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Commentary

Splicing the way to leukemia with KIT

Pages 1431-1432 | Published online: 01 Jul 2009

References

  • Yan M, Kanbe E, Peterson L F, Boyapati A, Miao Y, Wang Y, et al. A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Nat Med 2006; 12: 945–949
  • Heinrich M C, Blanke C D, Druker B J, Corless C L. Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 2002; 20: 1692–1703
  • Kim H H, Vijapurkar U, Hellyer N J, Bravo D, Koland J G. Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein. Biochem J 1998; 334(Pt 1)189–195
  • Sette C, Bevilacqua A, Geremia R, Rossi P. Involvement of phospholipase Cγ1 in mouse egg activation induced by a truncated form of the C-kit tyrosine kinase present in spermatozoa. J Cell Biol 1998; 142: 1063–1074

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