Donor cell leukemia: A critical review

References

• Reichard K K, Zhang Q Y, Sanchez L, Hozier J, Viswanatha D, Foucar K. Acute myeloid leukemia of donor origin after allogeneic bone marrow transplantation for precursor T-cell acute lymphoblastic leukemia: case report and review of the literature. Am J Hematol 2006; 81: 178–185
   PubMed Web of Science ®Google Scholar
• Hertenstein B, Hambach L, Bacigalupo A, Schmitz N, McCann S, Slavin S, et al. Development of leukemia in donor cells after allogeneic stem cell transplantation—a survey of the European Group for Blood and Marrow Transplantation (EBMT). Haematologica 2005; 90: 969–975
   PubMed Web of Science ®Google Scholar
• Ruiz-Argüelles G J, Ruiz-Delgado G J, Garcés-Eisele J, Ruiz-Argüelles A, Pérez-Romano B, Reyes-Núñez V. Donor cell leukemia after non-myeloablative allogeneic stem cell transplantation: a single institution experience. Leuk Lymphoma 2006; 47: 1952–1955
   PubMed Web of Science ®Google Scholar
• Fialkow P J, Thomas E D, Bryant J I, Neiman P E. Leukaemic transformation of engrafted human marrow cells in vivo. Lancet 1971; 1: 251–255
   PubMed Web of Science ®Google Scholar
• Thomas E D, Bryant J I, Buckner C D, Clift R A, Fefer A, Johnson F L, et al. Leukaemic transformation of engrafted human marrow cells in vivo. Lancet 1972; 1: 1310–1313
   PubMed Web of Science ®Google Scholar
• Goh K, Klemperer M R. In vivo leukemic transformation: cytogenetic evidence of in vivo leukemic transformation of engrafted marrow cells. Am J Hematol 1977; 2: 283–290
   PubMed Web of Science ®Google Scholar
• Elfenbein G J, Brogaonkar D S, Bias W B, Burns W H, Saral R, Sensenbrenner L L, et al. Cytogenetic evidence for recurrence of acute myelogenous leukemia after allogeneic bone marrow transplantation in donor hematopoietic cells. Blood 1978; 52: 627–636
   PubMed Web of Science ®Google Scholar
• Newburger P E, Latt S A, Pesando J M, Gustashaw K, Powers M, Chaganti R S, O'Reilly R J. Leukemia relapse in donor cells after allogeneic bone-marrow transplantation. N Engl J Med 1981; 304: 712–714
   PubMed Web of Science ®Google Scholar
• Marmont A, Frassoni F, Bacigalupo A, Podesta M, Piaggio G, Van Lint M T, et al. Recurrence of Ph'-positive leukemia in donor cells after marrow transplantation for chronic granulocytic leukemia. N Engl J Med 1984; 310: 903–906
   PubMed Web of Science ®Google Scholar
• McCann S R, Lawler M, Humphries P, Bacigalupo A, Podesta M, Frassoni F, et al. Recurrence of Philadelphia chromosome-positive leukemia in donor cells after marrow transplantation for chronic granulocytic leukemia: confirmation by microsatellite studies. Blood 1992; 79: 2803–2805
   PubMed Web of Science ®Google Scholar
• Smith J L, Heerema N A, Provisor A J. Leukaemic transformation of engrafted bone marrow cells. Br J Haematol 1985; 60: 415–422
   PubMed Web of Science ®Google Scholar
• Witherspoon R P, Schubach W, Neiman P, Martin P, Thomas E D. Donor cell leukemia developing six years after marrow grafting for acute leukemia. Blood 1985; 65: 1172–1174
   PubMed Web of Science ®Google Scholar
• Zaccaria A, Rosti G, Testoni N, Arnold R, Bandini G, Becher R, et al. Chromosome studies in patients with acute nonlymphocytic or acute lymphocytic leukemia submitted to bone marrow transplantation—results of a European cooperative study. Cancer Genet Cytogenet 1987; 26: 51–58
   PubMed Web of Science ®Google Scholar
• Schmitz N, Johannson W, Schmidt G, von der Helm K, Loffler H. Recurrence of acute lymphoblastic leukemia in donor cells after allogeneic marrow transplantation associated with a deletion of the long arm of chromosome 6. Blood 1987; 70: 1099–1104
   PubMed Web of Science ®Google Scholar
• Feig S A, Dreazen O, Simon M, Wiley F, Schreck R, Gale R P. B cell acute lymphoblastic leukemia (ALL) in donor cells following bone marrow transplantation for T cell ALL. Bone Marrow Transplant 1988; 3: 331–337
   PubMed Web of Science ®Google Scholar
• Browne P V, Lawler M, Humphries P, McCann S R. Donor-cell leukemia after bone marrow transplantation for severe aplastic anemia. N Engl J Med 1991; 325: 710–713
