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Original Articles: Clinical

Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia

, , , , , , , & show all
Pages 837-843 | Received 18 Apr 2017, Accepted 19 Jul 2017, Published online: 07 Aug 2017

References

  • McCune JS, Holmberg LA. Busulfan in hematopoietic stem cell transplant setting. Expert Opin Drug Metab Toxicol. 2009;5:957–969.
  • Santos GW, Tutschka PJ, Brookmeyer R, et al. Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. N Engl J Med. 1983;309:1347–1353.
  • Bacigalupo A. Hematopoietic stem cell transplants after reduced intensity conditioning regime (RI-HSCT): report of a workshop of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant. 2000;25:803–805.
  • Carella AM, Champlin R, Slavin S, et al. Mini-allografts: ongoing trials in humans. Bone Marrow Transplant. 2000;25:345–350.
  • Wahid SFA, Ismail NA, Mohd-Idris MR, et al. Comparison of reduced-intensity and myeloablative conditioning regimens for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia and acute lymphoblastic leukemia: a meta-analysis. Stem Cells Dev. 2014;23:2535–2552.
  • Shimoni A, Hardan I, Shem-Tov N, et al. Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: the role of dose intensity. Leukemia. 2006;20:322–328.
  • Scott BL, Pasquini MC, Logan BR, et al. Myeloablative versus reduced-intensity hematopoietic cell transplantation for acute myeloid leukemia and myelodysplastic syndromes. J Clin Oncol. 2017;35:1154–1161.
  • Baron F, Labopin M, Peniket A, et al. Reduced-intensity condition in myeloablative versus reduced-intensity hematopoietic cell transplantation for acute myeloid leukemia and myelodysplastic syndromesg with fludarabine and busulfan versus fludarabine and melphalan for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. Cancer. 2015;121:1048–1055.
  • Copelan EA, Hamilton BK, Avalos B, et al. Better leukemia-free and overall survival in AML in first remission following cyclophosphamide in combination with busulfan compared with TBI. Blood. 2013;122:3863–3870.
  • Shimoni A, Hardan I, Shem-Tov N, et al. Comparison between two fludarabine-based reduced-intensity conditioning regimens before allogeneic hematopoietic stem-cell transplantation: fludarabine/melphalan is associated with higher incidence of acute graft-versus-host disease and non-relapse mortality and lower incidence of relapse than fludarabine/busulfan. Leukemia. 2007;21:2109–2116.
  • Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496–509.
  • Therneau T. A package for survival analysis in S version 2.38. 2015.
  • Gray RJ. cmprsk: Subdistribution analysis of competing risks, 2014.
  • Nagler A, Labopin M, Shimoni A, et al. Intravenous busulfan-based conditioning prior to allogeneic stem cell transplantation in adults patients with AML – an ALWP-EBMT survey. Blood. 2007;110:1995.

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