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Letter to the Editor

Chromosomal abnormalities in chronic myeloid leukemia: Evidence of a hierarchy in imatinib treated cells

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Pages 1029-1031 | Received 18 Sep 2006, Accepted 02 Jan 2007, Published online: 01 Jul 2009

References

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  • Feldman E, Najfeld V, Schuster M, Roboz G, Chadburn A, Silver R T. The emergence of Ph-, trisomy-8+ cells in patients with chronic myeloid leukemia treated with imatinib mesylate. Exp Hematol 2003; 31: 702–707
  • Terre C, Eclache V, Rousselot P, Imbert M, Charrin C, Gervais C, et al. Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia. Leukemia 2004; 18: 1340–1346
  • Medina J, Kantarjian H, Talpaz M, O'Brien S, Garcia-Manero G, Giles F, et al. Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during Imatinib Mesylate therapy in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase. Cancer 2003; 98: 1905–1911
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  • Andersen M K, Pedersen-Bjergaard J, Kjeldsen L, Dufva I H, Brøndum-Nielsen K. Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8. Leukemia 2002; 16: 1390–1393
  • Bacher U, Hochhaus A, Berger U, Hiddemann W, Hehlmann R, Haferlach T, Schoch C. Clonal aberrations in Philadelphia chromosome negative hematopoiesis chronic myeloid leukemia treated with imatinib or interferon alpha. Leukemia 2005; 19: 460–463

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