   PubMed Web of Science ®Google Scholar
• Cullis J O, Marks D I, Schwarer A P, Barrett A J, Hows J M, Swirsky D M, Goldman J M. Relapse into blast crisis following bone marrow transplantation for chronic phase chronic myeloid leukaemia: a report of five cases. Br J Haematol 1992; 81: 378–382
   PubMed Web of Science ®Google Scholar
• Mouratidou M, Sotiropoulos D, Deremitzaki K, Spathas D H, Hoffbrand A V, Prentice H G, et al. Recurrence of acute leukemia in donor cells after bone marrow transplantation: documentation by in situ DNA hybridization. Bone Marrow Transplant 1993; 12: 77–80
   PubMed Web of Science ®Google Scholar
• Cransac M, Boiron J M, Merel P, Cony-Makhoul P, Marit G, Bernard P, et al. Burkitt-type acute lymphoblastic leukemia in donor cells after allogeneic bone marrow transplantation for acute nonlymphoblastic leukemia. Transplantation 1993; 56: 120–123
   Web of Science ®Google Scholar
• Katz F, Reeves B R, Alexander S, Kearney L, Chessells J. Leukaemia arising in donor cells following allogeneic bone marrow transplantation for beta thalassaemia demonstrated by immunological, DNA and molecular cytogenetic analysis. Br J Haematol 1993; 85: 326–331
   PubMed Web of Science ®Google Scholar
• Lowsky R, Fyles G, Minden M, Lipton J, Meharchand J, Tejpar I, et al. Detection of donor cell derived acute myelogenous leukaemia in a patient transplanted for chronic myelogenous leukaemia using fluorescence in situ hybridization. Br J Haematol 1996; 93: 163–165
   PubMed Web of Science ®Google Scholar
• Cooley L D, Sears D A, Udden M M, Harrison W R, Baker K R. Donor cell leukemia: report of a case occurring 11 years after allogeneic bone marrow transplantation and review of the literature. Am J Hematol 2000; 63: 46–53
   PubMed Web of Science ®Google Scholar
• Hambach L, Eder M, Dammann E, Battmer K, Stucki A, Heil G, et al. Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia. Bone Marrow Transplant 2001; 28: 705–707
   PubMed Web of Science ®Google Scholar
• Lawler M, Locasciulli A, Longoni D, Schiro R, McCann S R. Leukaemic transformation of donor cells in a patient receiving a second allogeneic bone marrow transplant for severe aplastic anaemia. Bone Marrow Transplant 2002; 29: 453–456
   PubMed Web of Science ®Google Scholar
• Au W Y, Chan E C, Siu L L, Lau T C, Lie A K, Ma S K, Kwong Y L. Leukaemic relapse of donor origin after allogeneic bone marrow transplantation from a donor who later developed bronchogenic carcinoma. Br J Haematol 2002; 119: 777–780
   PubMed Web of Science ®Google Scholar
• Gopcsa L, Barta A, Banyai A, Konya M, Pajor L, Foldi J, Paloczi K. Acute myeloid leukaemia of donor cell origin developing 5 years after allogeneic bone marrow transplantation for chronic myeloid leukaemia. Bone Marrow Transplant 2002; 29: 449–452
   PubMed Web of Science ®Google Scholar
• Brunstein C G, Hirsch B A, Hammerschmidt D, McGlennen R C, Nguyen P L, Verfaillie C M. Leukemia in donor cells after allogeneic hematopoietic stem cell transplant. Bone Marrow Transplant 2002; 29: 999–1003
   PubMed Web of Science ®Google Scholar
• Komeno Y, Kanda Y, Kandabashi K, Kawazu M, Goyama S, Takeshita M, et al. Reduced-intensity bone marrow transplantation from an alternative unrelated donor for myelodysplastic syndrome of first-donor origin. Am J Hematol 2003; 72: 220–222
   PubMed Web of Science ®Google Scholar
• Bielorai B, Deeg H J, Weintraub M, Neumann Y, Rosner E, Amariglio N, et al. B-cell lymphoma developing in the donor 9 years after donor-origin acute myeloid leukemia post bone marrow transplantation. Bone Marrow Transplant 2003; 31: 931–934
   PubMed Web of Science ®Google Scholar
• Haltrich I, Muller J, Szabo J, Kovacs G, Koos R, Poros A. Donor-cell myelodysplastic syndrome developing 13 years after marrow grafting for aplastic anemia. Cancer Genet Cytogenet 2003; 142: 124–128
   PubMed Web of Science ®Google Scholar
• Au W Y, Lam C C, Lie A K, Pang A, Kwong Y L. T-cell large granular lymphocyte leukemia of donor origin after allogeneic bone marrow transplantation. Am J Clin Pathol 2003; 120: 626–630
