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Letter to the Editor

Acute myeloid leukemia with associated translocation t(15;17) and 11q23/MLL abnormality

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Pages 592-595 | Received 10 Oct 2007, Accepted 19 Dec 2007, Published online: 01 Jul 2009

References

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  • Cox M C, Panetta P, Lo-Coco F, Del Poeta G, Venditti A, Maurillo L, et al. Chromosomal aberration of the 11q23 locus in acute leukemia and frequency of MLL gene translocation results in 378 adult patients. Am J Clin Pathol 2004; 122: 298–306
  • Schoch C, Schnittger S, Klaus M, Kern W, Hiddemann W, Haferlach T. AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases. Blood 2003; 102: 2395–2402
  • Dubé S, Fetni R, Hazourli S, Champagne M, Lemieux N. Rearrangement of the MLL gene and a region proximal to the RARα gene in a case of acute myelocytic leukemia M5 with a t(11;17)(q23;q21). Cancer Genetics Cytogenetics 2003; 145: 54–59
  • De Botton A, Chevret S, Sanz M, Dombret H, Thomas X, Guerci A, et al. Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial. Br J Haematol 2000; 111: 801–806
  • Hernandez J M, Martin G, Gutierrez N C, Cervera J, Ferro M T, Calasanz M J, et al. Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anthracyclin based protocol. A report of the Spanish group Pethema. Haematologica 2001; 86: 807–813
  • Megonigal M D, Rappaport E F, Jones D H, Williams T M, Lovett B D, Kelly K M, et al. t(11;22)(q23;q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of delection in DiGeorge and velocardiofacial syndromes. Proc Natl Acad Sci USA 1998; 95: 6413–6418

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