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Original Article

In Multiple Myeloma Clonotypic CD38 − /CD19 + /CD27 +  Memory B Cells Recirculate Through Bone Marrow, Peripheral Blood and Lymph Nodes

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Pages 1413-1417 | Received 22 Nov 2003, Published online: 03 Aug 2009

Reference

  • Billadeau, D., Ahmann, G., Greipp, P. and Van, Ness B. (1993) "The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell", J. Exp. Med., 178, 1023–1031.
  • Corradini, P., Boccadoro, M., Voena, C. and Pileri, A. (1993) "Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to C mu sequence in immunoglobulin (IgG)- and IgA-secreting multiple myelomas", J. Exp. Med., 178(3), 1091–1096.
  • Rasmussen, T., Jensen, L. and Johnsen, H.E. (2001) "The Clonal Hierachy in Multiple Myeloma", Acta Oncologica, 39(7), 765–770.
  • Agematsu, K., Holcibara, S., Nagumo, H. and Komiyama, A. (2000) "CD27: a memory B-cell marker", Immunol. Today, 21(5), 204 — 206.
  • Tang, ML., Steeber, D.A., Zhang, X.Q. and Tedder, T.F. (1998) "Intrinsic differences in L-selectin expression levels affect T and B lymphocyte subset-specific recirculation pathways", J. Immunol., 160(10), 5113–5121.
  • Forster, R., Mattis, A.E., Kremmer, E., Wolf, E., Brem, G. and Lipp, MA. (1996) "Putative chemolcine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen", Cell, 87(6), 1037–1047.
  • Gunn, M.D., Ngo, V.N., Ansel, KM., Ekland, E.H., Cyster, J.G. and Williams, L.T. (1998) "A B-cell-homing chemolcine made in lymphoid follicles activates Burlcitt's lymphoma receptor-1", Nature, 391(6669), 799–803.
  • Legler, D.F., Loetscher, M., Roos, R.S., Clark-Lewis, I., Baggiolini, M. and Moser, B. (1998) "B cell-attracting chemolcine 1, a human CXC chemolcine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5", J. Exp. Med., 187(4), 655–660.
  • Forster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Muller, I., Wolf, E., et al. (1999) "CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs", Cell, 99(1), 23 — 33.
  • Gunn, M.D., Kyuwa, S., Tam, C., Kalciuchi, T., Matsuzawa, A., Williams, L.T., et al. (1999) "Mice lacking expression of secondary lymphoid organ chemolcine have defects in lymphocyte homing and dendritic cell localization", J. Exp. Med., 189(3), 451–460.
  • Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S., Kitamura, Y., et al. (1996) "Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemolcine PBSF/SDF-1", Nature, 382(6592), 635–638.
  • Krzysiek, R., Lefevre, E.A., Bernard, J., Foussat, A., Galanaud, P., Louache, F., et al. (2000) "Regulation of CCR6 chemolcine receptor expression and responsiveness to macrophage inflammatory pro-tein-3alpha/CCL20 in human B cells", Blood, 96(7), 2338 — 2345.
  • Rasmussen, T., Jensen, L., Honore, L., Andersen, H. and Johnsen, H.E. (1999) "Circulating clonal cells in multiple myeloma do not express CD34 MRNA, as measured by single-cell and real-time RT-PCR assays", Br. J. Haematol., 107, 818 —824.
  • Rasmussen, T., Jensen, L., Honore, L. and Johnsen, H.E. (2000) "Frequency and kinetics of polyclonal and clonal B-cells in the peripheral blood of patients being treated for multiple myeloma", Blood, 96(13), 4357–4359.
  • Vescio, R.A., Cao, J., Hong, C.H., Lee, J.C., Wu, C.H., Der, Danielian, M., et al. (1995) "Myeloma Ig heavy chain V region sequences reveal prior antigenic selection and marked somatic mutation but no intraclonal diversity", J. Immunol., 155(5), 2487 — 2497.
  • Bakkus, M.H., Heirman, C., Van Riet, I., Van Camp, B. and Thielemans, K. (1992) "Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation", Blood, 80(9), 2326–2335.
  • Gray, D. (1993) "Immunological memory", Ann. Rev. Immunol., 11, 49–77.
  • Kraal, G., Weissman, I.L. and Butcher, E.C. (1988) "Memory B cells express a phenotype consistent with migratory competence after secondary but not short-term primary immunization", Cell Immunol., 115(1), 78–87.
  • Young, A.J., Marston, W.L., Dessing, M., Dudler, L. and Hein, W.R. (1997) "Distinct recirculating and non-recirculating B-lymphocyte pools in the peripheral blood are defined by coordinated expression of CD21 and L-selectin", Blood, 90(12), 4865–4875.
  • Bleul, C.C., Schultze, J.L. and Springer, TA. (1998) "B lymphocyte chemotaxis regulated in association with microanatomic localiza-tion, differentiation state, and B cell receptor engagement", J. Exp. Med., 187(5), 753 — 762.
  • Hargreaves, D.C., Hyman, P.L., Lu, T.T., Ngo, V.N., Bidgol, A., Suzuki, G., et al. (2001) "A coordinated change in chemolcine responsiveness guides plasma cell movements", J. Exp. Med., 194(1), 45–56.
  • Iwasaki, A. and Kelsall, B.L. (2000) "Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemolcines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemolcine", J. Exp. Med., 191(8), 1381–1394.
  • Cook, D.N., Prosser, D.M., Forster, R., Zhang, J., Kuklin, NA., Abbondanzo, S.J., et al. (2000) "CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue", Immunity, 12(5), 495–503.
  • Varona, R., Villares, R., Carramolino, L., Goya, I., Zaballos, A., Gutierrez, J., et al. (2001) "CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses", J. Clin. Invest., 107(6), R37 — R45.
  • Liu, Y.J., Barthelemy, C., de Bouteiller, 0., Arpin, C., Durand, I. and Banchereau, J. (1995) "Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2", Immunity, 2(3), 239 — 248.

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