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Letter to the Editor

Unusual profiles of pediatric acute lymphoblastic leukemia with MLL gene rearrangement

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Pages 2083-2086 | Received 27 Jun 2007, Accepted 01 Aug 2007, Published online: 01 Jul 2009

References

  • Armstrong S A, Staunton J E, Silverman L B, Pieters R, den Boer M L, Minden M D, et al. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet 2002; 30: 41–47
  • Kuefer M U, Chinwalla V, Zeleznik-Le N J, Behm F G, Naeve C W, Rakestraw K M, et al. Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14). Oncogene 2003; 22: 1418–1424
  • Gill Super H J, Rothberg P G, Kobayashi H, Freeman A I, Diaz M O, Rowley J D. Clonal, nonconstitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: in utero chromosome rearrangement of 11q23. Blood 1994; 83: 641–644
  • Popovic R, Zeleznik-Le N J. MLL: how complex does it get?. J Cell Biochem 2005; 95: 234–242
  • Ferrando A A, Armstrong S A, Neuberg D S, Sallan S E, Silverman L B, Korsmeyer S J, et al. Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 2003; 102: 262–268
  • Ernst P, Wang J, Korsmeyer S J. The role of MLL in hematopoiesis and leukemia. Curr Opin Hematol 2002; 9: 282–287
  • Attarbaschi A, Mann G, Konig M, Steiner M, Strehl S, Schreiberhuber A, et al. Mixed lineage leukemia-rearranged childhood pro-B and CD10-negative pre-B acute lymphoblastic leukemia constitute a distinct clinical entity. Clin Cancer Res 2006; 12: 2988–2994
  • Kolomietz E, Al-Maghrabi J, Brennan S, Karaskova J, Minkin S, Lipton J, et al. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis. Blood 2001; 97: 3581–3588
  • Styczynski J, Czyzewski K, Wysocki M. Ex vivo activity of thalidomide in childhood acute leukemia. Leuk Lymphoma 2006; 47: 1123–1128
  • Janssen J W, Ludwig W D, Borkhardt A, Spadinger U, Rieder H, Fonatsch C, et al. Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission. Blood 1994; 84: 3835–3842
  • Chervinsky D S, Sait S N, Nowak N J, Shows T B, Aplan P D. Complex MLL rearrangement in a patient with T-cell acute lymphoblastic leukemia. Genes Chromosomes Cancer 1995; 14: 76–84
  • Hayette S, Tigaud I, Maguer-Satta V, Bartholin L, Thomas X, Charrin C, et al. Recurrent involvement of the MLL gene in adult T-lineage acute lymphoblastic leukemia. Blood 2002; 99: 4647–4649
  • Moorman A V, Richards S, Harrison C J. Involvement of the MLL gene in T-lineage acute lymphoblastic leukemia. Blood 2002; 100: 2273–2274
  • Raimondi S C, Frestedt J L, Pui C H, Downing J R, Head D R, Kersey J H, et al. Acute lymphoblastic leukemias with deletion of 11q23 or a novel inversion (11)(p13q23) lack MLL gene rearrangements and have favorable clinical features. Blood 1995; 86: 1881–1886
  • Pieters R, den Boer M L, Durian M, Janka G, Schmiegelow K, Kaspers G J, et al. Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia – implications for treatment of infants. Leukemia 1998; 12: 1344–1348

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