   PubMed Web of Science ®Google Scholar
• McCann S, Wright E. Donor leukaemia: perhaps a more common occurrence than we thought!. Bone Marrow Transplant 2003; 32: 455–457
   PubMed Web of Science ®Google Scholar
• Matsunaga T, Murase K, Yoshida M, Fujimi A, Iyama S, Kuribayashi K, et al. Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma. Am J Hematol 2005; 79: 294–298
   PubMed Web of Science ®Google Scholar
• Fraser C J, Hirsch B A, Dayton V, Creer M H, Neglia J P, Wagner J E, Baker K S. First report of donor cell-derived acute leukemia as a complication of umbilical cord blood transplantation. Blood 2005; 106: 4377–4380
   PubMed Web of Science ®Google Scholar
• Ataergin S, Arpaci F, Cetil T, Guran S, Yakicier C, Beyzadeoglu M, Ozet A. Donor cell leukemia in a patient developing 11 months after an allogeneic bone marrow transplantation for chronic myeloid leukemia. Am J Hematol 2006; 81: 370–373
   PubMed Web of Science ®Google Scholar
• Sala-Torra O, Hanna C, Loken M R, Flowers M ED, Maris M, Ladne P A, et al. Evidence of donor-derived hematologic malignancies after hematopoietic stem cell transplantation. Biol Blood Marrow Transpl 2006; 12: 511–517
   PubMed Web of Science ®Google Scholar
• Greaves M F. Cord blood donor cell leukemia in recipients. Leukemia 2006, 22 Jun, epub ahead of print
   PubMed Web of Science ®Google Scholar
• Sparkes M C, Crist M L, Sparkes R S, Gale R P, Feig S A. Gene markers in human bone marrow transplantation. Vox Sang 1977; 33: 202–205
   PubMed Web of Science ®Google Scholar
• Mathe G, Amiel J L, Schwarzenberg L, Cattan A, Schneider M, Devries M J, et al. Successful allogenic bone marrow transplantation in man: chimerism, induced specific tolerance and possible anti-leukemic effects. Blood 1965; 25: 179–196
   PubMed Web of Science ®Google Scholar
• Blume K G, Beutler E, Bross K J, Schmidt G M, Spruce W E, Teplitz R L. Genetic markers in human bone marrow transplantation. Am J Hum Genet 1980; 32: 414–419
   PubMed Web of Science ®Google Scholar
• Witherspoon R P, Schanfield M S, Storb R, Thomas E D, Giblett E R. Immunoglobulin production of donor origin after marrow transplantation for acute leukemia or aplastic anemia. Transplantation 1978; 26: 407–408
   PubMed Web of Science ®Google Scholar
• Schattenberg A, De Witte T, Salden M, Vet J, Van Dijk B, Smeets D, et al. Mixed hematopoietic chimerism after allogeneic transplantation with lymphocyte-depleted bone marrow is not associated with a higher incidence of relapse. Blood 1989; 73: 1367–1372
   PubMed Web of Science ®Google Scholar
• Bolan C D, Leitman S F, Griffith L M, Wesley R A, Procter J L, Stroncek D F, et al. Delayed donor red cell chimerism and pure red cell aplasia following major ABO-incompatible nonmyeloablative hematopoietic stem cell transplantation. Blood 2001; 98: 1687–1694
   PubMed Web of Science ®Google Scholar
• Thiede C. Diagnostic chimerism analysis after allogeneic stem cell transplantation: new methods and markers. Am J Pharmacogenomics 2004; 4: 177–187
   PubMedGoogle Scholar
• Stein J, Zimmerman P A, Kochera M, Strandjord S, Golden W, Simon M, et al. Origin of leukemic relapse after bone marrow transplantation: comparison of cytogenetic and molecular analyses. Blood 1989; 73: 2033–2040
   PubMed Web of Science ®Google Scholar
• Lawler S D, Baker M C, Harris H, Morgenstern G R. Cytogenetic studies on recipients of allogeneic bone marrow using the sex chromosomes as markers of cellular origin. Br J Haematol 1984; 56: 431–443
   PubMed Web of Science ®Google Scholar
• Mielcarek M, Bryant E, Loken M, Torok-Storb B, Storb R. Haemopoietic reconstitution by donor-derived myelodysplastic progenitor cells after haemopoietic stem cell transplantation. Br J Haematol 1999; 105: 361–365
   PubMed Web of Science ®Google Scholar
• Dewald G W, Schad C R, Christensen E R, Law M E, Zinsmeister A R, Stalboerger P G, et al. Fluorescence in situ hybridization with X and Y chromosome probes for cytogenetic studies on bone marrow cells after opposite sex transplantation. Bone Marrow Transplant 1993; 12: 149–154
