References
- Drayson M, Begum G, Basu S, et al. Effects of paraprotein heavy and light chain types and free light chain load on survival in myeloma: an analysis of patients receiving conventional-dose chemotherapy in Medical Research Council UK multiple myeloma trials. Blood. 2006;108:2013–2019.
- Durie BG, Harousseau JL, Miguel JS, et al. International uniform response criteria for multiple myeloma. Leukemia. 2006;20:1467–1473.
- Dimopoulos M, Kyle R, Fermand JP, et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3. Blood. 2011;117:4701–4705.
- Kyle RA, Rajkumar SV. Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma. Leukemia. 2009;23:3–9.
- Vaerman JP, Langendries A, Vander Maelen C. Homogenous IgA monomers, dimers, trimers and tetramers from the same IgA myeloma serum. Immunol Investig. 1995;24:631–641.
- Keren DF. Protein electrophoresis in clinical diagnosis. Arnold (Hodder Headline); 2003. Chapter 2, Techniques for protein electrophoresis; p. 25.
- Murray DL, Ryu E, Snyder MR, et al. Quantitation of serum monoclonal proteins: relationship between agarose gel electrophoresis and immunonephelometry. Clin Chem. 2009;55:1523–1529.
- Katzmann JA, Snyder MR, Rajkumar SV, et al. Long-term biological variation of serum protein electrophoresis M-spike, urine M-spike, and monoclonal serum free light chain quantification: implications for monitoring monoclonal gammopathies. Clin Chem. 2011;57:1687–1692.
- Bradwell AR, Harding SJ, Fourrier NJ, et al. Assessment of monoclonal gammopathies by nephelometric measurement of individual immunoglobulin kappa/lambda ratios. Clin Chem. 2009;55:1646–1655.
- Bradwell A, Harding S, Fourrier N, et al. Prognostic utility of intact immunoglobulin Ig’kappa/Ig’lambda ratios in multiple myeloma patients. Leukemia. 2013;27:202–207.
- Bhutani M, Costello R, Korde N, et al. Serum heavy-light chains (HLC) and free light chains (FLC) as predictors for early CR in newly diagnosed myeloma patients treated with carfilzomib, lenalidomide, and dexamethasone (CRd). Blood. 2013;122:762.
- Donato LJ, Zeldenrust SR, Murray DL, et al. A 71-year-old woman with multiple myeloma status after stem cell transplantation. Clin Chem. 2011;57:1645–1648.
- Ludwig H, Milosavljevic D, Zojer N, et al. Immunoglobulin heavy/light chain ratios improve paraprotein detection and monitoring, identify residual disease and correlate with survival in multiple myeloma patients. Leukemia. 2013;27:213–219.
- Katzmann JA, Willrich MA, Kohlhagen MC, et al. Monitoring IgA multiple myeloma: immunoglobulin heavy/light chain assays. Clin Chem. 2015;61:360–367.
- Leleu X, Attal M, Arnulf B, et al. Pomalidomide plus low-dose dexamethasone is active and well tolerated in bortezomib and lenalidomide-refractory multiple myeloma: Intergroupe Francophone du Myélome 2009-02. Blood. 2013;121:1968–1975.
- Leleu X, Karlin L, Macro M, et al. Pomalidomide plus low-dose dexamethasone in multiple myeloma with deletion 17p and/or translocation (4;14): IFM 2010-02 trial results. Blood. 2015;125:1411–1417.
- Rajkumar SV, Harousseau JL, Durie B, et al. Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1. Blood. 2011;117:4691–4695.
- Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174.
- Akaike H. Likelihood of model and information criteria. J Econom. 1981;16:3–14.
- Harrell FE Jr, Califf RM, Pryor DB, et al. Evaluating the yield of medical tests. Jama. 1982;247:2543–2546.
- Dispenzieri A, Kyle RA. Multiple myeloma: clinical features and indications for therapy. Best Pract Res Clin Haematol. 2005;18:553–568.
- Waldmann TA, Strober W. Metabolism of immunoglobulins. Prog Allergy. 1969;13:1–110.
- Kim J, Hayton WL, Robinson JM, et al. Kinetics of FcRn-mediated recycling of IgG and albumin in human: pathophysiology and therapeutic implications using a simplified mechanism-based model. Clin Immunol (Orlando, Fla). 2007;122:146–155.
- Lakomy D, Lemaire-Ewing S, Denimal D, et al. [Evaluation of the new Hevylite IgA assay for the diagnosis and follow-up of monoclonal gammopathies]. Ann Biol Clin. 2013;71:157–163.
- Ludwig H, Milosavljevic D, Berlanga O, et al. Suppression of the noninvolved pair of the myeloma isotype correlates with poor survival in newly diagnosed and relapsed/refractory patients with myeloma. Am J Hematol. 2016;91:295–301.
- Ludwig H, Slavka G, Hübl W, et al. Usage of HLC-Ratio, FLC-Ratio, Ife, pbmc infiltration and isotype suppression at best response reveals isotype suppression as most powerful parameter for identification of multiple myeloma patients with long survival. Blood. 2012;120:1817.
- Drayson MT, Berlanga O, Plant T, Newnham NJ, Young P, Harding S. Immunoglobulin heavy/light chain measurements during monitoring provide prognostic information of relapse after therapy in myeloma patients. Blood. 2012;120:3964.