393
Views
43
CrossRef citations to date
0
Altmetric
Original Article: Clinical

R-COMP 21 for frail elderly patients with aggressive B-cell non-Hodgkin lymphoma: A pilot study

, , , , , , , , , , & show all
Pages 1081-1086 | Received 21 Nov 2007, Accepted 07 Mar 2008, Published online: 01 Jul 2009

References

  • Brincker H, Pedersen N T, Bendix-Hansen K, Johansen P. Non-Hodgkin's lymphoma subtypes over time in an unselected population of 646 patients: a study of clinico-pathological data and incidence based on a review using the REAL-classification. Leuk Lymphoma 2000; 39: 531–541
  • Devesa S S, Fears T. Non-Hodgkin's lymphoma time trends: United States and international data. Cancer Res 1992; 52: 5432–5440
  • Cartwright R, Brincker H, Carli P M, Clayden D, Coebergh J W, Jack A, et al. The rise in incidence of lymphomas in Europe 1985–1992. Eur J Cancer 1999; 35: 627–633
  • Muller A, Ihorst G, Mertelsmann R, Engelhardt M. Epidemiology of non-Hodgkin's lymphoma (NHL): trends, geographic distribution and etiology. Ann Haematol 1999; 84: 1–12
  • The International Non-Hodgkin's Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med 1993; 329: 987–994
  • The Non-Hodgkin's Lymphoma Classification Project. Effect of age on the characteristics and clinical behavior of non-Hodgkin's lymphoma patients. Ann Oncol 1997; 8: 973–978
  • Bastion Y, Blay J Y, Divine M, Brice P, Bordessoule D, Sebban C. Elderly patients with aggressive non-Hodgkin's lymphoma: disease presentation, response to treatment, and survival-a Groupe d'Etude des Lymphomes de l'Adulte study on 453 patients older than 69 years. J Clin Oncol 1997; 15: 2945–2953
  • Vose J M, Armitage J O, Weisenburger D D, Bierman P J, Sorensen S, Hutchins M. The importance of age in survival of patients treated with chemotherapy for aggressive non-Hodgkin's lymphoma. J Clin Oncol 1988; 6: 1838–1844
  • Fisher R I, Gaynor E R, Dahlberg S, Oken M M, Grogan T M, Mize E M. Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma. N Engl J Med 1993; 328: 1002–1006
  • Gordon L I, Harrington D, Andersen J, Colgan J, Glick J, Neiman R. Comparison of a second-generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkin's lymphoma. N Engl J Med 1992; 327: 1342–1349
  • Jerkeman M, Anderson H, Cavallin-Ståhl E, Dictor M, Hagberg H, Johnson A, et al. CHOP versus MACOP-B in aggressive lymphoma – a Nordic Lymphoma Group randomised trial. Ann Oncol 1999; 10: 1079–1086
  • Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 2002; 346: 235–242
  • Armitage J O, Potter J F. Aggressive chemotherapy for diffuse histiocytic lymphoma in the elderly: increased complications with advancing age. J Am Geriatr Soc 1984; 32: 269–273
  • Sonneveld P, de Ridder M, van der Lelie H, Nieuwenhuis K, Schouten H, Mulder A, et al. Comparison of doxorubicin and mitoxantrone in the treatment of elderly patients with advanced diffuse non-Hodgkin's lymphoma using CHOP versus CNOP chemotherapy. J Clin Oncol 1995; 13: 2530–2539
  • Meyer R, Browman G, Samosh M, Benger A, Bryant-Lukosius D, Wilson W, et al. Randomized phase II comparison of standard CHOP with weekly CHOP in elderly patients with non-Hodgkin's lymphoma. J Clin Oncol 1995; 13: 2386–2393
  • Conley B A, Egorin M J, Whitacre M T, Carter D C, Zuhowski E G, Van Echo D A. Phase I and pharmacokinetic trial of liposome encapsulated doxorubicin. Cancer Chemother Pharmacol 1993; 33: 107–112
  • Cowens J W, Creaven P J, Greco W R, Brenner D E, Tung Y, Ostro M, et al. Initial clinical (Phase I) trial of Myocet (doxorubicin encapsulated in liposomes). Cancer Res 1993; 53: 2796–2802
  • Ostro M J. Liposomes: from the bench to the marketplace—doxorubicin as an example. Liposomes in the Therapy of Infectious Diseases and Cancer, I J Fidler, G Lopez-Berestein. New York, Alan Liss 1989; 155–163
  • Mayer L D, Bally M B, Cullis P R, Wilson S L, Emerman J T. Comparison of free and liposome-encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mammary tumor. Cancer Lett 1990; 53: 183–190
  • Batist G, Ramakrishnan G, Rao C S, Chandrasekharan A, Gutheil J, Guthrie T, et al. Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer. J Clin Oncol 2001; 19: 1444–1454
  • Balducci L, Extermann M. Management of cancer in the older person: a practical approach. Oncologist 2000; 5: 224–237
  • Cheson B D, Horning S J, Coiffier B. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. J Clin Oncol 1999; 17: 1244–1253
  • Fleming T R. One-sample multiple testing procedure for Phase II clinical trials. Biometrics 1982; 38: 143–151
  • Harris N L, Jaffe E S, Stein H. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994; 84: 1361–1392
  • Carbone P P, Kaplan H S, Musshoff K. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res 1971; 31: 1860–1861
  • Levine A M, Tulpule A, Espina B, Sherrod A, Boswell W D, Lieberman R D, et al. Liposome-encapsulated doxorubicin in combination with standard agents (cyclophosphamide, vincristine, prednisone) in patients with newly diagnosed AIDS-related non-Hodgkin's lymphoma: results of therapy and correlates of response. J Clin Oncol 2004; 22: 2662–2670
  • Tulpule A, Espina B M, Berman N, Buchanan L H, Smith D L, Sherrod A, et al. Phase I/II trial of nonpegylated liposomal doxorubicin, cyclophosphamide, vincristine, and prednisone in the treatment of newly diagnosed aggressive non-Hodgkin's lymphoma. Clin Lymphoma Myeloma 2006; 7: 59–64
  • Rigacci L, Mappa S, Nassi L, Alterini R, Carrai V, Bernardi F, Bosi A. Liposome-encapsulated doxorubicin in combination with cyclophosphamide, vincristine, prednisone and rituximab in patients with lymphoma and concurrent cardiac diseases or pre-treated with anthracyclines. Hematol Oncol 2007; 25: 198–203

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.