   PubMed Web of Science ®Google Scholar
• Buno I, Nava P, Simon A, Gonzalez-Rivera M, Jimenez J L, Balsalobre P, et al. A comparison of fluorescent in situ hybridization and multiplex short tandem repeat polymerase chain reaction for quantifying chimerism after stem cell transplantation. Haematologica 2005; 90: 1373–1379
   PubMed Web of Science ®Google Scholar
• Jolkowska J, Pieczonka A, Strabel T, Boruczkowski D, Wachowiak J, Bader P, Witt M. Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization. BMC Blood Disord 2005; 5: 1–6
   PubMedGoogle Scholar
• Lo Y M, Tein M S, Lau T K, Haines C J, Leung T N, Poon P M, et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998; 62: 768–775
   PubMed Web of Science ®Google Scholar
• Fehse B, Chukhlovin A, Kuhlcke K, Marinetz O, Vorwig O, Renges H, et al. Real-time quantitative Y chromosome-specific PCR (QYCS-PCR) for monitoring hematopoietic chimerism after sex-mismatched allogeneic stem cell transplantation. J Hematother Stem Cell Res 2001; 10: 419–425
   PubMedGoogle Scholar
• Ugozzoli L, Yam P, Petz L D, Ferrara G B, Champlin R E, Forman S J, et al. Amplification by the polymerase chain reaction of hypervariable regions of the human genome for evaluation of chimerism after bone marrow transplantation. Blood 1991; 77: 1607–1615
   PubMed Web of Science ®Google Scholar
• Boerwinkle E, Xiong W J, Fourest E, Chan L. Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3’ hypervariable region. Proc Natl Acad Sci USA 1989; 86: 212–216
   PubMed Web of Science ®Google Scholar
• Schichman S A, Suess P, Vertino A M, Gray P S. Comparison of short tandem repeat and variable number tandem repeat genetic markers for quantitative determination of allogeneic bone marrow transplant engraftment. Bone Marrow Transplant 2002; 29: 243–248
   PubMed Web of Science ®Google Scholar
• Lawler M, Humphries P, McCann S R. Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction. Blood 1991; 77: 2504–2514
   PubMed Web of Science ®Google Scholar
• Scharf S J, Smith A G, Hansen J A, McFarland C, Erlich H A. Quantitative determination of bone marrow transplant engraftment using fluorescent polymerase chain reaction primers for human identity markers. Blood 1995; 85: 1954–1963
   PubMed Web of Science ®Google Scholar
• Kristt D, Israeli M, Narinski R, Or H, Yaniv I, Stein J, Klein T. Hematopoietic chimerism monitoring based on STRs: quantitative platform performance on sequential samples. J Biomol Tech 2005; 16: 380–391
   PubMedGoogle Scholar
• Hochberg E P, Miklos D B, Neuberg D, Eichner D A, McLaughlin S F, Mattes-Ritz A, et al. A novel rapid single nucleotide polymorphism (SNP)-based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation. Blood 2003; 101: 363–369
   PubMed Web of Science ®Google Scholar
• Roth M S, Antin J H, Bingham E L, Ginsburg D. Use of polymerase chain reaction-detected sequence polymorphisms to document engraftment following allogeneic bone marrow transplantation. Transplantation 1990; 49: 714–720
   PubMed Web of Science ®Google Scholar
• Kroger N, Zagrivnaja M, Schwartz S, Badbaran A, Zabelina T, Lioznov M, et al. Kinetics of plasma-cell chimerism after allogeneic stem cell transplantation by highly sensitive real-time PCR based on sequence polymorphism and its value to quantify minimal residual disease in patients with multiple myeloma. Exp Hematol 2006; 34: 688–694
   PubMed Web of Science ®Google Scholar
• Alizadeh M, Bernard M, Danic B, Dauriac C, Birebent B, Lapart C, et al. Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction. Blood 2002; 99: 4618–4625
   PubMed Web of Science ®Google Scholar
• Bader P, Niethammer D, Willasch A, Kreyenberg H, Klingebiel T. How and when should we monitor chimerism after allogeneic stem cell transplantation?. Bone Marrow Transplant 2005; 35: 107–119
   PubMed Web of Science ®Google Scholar
• Guettier C, Sebagh M, Buard J, Feneux D, Ortin-Serrano M, Gigou M, et al. Male cell microchimerism in normal and diseased female livers from fetal life to adulthood. Hepatology 2005; 42: 35–43
