87
Views
11
CrossRef citations to date
0
Altmetric
Focused Reviews in CML

Immunotherapeutic approaches in chronic myelogenous leukemia

, , , , , & show all
Pages 629-634 | Published online: 01 Jul 2009

References

  • Molldrem J J, Lee P P, Wang C, Felio K, Kantarjian H M, Champlin R E, et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med 2000; 6: 1018–1023
  • Gannage M, Abel M, Michallet A S, Delluc S, Lambert M, Giraudier S, et al. Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy. J Immunol 2005; 174: 8210–8218
  • Bocchia M, Wentworth P A, Southwood S, Sidney J, McGraw K, Scheinberg D A, et al. Specific binding of leukemia oncogene fusion protein peptides to HLA Class I molecules. Blood 1995; 85: 2680–2684
  • Bocchia M, Korontsvit T, Xu Q, Mackinnon S, Yang S Y, Sette A, et al. Specific human cellular immunity to bcr-abl oncogene-derived peptides. Blood 1996; 87: 3587–3592
  • Yotnda P, Firat P, Garcia-Pons F, Garcia Z, Gourru G, Vernant J P, et al. Cytotoxic T-cell response against the chimeric p210 BCRABL protein in patients with chronic myelogenous leukemia. J Clin Invest 1998; 101: 2290–2296
  • Buzyn A, Ostankovitch M, Zerbib A, Kemula M, Connan F, Varet B, et al. Peptides derived from the whole sequence of BCRABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes. Eur J Immunol 1997; 27: 2066–2072
  • Clark R E, Dodi I A, Hill S C, Lill J R, Aubert G, MacIntyre A R, et al. Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein. Blood 2001; 98: 2887–2893
  • Posthuma E FM, Falkenburg J HF, Apperley J F. HLA-B8 and HLA-A3 coexpressed with HLA-B8 are associated with a reduced risk of the development of chronic myeloid leukaemia. Blood 1999; 93: 3863–3865
  • Pinilla-Ibarz J, Cathcart K, Korontsvit T, Soignet S, Bocchia M, Caggiano J, et al. Vaccination of patients with chronic myelogenous leukemia with bcr-abl oncogene breakpoint fusion peptides generates specific immune response. Blood 2000; 95: 1781–1787
  • Cathcart K, Pinilla-Ibarz J, Korontsvit T, Schwartz J, Zakhaleva V, Papadopoulos E B, et al. A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia. Blood 2003; 103: 1037–1042
  • Bocchia M, Gentili S, Abruzzese E, Fanelli A, Iuliano F, Tabilio A, et al. Effect of a p210 multipeptide vaccine associated with imatinib or interferon in patients with chronic myeloid leukaemia and persistent residual disease: a multicentre observational trial. Lancet 2005; 365: 657–662
  • Li A, Qiao Y, Liu B, Laska E J, Chakravarthi P, Kulko J M, et al. Combination of imatinib mesylate with autologous leukocyte-derived heat shock protein and chronic myelogenous leukemia. Clin Cancer Res 2005; 11: 4460–4468
  • Gutterman J U. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci USA 1994; 91: 1198–1205
  • Harada H, Taniguchi T, Tanaka N. The role of interferon regulatory factors in the interferon system and cell growth control. Biochimie 1998; 80: 641–650
  • Schmidt M, Nagel S, Proba J, Thiede C, Ritter M, Waring J F, et al. Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias. Blood 1998; 91: 22–29
  • Schmidt M, Hochhaus A, Nitsche A, Hehlmann R, Neubauer A. Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-α. Blood 2001; 97: 3648–3650
  • Hao S X, Ren R. Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder. Mol Cell Biol 2000; 20: 1149–1161
  • Holtschke T, Lohler J, Kanno Y, Fehr T, Giese N, Rosenbauer F, et al. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 1996; 87: 307–317
  • Tsujimura H, Tamura T, Ozato K. Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells. J Immunol 2003; 170: 1131–1135
  • Silver R T, Woolf S H, Hehlmann R, Appelbaum F R, Anderson J, Bennett C, et al. An evidence-based analysis of the effect of busulfan, hydroxyurea, interferon and allogeneic bone marrow transplantation in treating the chronic phase of chronic myeloid leukemia: developed for the American Society of Hematology. Blood 1999; 94: 1517–1536
  • Bonifazi F, de Vivo A, Rosti G, Guilhot F, Guilhot J, Trabacchi E, et al. Chronic myeloid leukemia and interferon-α: a study of complete cytogenetic responders. Blood 2001; 98: 3074–3081
  • Baccarani M, Rosti G, de Vivo A, Bonifazi F, Russo D, Martinelli G, et al. A randomized study of interferon-alpha versus interferon-alpha and low-dose arabinosyl cytosine in chronic myeloid leukemia. Blood 2002; 99: 1527–1535
  • Guilhot F, Chastang C, Michallet M, Guerci A, Harousseau J L, Maloisel F, et al. Interferon alfa-2B combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group. N Engl J Med 1997; 337: 223–229
  • O'Brien S G, Guilhot F, Larson R A, Gathmann I, Baccarani M, Cervantes F, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. New Engl J Med 2003; 348: 994–1004
  • Roy L, Guilhot J, Krahnke T, Guerci-Bresler A, Druker B J, Larson R A, et al. Survival advantage from imatinib compared with the combination interferon-alpha plus cytarabine in chronic-phase chronic myelogenous leukemia: historical comparison between two phase 3 trials. Blood 2006; 108: 1478–1484
  • Hochhaus A, Kreil S, Corbin A S, La Rosee P, Muller M C, Lahaye T, et al. Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia 2002; 16: 2190–2196
  • Lucy J E, Jorgensen H G, Mountford J C, Holyoake T L. Punish the parent not the progeny. Blood 2005; 105: 1862–1866
  • Sorel N, Bonet M L, Guillier M, Guilhot F, Brizard A, Turhan A G. Evidence of ABL-kinase domain mutations in highly purified primitive stem cell populations of patients with chronic myelogenous leukemia. Biochem Biophys Res 2004; 323: 728–730
  • Lipton J H, Khoroshko N D, Golenkov A K, Abdulkadyrov K M, Nair K M, Raghunadharao D, et al. The Pegasys CML Study Group. Two-year survival data from a randomized study of peginterferon alfa-2a(40KD) vs interferon alfa-2a in patients with chronic phase chronic myelogenous leukemia. Blood 2003; 102(Suppl 1)3363a
  • Baccarani M, Martinelli G, Rosti G, Trabacchi E, Testoni N, Bassi S, et al. Imatinib an pegylated human recombinant interferon-α2b in early chronic-phase chronic myeloid leukemia. Blood 2004; 104: 4245–4251
  • Berger U, Hochhaus A, Pfirrmann M, Schoch C, Reiter A, Ehninger G, et al. Concept, feasibility and results of the randomized comparison of imatinib combination therapies for chronic myeloid leukemia: the german CML-study IV. Blood 2005; 106(Suppl 1)1083a
  • Guerci A, Nicolini F, Maloisel F, Corm S, Legros L, Rigal-Huguet F, et al. Randomized comparison of imatinib with imatinib combination therapies in newly diagnosed chronic myelogenous leukaemia patients in chronic phase: design and first interim analysis of a phase III trial from the French CML group. Blood 2005; 106(Suppl 1)168a

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.