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Letters to the Editor

OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients

, , , &
Pages 2222-2223 | Received 06 May 2008, Accepted 03 Jul 2008, Published online: 01 Jul 2009

References

  • Goldman J M. How I treat chronic myeloid leukemia in the imatinib era. Blood 2007; 110: 2828–2837
  • White D L, Saunders V A, Dang P, Engler J, Venables A, Zrim S, et al. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood 2007; 110: 4064–4072
  • Shu Y, Leabman M K, Feng B, Mangravite L M, Huang C C, Stryke D, et al. Evolutionary conservation predicts function of the human organic cation transporter, OCT1. Proc Natl Acad Sci USA 2003; 100: 5902–5907
  • Gabert J, Beillard E, van der Velden V HJ, Bi W, Grimwade D, Pallisgaard N, et al. Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – a Europe against cancer program. Leukemia 2003; 17: 2318–2357

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