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Original

Homoharringtonine-induced apoptosis of MDS cell line MUTZ-1 cells is mediated by the endoplasmic reticulum stress pathway

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Pages 964-977 | Received 25 Sep 2006, Accepted 13 Jan 2007, Published online: 01 Jul 2009

References

  • Pattacini L, Mancini M, Mazzacurati L, Brusa G, Benvenuti M, Martinelli G, et al. Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase. Leuk Res 2004; 28: 191–202
  • Araki E, Oyadomari S, Mori M. Impact of endoplasmic reticulum stress pathway on pancreatic β-cells and diabetes mellitus. Exp Biol Med 2003; 228: 1213–1217
  • Tfsutsumi S, Gotoh T, Tomisato W. Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis. Cell Death Differ 2004; 11: 1009–1016
  • Lee A H, Iwakoshi N N, Glimcher L H. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 2003; 23: 7448–7459
  • Li J, Lee A S. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med 2006; 6: 45–54
  • Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11: 381–389
  • Wang X Z, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science 1996; 272: 1347–1349
  • Bonilla M, Nastase K K, Cunningham K W. Essential role of calcineurin in response to endoplasmic reticulum stress. EMBO J 2002; 21: 2343–2353
  • Mattson M P, LaFerla F M, Chan S L, Leissring M A, Shepel P N, Geiger J D. Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci 2000; 23: 222–229
  • Mufti G, List A F, Gore S D, Ho A Y. Myelodysplastic syndrome. Hematology Am Soc Hematol Educ Program 2003; 176–199
  • Look A T. Molecular pathogenesis of MDS. Hematology Am Soc Hematol Educ Program 2005; 156–160
  • Zhou D C, Zittoun R, Marie J P. Homoharringtonine: an effective new natural product in cancer chemotherapy. Bull Cancer 1995; 82: 987–995
  • Cai Z, Bao H Y, Lin M F. Correlation between survivin mRNA expression and homoharringtonine-induced apoptosis of malignant hematopoietic cells. Chin Med J (Engl) 2005; 118: 548–554
  • Lund P K, Namork E, Brorson S H, Westvik A B, Joo G B, Ovstebo R, et al. The fate of monocytes during 24 h of culture as revealed by flow cytometry and electron microscopy. J Immunol Methods 2002; 270: 63–76
  • Guo W X, Pye Q N, Williamson K S, Stewart C A, Hensley K L, Kotake Y, et al. Mitochondrial dysfunction in choline eficiency-induced apoptosis in cultured rat hepatocytes. Free Radic Biol Med 2005; 39: 641–650
  • Wang Y, Perchellet E M, Ward M M, Lou K, Hua D H, Perchellet J P. Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. Anticancer Drugs 2005; 16: 953–967
  • Farquharson C, Lester D, Seawright E, Jefferies D, Houston B. Microtubules are potential regulators of growth-plate chondrocyte differentiation and hypertrophy. Bone 1999; 25: 405–412
  • Houston B, Seawright E, Jefferies D, Hoogland E, Lester D, Whitehead C C, et al. Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes. Biochim Biophys Acta 1999; 1448: 500–506
  • Jefferies D, Houston B, Lester D, Whitehead C C, Thorp B H, Botman M, et al. Expression patterns of chondrocyte genes cloned by differential display in tibial dyschondroplasia. Biochim Biophys Acta 2000; 1501: 180–188
  • Thornberry N A, Lazebnik Y. Caspase: enemies within. Science 1998; 281: 1312–1316
  • Slichenmyer W J, Von Hoff D D. New natural products in cancer chemotherapy. J Clin Pharmacol 1990; 30: 770–788
  • Stewart J A, Krakoff I H. Homoharringtonine: a phase I evaluation. Invest New Drugs 1985; 3: 279–286
  • Savaraj N, Lu K, Dimery I, Feun L G, Burgess M, Keating M, et al. Clinical pharmacology of homoharringtonine. Cancer Treat Rep 1986; 70: 1403–1407
  • Kantarjian H M, Keating M J, Walters R S, Koller C A, McCredie K B, Freireich E J. Phase II study of low-dose continuous infusion homoharringtonine in refractory acute myelogenous leukemia. Cancer 1989; 63: 813–817
  • Gulow K, Bienert D, Haas I G. BiP is feed-back regulated by control of protein translation efficiency. J Cell Sci 2002; 115: 2443–2452
  • O'Brien S, Kantarjian H, Koller C, Feldman E, Beran M, Andreeff M, et al. Sequential homoharringtonine and interferon-alpha in the treatment of early chronic phase chronic myelogenous leukemia. Blood 1999; 93: 4149–4153
  • Cephalotaxus Research Coordinating Group. Cephalotaxine esters in the treatment of acute leukemia. A preliminary clinical assessment. Chin Med J 1976; 2: 263–272
  • Pettit E J, Hallett M B. Early Ca2+ signalling events in neutrophils detected by rapid confocal laser scanning. Biochem J 1995; 310(Part 2)445–448
  • Shen Z Y, Shen W Y, Chen M H, Shen J, Cai W J, Yi Z. Nitric oxide and calcium ions in apoptotic esophageal carcinoma cells induced by arsenite. World J Gastroenterol 2002; 8: 40–43
  • Nakano T, Watanabe H, Ozeki M, Asai M, Katoh H, Satoh H, et al. Endoplasmic reticulum Ca2+ depletion induces endothelial cell apoptosis independently of caspase-12. Cardiovasc Res 2006; 69: 908–915
  • Nawrocki S T, Carew J S, Pino M S, Highshaw R A, Dunner K, Jr, Huang P, et al. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res 2005; 65: 11658–11666
  • Cardozo A K, Ortis F, Storling J, Feng Y M, Rasschaert J, Tonnesen M, et al. Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells. Diabetes 2005; 54: 452–461
  • Grover A K, Samson S E, Misquitta C M. Sarco(endo)plasmic reticulum Ca2+ pump isoform SERCA3 is more resistant than SERCA2b to peroxide. Am J Physiol 1997; 73(2 Part 1)C420–C425
  • Gaspers L D, Thomas A P. Calcium signaling in liver. Cell Calcium 2005; 38: 329–342
  • Kwan H Y, Leung P C, Huang Y, Yao X. Depletion of intracellular Ca2+ stores sensitizes the flow-induced Ca2+ influx in rat endothelial cells. Circ Res 2003; 92: 286–292
  • Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11: 381–389
  • Tajiri S, Oyadomari S, Yano S. Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP. Cell Death Differ 2004; 11: 403–415
  • Cai Z, Lin M, Wuchter C. Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation. Leukemia 2001; 15: 567–575
  • Gajkowska B, Wojewodzka U, Gajda J. Translocation of Bax and Bid to mitochondria, endoplasmic reticulum and nuclear envelope: possible control points in apoptosis. J Mol Histol 2004; 35: 11–19

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