   PubMed Web of Science ®Google Scholar
• Maloney S, Smith A, Furst D E, Myerson D, Rupert K, Evans P C, Nelson J L. Microchimerism of maternal origin persists into adult life. J Clin Invest 1999; 104: 41–47
   PubMed Web of Science ®Google Scholar
• Uehara S, Nata M, Nagae M, Sagisaka K, Okamura K, Yajima A. Molecular biologic analyses of tetragametic chimerism in a true hermaphrodite with 46,XX/46,XY. Fertil Steril 1995; 63: 189–192
   PubMed Web of Science ®Google Scholar
• Beck O, Seidl C, Lehrnbecher T, Kreyenberg H, Schwabe D, Klingebiel T, et al. Quantification of chimerism within peripheral blood, bone marrow and purified leukocyte subsets: comparison of singleplex and multiplex PCR amplification of short tandem repeat (STR) loci. Eur J Haematol 2006; 76: 237–244
   PubMed Web of Science ®Google Scholar
• Najfeld V, Burnett W, Vlachos A, Scigliano E, Isola L, Fruchtman S. Interphase FISH analysis of sex-mismatched BMT utilizing dual color XY probes. Bone Marrow Transplant 1997; 19: 829–834
   PubMed Web of Science ®Google Scholar
• Antin J H, Childs R, Filipovich A H, Giralt S, Mackinnon S, Spitzer T, Weisdorf D. Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation: recommendations from a workshop at the 2001 Tandem Meetings of the International Bone Marrow Transplant Registry and the American Society of Blood and Marrow Transplantation. Biol Blood Marrow Transplant 2001; 7: 473–485
   PubMed Web of Science ®Google Scholar
• Chou P M, Olszewski M, Huang W, Silva M, Kletzel M. Platelet chimerism by polymerase chain reaction (PCR) utilizing variable number of tandem repeats (VNTR) in allogeneic stem cell transplant in children: a new novel approach to full chimerism analysis. Bone Marrow Transplant 2003; 32: 825–828
   Google Scholar
• Lanfranchi A, Verardi R, Tettoni K, Neva A, Mazzolari E, Pennacchio M, et al. Haploidentical peripheral blood and marrow stem cell transplantation in nine cases of primary immunodeficiency. Haematologica 2000; 85: 41–46
   PubMedGoogle Scholar
• Yamazaki S, Takahashi H, Fujii H, Miyamae T, Mori M, Fujioka K, et al. Split chimerism after allogeneic bone marrow transplantation in Chediak-Higashi syndrome. Bone Marrow Transplant 2003; 31: 137–140
   PubMed Web of Science ®Google Scholar
• Holmgren L, Szeles A, Rajnavolgyi E, Folkman J, Klein G, Ernberg I, Falk K I. Horizontal transfer of DNA by the uptake of apoptotic bodies. Blood 1999; 93: 3956–3963
   PubMed Web of Science ®Google Scholar
• Bergsmedh A, Szeles A, Henriksson M, Bratt A, Folkman M J, Spetz A L, Holmgren L. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc Natl Acad Sci USA 2001; 98: 6407–6411
   PubMed Web of Science ®Google Scholar
• Bergsmedh A, Ehnfors J, Kawane K, Motoyama N, Nagata S, Holmgren L. DNase II and the Chk2 DNA damage pathway form a genetic barrier blocking replication of horizontally transferred DNA. Mol Cancer Res 2006; 4: 187–195
   PubMed Web of Science ®Google Scholar
• Mortensen K, Lichtenberg J, Thomsen P D, Larsson L I. Spontaneous fusion between cancer cells and endothelial cells. Cell Mol Life Sci 2004; 61: 2125–2131
   PubMed Web of Science ®Google Scholar
• Pawelek J M. Tumour-cell fusion as a source of myeloid traits in cancer. Lancet Oncol 2005; 6: 988–993
   PubMed Web of Science ®Google Scholar
• Chakraborty A, Lazova R, Davies S, Backvall H, Ponten F, Brash D, Pawelek J. Donor DNA in a renal cell carcinoma metastasis from a bone marrow transplant recipient. Bone Marrow Transplant 2004; 34: 183–186
   PubMed Web of Science ®Google Scholar
• Dewald G, Stallard R, Al Saadi A, Arnold S, Bader P I, Blough R, et al. A multicenter investigation with interphase fluorescence in situ hybridization using X- and Y-chromosome probes. Am J Med Genet 1998; 76: 318–326
   PubMed Web of Science ®Google Scholar
• Buno I, Anta B, Moreno-Lopez E, Balsalobre P, Balas A, Garcia-Sanchez F, et al. Lineage-specific chimaerism quantification after T-cell depleted peripheral blood stem cell transplantation. Leuk Lymphoma 2003; 44: 659–667
