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Original Articles: Clinical

Treatment of patients with multiple myeloma complicated by renal failure with bortezomib-based regimens

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Pages 890-895 | Received 06 Nov 2007, Accepted 18 Jan 2008, Published online: 01 Jul 2009

References

  • Alexanian R, Barlogie B, Dixon D. Renal failure in multiple myeloma. Pathogenesis and prognostic implications. Arch Intern Med 1990; 150: 1693–1695
  • Bladé J, Fernández-Llama P, Bosch F, Montolíu J, Lens X M, Montoto S, et al. Renal failure in multiple myeloma: presenting features and predictors of outcome in 94 patients from a single institution. Arch Intern Med 1998; 158: 1889–1893
  • Kyle R A, Gertz M A, Witzig T E, Lust J A, Lacy M Q, Dispenzieri A, et al. Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin Proc 2003; 78: 21–33
  • Bladé J, Fernández-Llama P, Bosch F, Montolíu J, Lens X M, Montoto S, et al. Renal failure in multiple myeloma: presenting features and predictors of outcome in 94 patients from a single institution. Arch Intern Med 1998; 158: 1889–1893
  • Knudsen L M, Hippe E, Hjorth M, Holmberg E, Westin J. Renal function in newly diagnosed multiple myeloma – a demographic study of 1353 patients. The Nordic Myeloma Study Group. Eur J Haematol 1994; 53: 207–212
  • Knudsen L M, Hjorth M, Hippe E. Renal failure in multiple myeloma: reversibility and impact on the prognosis. Nordic Myeloma Study Group. Eur J Haematol 2000; 65: 175–181
  • Sakhuja V, Jha V, Varma S, Joshi K, Gupta K L, Sud K, et al. Renal involvement in multiple myeloma: a 10-year study. Ren Fail 2000; 22: 465–477
  • Richardson P G, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348: 2609–2617
  • Jagannath S, Barlogie B, Berenson J, Siegel D, Irwin D, Richardson P G, et al. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 2004; 127: 165–172
  • Richardson P G, Sonneveld P, Schuster M W, Irwin D, Stadtmauer E A, Facon T, et al. Assessment of Proteasome Inhibition for Extending Remissions (APEX) investigators. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005; 352: 2487–2498
  • Orlowski R Z, Voorhees P M, Garcia R A, Hall M D, Kudrik F J, Allred T, et al. Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 2005; 105: 3058–3065
  • Terpos E, Anagnostopoulos A, Heath D, Kastritis E, Christoulas D, Anagnostopoulos N, et al. The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide (VMDT) is an effective regimen for relapsed/refractory myeloma and reduces serum levels of dickkopf-1, RANKL, MIP-1α and angiogenic cytokines. Blood (suppl.) 2006; 108, Abstract 3541
  • Palumbo A, Ambrosini M T, Benevolo G, Pregno P, Pescosta N, Callea V, et al. Italian multiple myeloma network, Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA). Bortezomib, melphalan, prednisone, and thalidomide for relapsed multiple myeloma. Blood 2007; 109: 2767–2772
  • Mateos M V, Hernández J M, Hernández M T, Gutiérrez N C, Palomera L, Fuertes M, et al. Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase1/2study. Blood 2006; 108: 2165–2172
  • Harousseau J L, Attal M, Leleu X, Troncy J, Pegourie B, Stoppa A M, et al. Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of an IFM phase II study. Haematologica 2006; 91: 1498–1505
  • Oakervee H E, Popat R, Curry N, Smith P, Morris C, Drake M, et al. PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br J Haematol 2005; 129: 755–762
  • Bladé J, Samson D, Reece D, Apperley J, Björkstrand B, Gahrton G, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol 1998; 102: 1115–1123
  • Jagannath S, Barlogie B, Berenson J R, Singhal S, Alexanian R, Srkalovic G, et al. SUMMIT/CREST Investigators. Bortezomib in recurrent and/or refractory multiple myeloma. Initial clinical experience in patients with impared renal function. Cancer 2005; 103(6)1195–1200
  • Chanan-Khan A A, Kaufman J L, Mehta J, Richardson P G, Miller K C, Lonial S, et al. Activity and safety of bortezomib in multiple myeloma patients with advanced renal failure: a multicenter retrospective study. Blood 2007; 109(6)2604–2606
  • Onitilo A A, Engle J, Olatosi B, Fagbemi S. Community experience with bortezomib in patients with multiple myeloma. Am J Hematol 2007; 82: 637–639
  • Malani A K, Gupta V, Rangineni R. Bortezomib and dexamethasone in previously untreated multiple myeloma associated with renal failure and reversal of renal failure. Acta Haematol 2006; 116(4)255–258
  • Nozza A, Siracusano L, Armando S. Bortezomib-dexamethasone combination in a patient with refractory multiple myeloma and impaired renal function. Clin Ther 2006; 28(6)953–959
  • Ludwig H, Drach J, Graf H, Lang A, Meran J G. Reversal of acute renal failure by bortezomib-based chemotherapy in patients with multiple myeloma. Haematologica 2007; 92: 1411–1414
  • Mallick N P, Olujohungbe A, Drayson M T. Renal impairment in myeloma: time for a reappraisal?. Nephrol Dial Translant 1998; 13(Suppl 7)30–32

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