Derivative Chromosome 9 Deletions in Chronic Myeloid Leukemia are Associated with Loss of Tumor Suppressor Genes

References

• Shtivelman, E., Lifshitz, B., Gale, R.P. and Canaani, E. (1985) "Fused transcript of abl and bcr genes in chronic myelogenous leukaemia", Nature, 315, 550— 554.
   Google Scholar
• Sinclair, P.B., Nacheva, E.P., Leversha, M., Telford, N., Chang, J., Reid, A., et al. (2000) "Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia", Blood, 95, 738–743.
   PubMed Web of Science ®Google Scholar
• Huntly, B.J., Reid, AG., Bench, A.J., Campbell, Li., Telford, N., Shepherd, P., et al. (2001) "Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia", Blood, 98, 1732— 1738.
   Web of Science ®Google Scholar
• Kolomietz, E., Al-Maghrabi, J., Brennan, S., Karaskova, J., Minkin, S., Lipton, J., et al. (2001) "Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis", Blood, 97, 3581 — 3588.
   Google Scholar
• Cohen, N., Rozenfeld-Granot, G., Hardan, I., Brok-Simoni, F., Amariglio, N., Rechavi, G., et al. (2001) "Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene. Expression profiling, resistance to interferon therapy, and poor prognosis" Cancer Genetics and Cytogenetics, 128, 114 — 119.
   Google Scholar
• de la Fuente, J., Merx, K., Steer, E.J., Muller, M., Szydlo, R.M., Maywald, O., et al. (2001) "ABL-BCR expression does not correlate with deletions on the derivative chromosome 9 or survival in chronic myeloid leukemia", Blood, 98, 2879 — 2880.
   Google Scholar
• Loncarevic, IF., Romer, J., Starke, H., Heller, A., Bleck, C., Ziegler, M., et al. (2002) "Heterogenic molecular basis for loss of ABL1-BCR transcription: deletions in der(9)t(9;22) and variants of standard t(9;22) in BCR-ABL1-positive chronic myeloid leukemia", Genes, Chromosomes and Cancer, 34, 193–200.
   Google Scholar
• Huntly, B.J., Bench, A.J., Delabesse, E., Reid, AG., Li, J., Scott, MA., et al. (2002) "Derivative chromosome 9 deletions in chronic myeloid leukemia: poor prognosis is not associated with loss of ABL-BCR expression, elevated BCR-ABL levels, or karyotypic instability", Blood, 99, 4547–4553.
   Google Scholar
• Storlazzi, CT., Specchia, G., Anelli, L., Albano, F., Pastore, D., Zagaria, A., et al. (2002) "Breakpoint Characterization of der(9) deletions in CML patients", Genes, Chromosomes and Cancer, 35, 271— 276.
   Google Scholar
• Cook, W.D. and McCaw, B.J. (2000) "Accommodating haploin-sufficient tumor suppressor genes in Knudson's model", Oncogene, 19, 3434— 3438.
   Google Scholar
• van Dongen, J.J., Macintyre, E.A., Gabert, J.A., Delabesse, E., Rossi, V., Saglio, G., et al. (1999) "Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia", Leukemia, 13, 1901 — 1928.
   Google Scholar
• The Italian Cooperative Study Group on chronic myeloid leukemia. (1994) "Interferon alfa-2a as compared with conventional che-motherapy for the treatment of chronic myeloid leukemia", New England Journal of Medicine, 330, 820–825.
   PubMed Web of Science ®Google Scholar
• Mitelman, F. (1995) ISCN. An International System for Human Cytogenetic Nomenclature, ed. Basel: Karger.
   Google Scholar
• Lichter, P., Tang Chang, CJ., Call, K., Hermanson, G., Evans, G.A., Housman, D., et al. (1990) "High resolution mapping of human chromosomes 11 by in situ hybridization with cosmid clones", Science, 247, 64–69.