   PubMed Web of Science ®Google Scholar
• Herens C, Brasseur E, Jamar M, Vierset L, Schoenen I, Koulischer L. Loss of the Y chromosome in bone marrow cells: results on 1907 consecutive cases of leukaemia and preleukaemia. Clin Lab Haematol 1999; 21: 17–20
   PubMedGoogle Scholar
• Wiktor A, Rybicki B A, Piao Z S, Shurafa M, Barthel B, Maeda K, Van Dyke D L. Clinical significance of Y chromosome loss in hematologic disease. Genes Chromosomes Cancer 2000; 27: 11–16
   PubMed Web of Science ®Google Scholar
• Spinelli O, Giussani U, Borleri G, Lazzari M, Michelato A, Dotti G, et al. Need for an accurate molecular diagnosis to assess the donor origin of leukemia relapse after allogeneic stem cell transplantation. Haematologica 2000; 85: 1153–1157
   Google Scholar
• Wong K F, Chan J K, Yu P H, So C C. A man with natural killer cell lymphoma showing 46,XX and deletion 6q. Cancer Genet Cytogenet 1999; 112: 165–168
   PubMed Web of Science ®Google Scholar
• Mossallam G I, Smith A G, McFarland C. Comparison of variable number tandem repeat and short tandem repeat genetic markers for qualitative and quantitative chimerism analysis post allogeneic stem cell transplantation. J Egypt Natl Canc Inst 2005; 17: 103–113
   Google Scholar
• Gill P, Whitaker J, Flaxman C, Brown N, Buckleton J. An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA. Forensic Sci Int 2000; 112: 17–40
   PubMed Web of Science ®Google Scholar
• Gill P, Curran J, Elliot K. A graphical simulation model of the entire DNA process associated with the analysis of short tandem repeat loci. Nucleic Acids Res 2005; 33: 632–643
   PubMed Web of Science ®Google Scholar
• Hauge X Y, Litt M. A study of the origin of ‘shadow bands’ seen when typing dinucleotide repeat polymorphisms by the PCR. Hum Mol Genet 1993; 2: 411–415
   PubMed Web of Science ®Google Scholar
• Walsh P S, Fildes N J, Reynolds R. Sequence analysis and characterization of stutter products at the tetranucleotide repeat locus vWA. Nucleic Acids Res 1996; 24: 2807–2812
   PubMed Web of Science ®Google Scholar
• Weber J L, May P E. Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. Am J Hum Genet 1989; 44: 388–396
   PubMed Web of Science ®Google Scholar
• Levinson G, Gutman G A. High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12. Nucleic Acids Res 1987; 15: 5323–5338
   PubMed Web of Science ®Google Scholar
• Levinson G, Gutman G A. Slipped-strand mispairing: a major mechanism for DNA sequence evolution. Mol Biol Evol 1987; 4: 203–221
   PubMed Web of Science ®Google Scholar
• Schlotterer C, Tautz D. Slippage synthesis of simple sequence DNA. Nucleic Acids Res 1992; 20: 211–215
   PubMed Web of Science ®Google Scholar
• Urquhart A, Chiu C T, Clayton T M, Downes T, Frazier R RE, Jones S, et al. Multiplex STR systems with fluorescent detection as human identification markers. Proceedings from the 5th International Symposium on Human Identification
   Google Scholar
• Gusmao L, Amorim A, Prata M J, Pereira L, Lareu M V, Carracedo A. Failed PCR amplifications of MBP-STR alleles due to polymorphism in the primer annealing region. Int J Legal Med 1996; 108: 313–315
   PubMed Web of Science ®Google Scholar
• Lygo J E, Johnson P E, Holdaway D J, Woodroffe S, Whitaker J P, Clayton T M, et al. The validation of short tandem repeat (STR) loci for use in forensic casework. Int J Leg Med 1994; 107: 77–89
   PubMed Web of Science ®Google Scholar
• Borst A, Box A T, Fluit A C. False-positive results and contamination in nucleic acid amplification assays: suggestions for a prevent and destroy strategy. Eur J Clin Microbiol Infect Dis 2004; 23: 289–299
   PubMed Web of Science ®Google Scholar
• Kwok S, Higuchi R. Avoiding false positives with PCR. Nature 1989; 339: 237–238
   PubMed Web of Science ®Google Scholar
• Technical Working Group on DNA Methods. Guidelines for a quality assurance program for DNA analysis. Crime Laboratory Digest 1995; 22: 21–50
   Google Scholar
• Zhou M, Sheldon S, Akel N, Killeen A A. Chromosomal aneuploidy in leukemic blast crisis: a potential source of error in interpretation of bone marrow engraftment analysis by VNTR amplification. Mol Diagn 1999; 4: 153–157
