709
Views
60
CrossRef citations to date
0
Altmetric
Original

Significance of macrophage inflammatory protein-1 alpha (MIP-1α) in multiple myeloma

, , &
Pages 1699-1707 | Received 10 May 2005, Published online: 01 Jul 2009

References

  • Menten P, Wuyts A, Van Damme J. Macrophage inflammatory protein-1. Cytokine Growth Factor Reviews 2002; 13: 455–481
  • Lee S C, Brummet M E, Shahabuddin S, Woodworth T G, Georas S N, Leiferman K M, et al. Cutaneous injection of human subjects with macrophage inflammatory protein-1α induces significant recruitment of neutrophils and monocytes. Journal of Immunology 2000; 164: 3392–3401
  • Di Pietro L A, Burdick M, Low Q E, Kunkel S L, Strieter R M. MIP-1α as a critical macrophage chemoattractant in murine wound repair. Journal of Clinical Investigations 1998; 101: 1693–1698
  • Broxmeyer H E, Kim C H. Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities. Experimental Hematology 1999; 27: 1113–1123
  • Watanabe T, Kukita T, Kukita A, Wada N, Toh K, Nagata K, et al. Direct stimulation of osteoclastogenesis by MIP-1alpha: evidence obtained from studies using RAW264 cell clone highly responsive to RANKL. Journal of Endocrinology 2004; 180: 193–201
  • Kukita T, Nomiyama H, Ohmoto Y, Kukita A, Shuto T, Hotokebuchi T, et al. Macrophage inflammatory protein-1 alpha (LD78) expressed in human bone marrow: its role in regulation of hematopoiesis and osteoclast recruitment. Laboratory Investigations 1997; 76: 399–406
  • Han J H, Choi S J, Kurihara N, Koide M, Oba Y, Roodman G D. Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood 2001; 97: 3349–3353
  • Choi S J, Cruz J C, Craig F, Chung H, Devlin R D, Roodman G D, Alsina M. Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma. Blood 2000; 96: 671–675
  • Uneda S, Hata H, Matsuno F, Harada N, Mitsuya Y, Kawano F, Mitsuya H. Macrophage inflammatory protein-1 alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM. British Journal of Haematology 2003; 120: 53–55
  • Politou M, Terpos E, Anagnostopoulos A, Szydlo R, Laffan M, Layton M, et al. Role of receptor activator of nuclear factor-kappa B ligand (RANKL), osteoprotegerin and macrophage protein 1-alpha (MIP-1α) in monoclonal gammopathy of undetermined significance (MGUS). British Journal of Haematology 2004; 126: 686–689
  • Roodman G D, Choi S J. MIP-1 alpha and myeloma bone disease. Cancer Treatment Research 2004; 118: 83–100
  • Blum S, Forsdyke R E, Forsdyke D R. Three human homologs of a murine gene encoding an inhibitor of stem cell proliferation. DNA Cell Biology 1990; 9: 589–602
  • Hirashima M, Ono T, Nakao M, Nishi H, Kimura A, Nomiyama H, et al. Nucleotide sequence of the third cytokine LD78 gene and mapping of all three LD78 gene loci to human chromosome 17. DNA Sequence 1992; 3: 203–212
  • Menten P, Struyf S, Schutyser E, Wuyts A, De Clercq E, Schols D. The LD78 beta isoform of MIP-1 alpha is the most potent CCR5 agonist and HIV-1 inhibiting chemokine. Journal of Clinical Investigations 1999; 104: R1–R5
  • Min D J, Cho M L, Lee S H, Min S Y, Kim W U, Min J K, et al. Augmented production of chemokines by the interaction of type II collagen-reactive T cells with rheumatoid synovial fibroblasts. Arthritis & Rheumatism 2004; 50: 1146–1155
  • Kusugami K, Ando T, Imada A, Ina K, Ohsuga M, Shimizu T, et al. Mucosal macrophage inflammatory protein-1alpha activity in Helicobacter pylori infection. Journal of Gastroenterology & Hepatology 1999; 14: 20–26
  • Schuyler M, Gott K, French V. The role of MIP-1alpha inexperimental hypersensitivity pneumonitis. Lung 2004; 182: 135–149
  • Fuke S, Betsuyaku T, Nasuhara Y, Morikawa T, Katoh H, Nishimura M. Chemokines in bronchiolar epithelium in the development of chronic obstructive pulmonary disease. American Journal of Respiratory Cell Molecular Biology 2004; 31: 405–412
  • Zhao L, Moos M P, Grabner R, Pedrono F, Fan J, Kaiser B, et al. The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia- dependent aortic aneurysm. Natural Medicine 2004; 10: 966–973
  • Cook D N, Beck M A, Coffman T M, Kirby S L, Sheridan J F, Pragnell I B, Smithies O. Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science 1995; 269: 1583–1585
  • Cocchi F, DeVico A L, Yarchoan R, Redfield R, Cleghorn F, Blattner W A, et al. Higher macrophage inflammatory protein (MIP)-1alpha and MIP-1beta levels from CD8 + T cells are associated with asymptomatic HIV-1 infection. Proceedings of the National Academy of Sciences (USA) 2000; 97: 13812–13817
  • Owen-Lynch P J, Czaplewski L G, Hunter M G, Whetton A D. The growth inhibitory role and potential clinical value of macrophage inflammatory protein 1 alpha in myeloid leukemias. Leukemia & Lymphoma 1998; 30: 41–53
