71
Views
13
CrossRef citations to date
0
Altmetric
Original Article

B-cell Chronic Lymphocytic Leukemia with Aberrant CD8 Expression: Genetic and Immunophenotypic Analysis of Prognostic Factors

, , , , , & show all
Pages 1677-1681 | Received 27 Feb 2004, Published online: 26 Aug 2009

References

  • Mfiller-Hermelink, H.K., Catovsky, D., Montserrat, E. and Heimpel, H. (2001) Chronic lymphocytic leukemia/small lympho-cytic leukemia. In Pathology and Genetics of Tumours of Haema-tomoietic and Lymphoid Tissues, edited by E.S. Jaffe, N.L. Harris, H. Stein and J.W. Vardiman. Lyon: IARC Press.
  • Kurec, AS., Threatte, G.A., Gottlieb, A.J., Smith, J.R., Anderson, J. and Davey, F.R. (1992) "Immunophenotypic Subclassification of Chronic Lymphocytic-Leukemia (C11)", British Journal of Haema-tology, 81, 45–51.
  • Kaleem, Z., White, G. and Zutter, M.M. (2001) "Aberrant expression of T-cell-associated antigens on B-cell non-Hodgkin lymphomas", Am. J. Clin. Pathol., 115, 396–403.
  • Greaves, M.F., Chan, L.C., Furley, A.J.W., Watt, S.M. and Molgaard, H.V. (1986) "Lineage Promiscuity in Hematopoietic Differentiation and Leukemia", Blood, 67, 1–11.
  • Attadia, V., Alosi, M., Improta, S., Baccarani, M. and De Paoli, P. (1996) "Immunophenotypic and molecular genetic characterization of a case of CD8 + B cell chronic lymphocytic leukemia", Leukemia, 10, 1544 — 1550.
  • Bayo Hanza, M.C., Palacios, M.F., Dourisboure, R., et al. (1999) "CD8 expression in a case of chronic lymphocytic leukemia with trisomy 12", Acta HaematoL, 102, 190— 195.
  • Brunet, C., Bardin, N, Oukhouya, 0. et al. (1998) "A case report: CD8 expression in B-cell chronic lymphocytic leukemia (B-CLL). Prognostic significance of the aberrant CD8 expression", HematoL Cell Ther., 40, 279 — 282.
  • Espinosa, A., Bjork, P., Magnussen, K., Moen, T. and Sorum, Y. (2003) "Aberrant expression of the CD8 antigen in B cell chronic lymphocytic leukaemia", Leuk. Lymphoma, 44, 193–196.
  • Ghosh, K., Sivakumaran, M. and Wood, J.K. (1993) "Aberrant CD8 antigen expression in a patient with B chronic lymphocytic leukaemia showing unusual disease progression", Br. J. HaematoL, 85, 205–206.
  • Islam, A., Vladutiu, A.O., Donahue, T., Akhter, S., Sands, A.M. and Ambrus, J.L. (2000) "CD8 expression on B cells in chronic lymphocytic leukemia: a case report and review of the literature", Arch. PathoL Lab Med., 124, 1361 — 1363.
  • Koelliker, D.D., Steele, P.E., Hurtubise, P.E., Flessa, H.C., Sheng, Y.P. and Swerdlow, S.H. (1994) "CD8-positive B-cell chronic lymphocytic leukemia. A report of two cases", Am. J. Clin. PathoL, 102, 212–216.
  • Mulligan, S.P., Dao, L.P., Francis, SE., et al. (1998) "B-cell chronic lymphocytic leukaemia with CD8 expression: report of 10 cases and immunochemical analysis of the CD8 antigen", British Journal of Haematology, 103, 157 — 162.
  • Crespo, M., Bosch, F., Villamor, N., et al. (2003) "ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia", N. Engl. J. Med., 348, 1764 — 1775.
  • Dung, J., Nuckel, H., Cremer, M., et al. (2003) "ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia", Leukemia, 17, 2426–2434.
  • Haase, D., Feuring-Buske, M., Konemann, S., et al. (1995) "Evidence for malignant transformation in acute myeloid leukemia at the level of early hematopoietic stem cells by cytogenetic analysis of CD34 + subpopulations", Blood, 86, 2906— 2912.
  • Linke, B., Bolz, I., Fayyazi, A., et al. (1997) "Automated high resolution PCR fragment analysis for identification of clonally rearranged immunoglobulin heavy chain genes", Leukemia, 11, 1055— 1062.
  • Van Krieken, J.H., Langerak, A.W., San Miguel, J.F., et al. (2003) "Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936", Hum. PathoL, 34, 359— 361.
  • Parnes, J.R. (1989) "Molecular biology and function of CD4 and CD8", Adv. Immunol., 44, 265–311.
  • Davis, Si., Ikemizu, S., Evans, E.J., Fugger, L., Bakker, T.R. and van der Merwe, P.A. (2003) "The nature of molecular recognition by T cells", Nat. Immunol., 4, 217–224.
  • Dung, J., Naschar, M., Schmucker, U., et al. (2002) "CD38 expression is an important prognostic marker in chronic lympho-cytic leukaemia", Leukemia, 16, 30— 35.
  • Krober, A., Seiler, T., Benner, A., et al. (2002) "V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia", Blood, 100, 1410–1416.
  • Stilgenbauer, S., Bullinger, L., Lichter, P. and Dohner, H. (2002) "Genetics of chronic lymphocytic leukemia: genomic aberrations and V(H) gene mutation status in pathogenesis and clinical course", Leukemia, 16, 993 — 1007.
  • Dohner, H., Stilgenbauer, S., Benner, A., et al. (2000) "Genomic aberrations and survival in chronic lymphocytic leukemia", N. Engl. J. Med., 343, 1910 — 1916.
  • Wiestner, A., Rosenwald, A., Barry, T.S., et al. (2003) "ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile", Blood, 101, 4944–4951.
  • Latour, S. and Veillette, A. (2001) "Proximal protein tyrosine lcinases in immunoreceptor signaling", Curr. Opin. Immunol., 13, 299–306.
  • Elder, M.E. (1998) "ZAP-70 and defects of T-cell receptor signaling", Semin. Hematol., 35, 310— 320.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.