   PubMedGoogle Scholar
• Schichman S A, Lin P, Gilbrech L J, Gray P S, Wilson C S, Sawyer J R. Bone marrow transplant engraftment analysis with loss of an informative allele. J Mol Diagn 2002; 4: 230–232
   PubMed Web of Science ®Google Scholar
• Rubocki R J, Duffy K J, Shepard K L, McCue B J, Shepherd S J, Wisecarver J L. Loss of heterozygosity detected in a short tandem repeat (STR) locus commonly used for human DNA identification. J Forensic Sci 2000; 45: 1087–1089
   PubMed Web of Science ®Google Scholar
• Stark B, Jeison M, Gobuzov R, Krug H, Glaser-Gabay L, Luria D, et al. Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization. Cancer Genet Cytogenet 2001; 128: 108–113
   PubMed Web of Science ®Google Scholar
• Gancberg D, Dargent J L, Verhest A, Kentos A, Feremans W, Lohrisch C, Kornreich A. Near haploid blast phase in a chronic myeloid leukemia detected by fluorescence in situ hybridization using a BCR-ABL probe. Cancer Genet Cytogenet 2001; 128: 172–174
   PubMed Web of Science ®Google Scholar
• Cibull M L, Thompson M E, Smith L, Jennings C D, Doukas M A, Pavlik E J, Powell D E. Marked hypodiploidy in blast phase chronic myelogenous leukemia: report of a case and review of the literature. Am J Hematol 1987; 24: 293–299
   PubMed Web of Science ®Google Scholar
• Weber J L, David D, Heil J, Fan Y, Zhao C, Marth G. Human diallelic insertion/deletion polymorphisms. Am J Hum Genet 2002; 71: 854–862
   PubMed Web of Science ®Google Scholar
• Bhangale T R, Rieder M J, Livingston R J, Nickerson D A. Comprehensive identification and characterization of diallelic insertion-deletion polymorphisms in 330 human candidate genes. Hum Mol Genet 2005; 14: 59–69
   PubMed Web of Science ®Google Scholar
• Maas F, Schaap N, Kolen S, Zoetbrood A, Buno I, Dolstra H, et al. Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms. Leukemia 2003; 17: 621–629
   PubMedGoogle Scholar
• Sachidanandam R, Weissman D, Schmidt S C, Kakol J M, Stein L D, Marth G, et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 2001; 409: 928–933
   PubMed Web of Science ®Google Scholar
• Agrawal S, Khan F, Talwar S, Nityanand S. Short tandem repeat technology has diverse applications: Individual identification, phylogenetic reconstruction and chimerism based post haematopoietic stem cell transplantation graft monitoring. Indian J Med Sci 2004; 58: 297–304
   PubMedGoogle Scholar
• Thiede C, Bornhauser M, Ehninger G. Evaluation of STR informativity for chimerism testing – comparative analysis of 27 STR systems in 203 matched related donor recipient pairs. Leukemia 2004; 18: 248–254
   PubMed Web of Science ®Google Scholar
• van Leeuwen J E, van Tol M J, Bodzinga B G, Wijnen J T, van der Keur M, Joosten A M, et al. Detection of mixed chimaerism in flow-sorted cell subpopulations by PCR-amplified VNTR markers after allogeneic bone marrow transplantation. Br J Haematol 1991; 79: 218–225
   PubMed Web of Science ®Google Scholar
• Walker S E. Early appearance of abnormally migrating serum IgM in control and cyclophosphamide-treated NZB/NZW mice. J Rheumatol 1982; 9: 183–188
   PubMed Web of Science ®Google Scholar
• Diebold J. Reactive lymph-node hyperplasia and pseudolymphomas with hypergammaglobulinemia. II. Pseudolymphoma and prelymphoma Ann Pathol 1984; 4: 3–17
   PubMed Web of Science ®Google Scholar
• Talal N, Bunim J J. The development of malignant lymphoma in the course of Sjögren's syndrome. Am J Med 1964; 36: 529–540
   PubMed Web of Science ®Google Scholar
• Kowenz-Leutz E, Leutz A. A C/EBP-beta isoform recruits the SWI/SNF complex to activate myeloid genes. Molecular Cell 1999; 4: 735–743
   PubMed Web of Science ®Google Scholar
• Calkhoven C F, Muller C, Leutz A. Translational control of C/EBP alpha and C/EBP beta isoform expression. Genes Dev 2000; 14: 1920–1932
   PubMed Web of Science ®Google Scholar
• Pedersen T A, Kowenz-Leutz E, Leutz A, Nerlov C. Cooperation between C/EBPalpha TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation. Genes Dev 2001; 15: 3208–3216
