an IL-12-encoding DNA plasmid prevents the development of chronic graft-versus-host disease (GVHD)", Journal of Immunology, 162, 4013 — 4017.
   Google Scholar
• Mielcarek, M., Martin, P. and Torok-Storb, B. (1997) "Suppression of alloantigen-induced T-cell proliferation by CD14 + cells derived from granulocyte colony-stimulating factor (G-CSF)-mobilized peripheral blood mononuclear cells", Blood, 89, 1629 — 1634.
   Google Scholar
• Mielcarek, M., Graf, L., Johnson, G. and Torok-Storb, B. (1998) "Production of interleukin-10 by granulocyte colony-stimulating factor-mobilized blood products: a mechanism for monocyte-mediated suppression of T cell proliferation", Blood, 92, 215— 222.
   Google Scholar
• Weaver, C.H., Hazelton, B., Birch, R., Palmer, P., Allen, C., Schwartzberg, L., et al. (1995) "An analysis of engraftment kinetics as a function of the CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy", Blood, 86, 3961–3969.
   PubMed Web of Science ®Google Scholar
• Nakamura, R., Bahceci, E., Read, E.J., Leitman, S.F., Carter, CS., Childs, R., et al. (2001) "Transplant dose of CD34( +) and CD3( +) cells predicts outcome in patients with haematological malignancies undergoing T cell-depleted peripheral blood stem cell transplants with delayed donor lymphocyte add-back", British Journal of Haematology, 115, 95 — 104.
   Google Scholar
• Singhal, S., Powles, R., Treleaven, J., Kulkarni, S., Sirohi, B., Horton, C., et al. (2000) "A low CD34 + cell dose results in higher mortality and poorer survival after blood or marrow stem cell transplantation from HLA-identical siblings: should 2 x 10(6) CD34 + cells/kg be considered the minimum threshold?", Bone Marrow Transplantation, 26, 489–496.
   PubMed Web of Science ®Google Scholar
• Mavroudis, D., Read, E., Cottler-Fox, M., Couriel, D., Molldrem, J., Carter, C., et al. (1996) "CD34 + cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies", Blood, 88, 3223 — 3229.
   Google Scholar
• Bahceci, E., Read, E.J., Leitman, S., Childs, R., Dunbar, C., Young, N.S., et al. (2000) "CD34 + cell dose predicts relapse and survival after T-cell depleted HLA-identical haematopoietic stem cell transplantation (HSCT) for haematological malignancies", British Journal of Haematology, 108, 408 —414 (Abstract).
   Google Scholar
• Bittencourt, H., Rocha, V., Chevret, S., Socie, G., Esperou, H., Devergie, A., et al. (2002) "Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation", Blood, 99, 2726–2733.
   PubMed Web of Science ®Google Scholar
• Rocha, V., Labopin, M., Gluckman, E., Powles, R., Arcese, W., Bacigalupo, A., et al. (2002) "Relevance of bone marrow cell dose on allogeneic transplantation outcomes for patients with acute myeloid leukemia in first complete remission: results of a European survey", Journal of Clinical Oncology, 20, 4324–4330.
   PubMed Web of Science ®Google Scholar
• Zaucha, J.M., Gooley, T., Bensinger, W.I., Heimfeld, S., Chauncey, T.R., Zaucha, R., et al. (2001) "CD34 cell dose in granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cell grafts affects engraftment kinetics and development of extensive chronic graft-versus-host disease after human leukocyte antigen-identical sibling transplantation", Blood, 98, 3221–3227.
   PubMed Web of Science ®Google Scholar
• Przepiorka, D., Anderlini, P., Saliba, R., Cleary, K., Mehra, R., Khouri, I., et al. (2001) "Chronic graft-versus-host disease after allogeneic blood stem cell transplantation", Blood, 98, 1695 — 1700.
   Web of Science ®Google Scholar
• Menendez, P., Perez-Simon, JA., Mateos, MV., Caballero, M.D., Gonzalez, M., San-Miguel, J.F., et al. (2002) "Influence of the different CD34 + and CD34- cell subsets infused on clinical outcome after non-myeloablative allogeneic peripheral blood transplantation from human leucocyte antigen-identical sibling donors", British Journal of Haematology, 119, 135— 143.
   Google Scholar
• Handgretinger, R., Lang, P., Klingebiel, T. and Niethammer, D. (2002) "CD34 stem cell dose and development of extensive chronic graft-versus-host disease", Blood, 99, 3875–3876.
   PubMed Web of Science ®Google Scholar
• Rocha, V., Carmagnat, MV., Chevret, S., Flinois, O., Bittencourt, H., Esperou, H., et al. (2001) "Influence of bone marrow graft lymphocyte subsets on outcome after HLA-identical sibling transplants", Experimental Hematology, 29, 1347 — 1352.
   Google Scholar
• Morariu-Zamfir, R., Rocha, V., Devergie, A., Socie, G., Ribaud, P., Esperou, H., et al. (2001) "Influence of CD34( + ) marrow cell dose on outcome of HLA-identical sibling allogeneic bone marrow transplants in patients with chronic myeloid leukaemia", Bone Marrow Transplantation, 27, 575–580.
   PubMed Web of Science ®Google Scholar
• Ryncarz, R.E. and Anasetti, C. (1998) "Expression of CD86 on human marrow CD34 ± cells identifies immunocompetent com-mitted precursors of macrophages and dendritic cells", Blood, 91, 3892— 3900.
   Google Scholar
• Rondelli, D., Andrews, R.G., Hansen, JA., Ryncarz, R., Faerber, M.A. and Anasetti, C. (1996) "Alloantigen presenting function of normal human CD34 + hematopoietic cells", Blood, 88, 2619 — 2625.
   Google Scholar
• Couban, S., Simpson, DR., Barnett, Mi., Bredeson, C., Hubesch, L., Howson-Jan, K., et al. (2002) "A randomized multicenter comparison of bone marrow and peripheral blood in recipients of matched sibling allogeneic transplants for myeloid malignancies", Blood, 100, 1525–1531.
   PubMed Web of Science ®Google Scholar
• Brown, R.A., Adkins, D., Goodnough, L.T., Haug, JS., Todd, G., Wehde, M., et al. (1997) "Factors that influence the collection and engraftment of allogeneic peripheral-blood stem cells in patients with hematologic malignancies", Journal of Clinical Oncology, 15, 3067–3074.
   Google Scholar
• Urbano-Ispizua, A., Carreras, E., Mann, P., Rovira, M., Martinez, C., Fernandez-Aviles, F., et al. (2001) "Allogeneic transplantation of CD34( +) selected cells from peripheral blood from human leukocyte antigen-identical siblings: detrimental effect of a high number of donor CD34( + ) cells?", Blood, 98, 2352–2357.
   Google Scholar
• Urbano-Ispizua, A., Brunet, S., Solano, C., Moraleda, J.M., Rovira, M., Zuazu, J., et al. (2001) "Allogeneic transplantation of CD34 + -selected cells from peripheral blood in patients with myeloid malignancies in early phase: a case control comparison with unmodified peripheral blood transplantation", Bone Marrow Transplantation, 28, 349–354.
   PubMed Web of Science ®Google Scholar