References
- Moalli P A, Pillay S, Weiner D, Leikin R, Rosen S T. A mechanism of resistance to glucocorticoids in multiple myeloma: transient expression of a truncated glucocorticoid receptor mRNA. Blood 1992; 79: 213–222
- Ma S, Zhan F, Ma C, Tessel M, Zhang L, Rajkumar S V, et al. Glucocorticoid receptor expression correlates with clinical outcome in myeloma patients treated with glucocorticoid-containing regimens. Blood 2008; 112, abstract #1700
- Weigel N L, Moore N L. Steroid receptor phosphorylation: a key modulator of multiple functions. Mol Endocrinol 2007; 21: 2311–2319
- Ismaili N, Garabedian M J. Modulation of glucocorticoid receptor function via phosphorylation. Ann N Y Acad Sci 2004; 1024: 86–101
- Miller A L, Webb M S, Copik A J, Wang Y, Johnson B H, Kumar R, et al. Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211. Mol Endocrinol 2005; 19: 1569–1583
- Chen W, Dang T, Blind R D, Wang Z, Cavasotto C N, Hittelman A B, et al. Glucocorticoid receptor phosphorylation differentially affects target gene expression. Mol Endocrinol 2008; 22: 1754–1766
- Carter B Z, Mak D H, Schober W D, McQueen T, Harris D, Estrov Z, et al. Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood 2006; 108: 630–637
- Yang M, Huang J, Pan H Z, Jin J. Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3K/Akt/NF-kappaB pathways in human multiple myeloma cells. Int J Mol Med 2008; 22: 489–496
- Yang M, Shen J, Huang J, Du H, Ma Q, Jin J. IL-6 independent expression of glucocorticoid receptor is upregulated by triptolide in multiple myeloma. Leuk Lymphoma 2009; 50, in press