   PubMed Web of Science ®Google Scholar
• Calkhoven C F, Muller C, Leutz A. Translational control of gene expression and disease. Trends Mol Med 2002; 8: 577–583
   PubMed Web of Science ®Google Scholar
• Calkhoven C F, Muller C, Martin R, Krosl G, Pietsch H, Hoang T, Leutz A. Translational control of SCL-isoform expression in hematopoietic lineage choice. Genes Dev 2003; 17: 959–964
   PubMed Web of Science ®Google Scholar
• Muller C, Calkhoven C F, Sha X, Leutz A. The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest. J Biol Chem 2004; 279: 7353–7358
   PubMed Web of Science ®Google Scholar
• Mo X, Kowenz-Leutz E, Xu H, Leutz A. Ras induces mediator complex exchange on C/EBP beta. Mol Cell 2004; 13: 241–250
   PubMed Web of Science ®Google Scholar
• Begay V, Smink J, Leutz A. Essential requirement of CCAAT/Enhancer Binding Proteins (C/EBP) in embryogenesis. Mol Cell Biol 2004; 24: 9744–9751
   PubMed Web of Science ®Google Scholar
• Murugesan G, Aboudola S, Szpurka H, Verbic M A, Maciejewski J P, Tubbs R R, Hsi E D. Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis. Am J Clin Pathol 2006; 125: 625–633
   PubMed Web of Science ®Google Scholar
• Schuler F, Hirt C, Dolken G. Chromosomal translocation t(14;18) in healthy individuals. Semin Cancer Biol 2003; 13: 203–209
   PubMed Web of Science ®Google Scholar
• Janz S, Potter M, Rabkin C S. Lymphoma- and leukemia-associated chromosomal translocation in healthy individuals. Genes Chromosomes Cancer 2003; 36: 211–223
   PubMed Web of Science ®Google Scholar
• Uckun F M, Herman-Hatten K, Crotty M L, Sensel M G, Sather H N, Tuel-Ahlgren L, et al. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation. Blood 1998; 92: 810–821
   PubMed Web of Science ®Google Scholar
• Deeg H J, Socie G. Malignancies after hematopoietic stem cell transplantation: many questions, some answers. Blood 1998; 91: 1833–1844
   PubMed Web of Science ®Google Scholar
• Weiss R, Mitrou P, Arasteh K, Schuermann D, Hentrich M, Duehrsen U, et al. Acquired immunodeficiency syndrome-related lymphoma: simultaneous treatment with combined cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy and highly active antiretroviral therapy is safe and improves survival – results of the German Multicenter Trial. Cancer 2006; 106: 1560–1568
   PubMed Web of Science ®Google Scholar
• Weissman I L, McGrath M S, Tamura G. The receptor-mediated leukemogenesis hypothesis: a model of retroviral oncogenesis by viral stimulation of cell-surface receptors. Life Sci Res Rep 1985; 30: 235–249
   Google Scholar
• Bergsmedh A, Szeles A, Henriksson M, Bratt A, Folkman M J, Spetz A L, Holmgren L. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc Nat Acad Sci USA 2001; 98: 6407–6411
   PubMed Web of Science ®Google Scholar
• McCann S R, Lawler M, Bacigalupo A. Recurrence of Philadelphia chromosome-positive leukemia in donor cells after bone marrow transplantation for chronic granulocytic leukemia. Leuk Lymphoma 1993; 10: 419–425
   PubMed Web of Science ®Google Scholar
• Pedersen-Bjergaard J. Insight into leukemogenesis from therapy-related leukemia. N Eng J Med 2005; 352: 1591–1594
   PubMed Web of Science ®Google Scholar
• Karpinets T V, Foy B D. Tumorigenesis: the adaptation of mammalian cells to sustained stress environment by epigenetic alterations and succeeding matched mutations. Carcinogenesis 2005; 26: 1323–1334
   Google Scholar
• Kraut L, Trebeljahr G, Thiele B, Fauser A A. Donor cell-derived myelodysplastic syndrome in a patient 7 years after unrelated allogeneic HLA-mismatched transplantation for Ph+ chronic myeloid leukemia. Bone Marrow Transplant 2005; 36: 737
   PubMed Web of Science ®Google Scholar
• Turner S D, Alexander D R. Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cells. Leukemia 2006; 20: 572–582
   PubMed Web of Science ®Google Scholar
• Haegert D G. Analysis of threshold liability model provides new understanding of causation of autoimmune diseases. Med Hypotheses 2004; 63: 257–261
   PubMed Web of Science ®Google Scholar