  • Kukita T, Nakao J, Hamada F, Kukita A, Inai T, Kurisu K, Nomiyama H. Recombinant LD78 protein, a member of the small cytokine family, enhances osteoclast differentiation in rat bone marrow culture system. Bone Minerals 1992; 19: 215–223
  • Scheven B A, Milne J S, Hunter I, Robins S P. Macrophage-inflammatory protein-1alpha regulates preosteoclast differentiation in vitro. Biochemistry & Biophysics Research Communications 1999; 254: 773–778
  • Lean J M, Murphy C, Fuller K, Chambers T J. CCL9/MIP-1gamma and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts. Journal of Cellular Biochemistry 2002; 87: 386–393
  • Hanyuda M, Kasama T, Isozaki T, Matsunawa M M, Yajima N, Miyaoka H, et al. Activated leucocytes express and secrete macrophage inflammatory protein-1alpha upon interaction with synovial fibroblasts of rheumatoid arthritis via a beta2-integrin/ICAM-1 mechanism. Rheumatology 2003; 42: 1390–1397
  • Toh K, Kukita T, Wu Z, Kukita A, Sandra F, Tang Q Y, et al. Possible involvement of MIP-1alpha in the recruitment of osteoclast progenitors to the distal tibia in rats with adjuvant-induced arthritis. Laboratory Investigations 2004; 84: 1092–1102
  • Terpos E, Politou M, Rahemtulla A. New insights into the pathophysiology and management of bone disease in multiple myeloma. British Journal of Haematology 2003; 123: 758–769
  • Choi S J, Oba Y, Gazitt Y, Alsina M, Cruz J, Anderson J, Roodman G D. Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease. Journal of Clinical Investigations 2001; 108: 1833–1841
  • Abe M, Hiura K, Wilde J, Moriyama K, Hashimoto T, Ozaki S, et al. Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma. Blood 2002; 100: 2195–2202
  • Oyajobi B O, Franchin G, Williams P J, Pulkrabek D, Gupta A, Munoz S, et al. Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease. Blood 2003; 102: 311–319
  • Oyajobi B O, Mundy G R. Macrophage inflammatory protein-1a: osteolytic and tumour-promoting effects in myeloma bone disease. Haematologica 2005; 90(Suppl1)42–43
  • Oba Y, Lee J W, Ehrlich L A, Chung H Y, Jelinek D F, Callander N S, et al. MIP-1alpha utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells. Experimental Hematology 2005; 33: 272–278
  • Hashimoto T, Abe M, Tanaka Y, Sekimoto E, Oshima T, Shibata H, et al. Macrophage inflammatory protein-1 may cause reciprocal regulation of osteoclast and dendritic cell differentiation from monocytes in myeloma. Haematologica 2005; 90(Suppl1)46
  • Hashimoto T, Abe M, Oshima T, Shibata H, Ozaki S, Inoue D, Matsumoto T. Ability of myeloma cells to secrete macrophage inflammatory protein (MIP)-1alpha and MIP-1beta correlates with lytic bone lesions in patients with multiple myeloma. British Journal of Haematology 2004; 125: 38–41
  • Terpos E, Politou M, Szydlo R, Goldman J M, Apperley J F, Rahemtulla A. Serum levels of macrophage inflammatory protein-1 alpha (MIP-1α) correlate with the extent of bone disease and survival in patients with multiple myeloma. British Journal of Haematology 2003; 123: 106–109
  • Magrangeas F, Nasser V, Avet-Loiseau H, Loriod B, Decaux O, Granjeaud S, et al. Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease. Blood 2003; 101: 4998–5006
  • Terpos E, Szydlo R, Apperley J F, Hatjiharissi E, Politou M, Meletis J, et al. Soluble receptor activator of nuclear factor-κB ligand (RANKL)/osteoprotegerin (OPG) ratio predicts survival in multiple myeloma. Proposal for a novel prognostic index. Blood 2003; 102: 1064–1069
  • Kraj M, Sokolowska U, Kruk B, Centkowski P. Correlation of osteoprotegerin and sRANKL concentrations in serum and bone marrow of multiple myeloma patients. Haematologica 2005; 90(Suppl1)193–194, (abstract)
  • Michigami T, Shimizu N, Williams P J, Niewolna M, Dallas S L, Mundy G R, Yoneda T. Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity. Blood 2000; 96: 1953–1960
  • Kuehl W M, Bergsagel P L. Multiple myeloma: evolving genetic events and host interactions. Natural Reviews in Cancer 2002; 2: 175–187
  • Su S, Mukaida N, Wang J, Zhang Y, Takami A, Nakao S, Matsushima K. Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1alpha by interacting mainly with a C-C chemokine receptor, CCR1. Blood 1997; 90: 605–611
  • Lentzsch S, Gries M, Janz M, Bargou R, Dorken B, Mapara M Y. Macrophage inflammatory protein 1-alpha (MIP-1 alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells. Blood 2003; 101: 3568–3573
  • Moller C, Stromberg T, Juremalm M, Nilsson K, Nilsson G. Expression and function of chemokine receptors in human multiple myeloma. Leukemia 2003; 17: 203–210

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.