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Letters to the Editor

Impact of metformin on the progression of MGUS to multiple myeloma

, , &
Pages 1265-1267 | Received 03 May 2016, Accepted 08 Sep 2016, Published online: 05 Oct 2016

References

  • Weiss BM, Abadie J, Verma P, et al. A monoclonal gammopathy precedes multiple myeloma in most patients. Blood. 2009;113:5418–5422.
  • Landgren O, Kyle RA, Pfeiffer RM, et al. Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study. Blood. 2009;113:5412–5417.
  • Kyle RA, Therneau TM, Rajkumar SV, et al. Prevalence of monoclonal gammopathy of undetermined significance. N Engl J Med. 2006;354:1362–1369.
  • Röllig C, Knop S, Bornhäuser M. Multiple myeloma. Lancet. 2015;385:2197–2208.
  • Kyle RA, Therneau TM, Rajkumar SV, et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med. 2002;346:564–569.
  • Rajkumar SV. Risk of progression in MGUS. Lancet Haematol. 2014;2:e6–e7.
  • Decensi A, Puntoni M, Goodwin P, et al. Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis. Cancer Prev Res. 2010;3:1451–1461.
  • Pollak MN. Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov. 2012;2:778–790.
  • Ferlin M, Noraz N, Hertogh C, et al. Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway. Br J Haematol. 2000;111:626–634.
  • Brown LM, Gridley G, Pottern LM, et al. Diet and nutrition as risk factors for multiple myeloma among blacks and whites in the United States. Cancer Causes Control. 2001;12:117–125.
  • Chang SH, Luo S, O’Brian KK, et al. Association between metformin use and progression of monoclonal gammopathy of undetermined significance to multiple myeloma in US veterans with diabetes mellitus: a population-based retrospective cohort study. Lancet Haematol. 2015;2:e30–e36.
  • Lubin JH, Gail MH. Biased selection of controls for case-control analyses of cohort studies. Biometrics. 1984;40:63–75.
  • Suissa S, Azoulay L. Metformin and the risk of cancer: time-related biases in observational studies. Diabetes Care. 2012;35:2665–2673.
  • Haynes K, Forde KA, Schinnar R, et al. Cancer incidence in The Health Improvement Network. Pharmacoepidemiol Drug Saf. 2009;18:730–736.
  • Cea Soriano L, Soriano-Gabarro M, Garcia Rodriguez LA. Validity and completeness of colorectal cancer diagnoses in a primary care database in the United Kingdom. Pharmacoepidemiol Drug Saf. 2016;25:385–391.
  • LeGrand J, Park ES, Wang H, et al. Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. Blood. 2012;119:1018–1028.
  • Dalva-Aydemir S, Bajpai R, Martinez M, et al. Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. Clin Cancer Res. 2015;21:1161–1171.

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