   PubMed Web of Science ®Google Scholar
• Albano, F., Specchia, G., Anelli, L., Zagaria, A., Storlazzi, C.T., Buquicchio, C., et al. (2003) "Genomic deletions on other chromosomes involved in variant t(9;22) chronic myeloid leukemia cases", Genes, Chromosomes and Cancer, 36, 353–360.
   PubMed Web of Science ®Google Scholar
• Quon, K.C. and Berns A. (2001) "Haplo-insufficiency? Let me count the ways", Gene Development, 15, 2917 — 2921.
   Google Scholar
• Venkatachalam, S., Shi, Y.P., Jones, S.N., Vogel, H., Bradley, A., Pinkel, D., et al. (1998) "Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation", EMBO Journal, 17, 4657–4667.
   Google Scholar
• Fero, ML., Randel, E., Gurley, K.E., Roberts, J.M. and Kemp, C.J. (1998) "The murine gene p27Kip 1 is haplo-insufficient for tumour suppression", Nature, 396, 177 — 180.
   Google Scholar
• Cho, KR., Oliner, JD., Simons, J.W., Hedrick, L., Fearon, E.R., Preisinger, AC., et al. (1994) "The DCC gene: structural analysis and mutations in colorectal carcinomas", Genomics, 19, 525 — 531.
   Google Scholar
• Kinzler, K.W. and Vogelstein, B. (1997) "Cancer-susceptibility genes. Gatekeepers and caretakers", Nature, 386, 761–763.
   PubMed Web of Science ®Google Scholar
• Versteege, I., Sevenet, N., Lange, J., Rousseau Merck, M.F., Ambros, P., Handgretinger, R., et al. (1998) "Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer", Nature, 394, 203 — 206.
   Google Scholar
• Biegel, J.A., Zhou, J.Y., Rorke, L.B., Stenstrom, C., Wainwright, L.M., and Flogelgren, B. (1999) "Germ-line and acquired mutations of INI1 a atypical teratoid and rhabdoid tumours", Cancer Research, 59, 74–79.
   PubMed Web of Science ®Google Scholar
• Biegel, J.A., Fogelgren, B., Zhou, J.Y., James, CD., Janss, A.J., Allen, J.C., et al. (2000) "Mutations of the INI1 rhabdoid tumor suppressor gene in medulloblastomas and primitive neuroectoder-mal tumors of the central nervous system", Clinical Cancer Research, 6, 2759 — 2763.
   Google Scholar
• DeCristofaro, M.F., Betz, B.L., Wang, W. and Weissman, B.E. (1999) "Alteration of SNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors", Oneogene, 18, 7559–7565.
   Google Scholar
• Grand, F., Kulkarni, S., Chase, A., Goldman, J.M., Gordon, M. and Cross, N.C.P. (1999) "Frequent deletion of hSNF5IINI1, a component of the SWI/SNF complex, in chronic myeloid leuke-mia", Cancer Research, 59, 3780— 3784.
   Google Scholar
• Salinas, A.E. and Wong, M.G. (1999) "Glutathione S-trans-ferases—a review", Current Medical Chemistry, 6, 279–309.
   PubMed Web of Science ®Google Scholar
• Voso, M.T., D'Alo', F., Putzulu, R., Mele, L., Scardocci, A., Chiusolo, P., et al. (2002) "Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia", Blood, 100, 2703–2707.
   PubMed Web of Science ®Google Scholar
• Rebbeck, T.R. (1997) "Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility", Cancer Epidemiology Biomarkers Prevention, 6, 733— 743.
   Google Scholar
• Polyak, K., Xia, Y., Zweier, J.L., Kinzler, K.W. and Vogelstein, B. (1997) "A model for p53-induced apoptosis", Nature, 18, 237–238.
   Google Scholar
• Kantarjian, H.M., Cortes, J.E., O'Brien, S., Giles, F., Garcia-Manero, G., Faderl, S., et al. (2003) "Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome—positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses", Blood, 101, 97–100.
   PubMed Web of Science ®Google Scholar