Prolonged hospitalization, primary refractory disease, performance status and age are prognostic factors for survival in patients with diffuse large B-cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation

References

• Coiffier B, Thieblemont C, Van Den Neste E, et al. Long-term outcome of patients in the LNH-98. 5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d’ Etudes des Lymphomes de l’ Adulte. Blood. 2010;116:1–8.
   PubMed Web of Science ®Google Scholar
• Pfreundschuh M, Kuhnt E, Trümper L, et al. CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group. Lancet Oncol. 2011;12:1013–1022.
   PubMed Web of Science ®Google Scholar
• Sehn LH, Berry B, Chhanabhai M, et al. The revised International Prognostic Index (R-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP. Blood. 2007;109:1857–1861.
   PubMed Web of Science ®Google Scholar
• Philip T, Guglielmi C, Hagenbeek A, et al. Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin’s lymphoma. N Engl J Med. 1995;333:1540–1545.
   PubMed Web of Science ®Google Scholar
• Armitage JO, Longo DL. Is watch and wait still acceptable for patients with low grade follicular lymphoma? Blood. 2016;127:2804–2809.
   PubMed Web of Science ®Google Scholar
• Montoto S. Treatment of patients with transformed lymphoma. Hematology Am Soc Hematol Educ Program. 2015;2015:625–630.
   PubMedGoogle Scholar
• Kuruvilla J, Macdonald D. a, Kouroukis CT, et al. Salvage chemotherapy and autologous stem cell transplantation for transformed indolent lymphoma: a subset analysis of NCIC CTG LY12. Blood. 2015;126:733–739.
   PubMed Web of Science ®Google Scholar
• Vellenga E, Van Putten WLJ, Van Veer MB, et al. Rituximab improves the treatment results of DHAP-VIM-DHAP and ASCT in relapsed/progressive aggressive CD20 + NHL: a prospective. Blood. 2008;111:537–543.
   PubMed Web of Science ®Google Scholar
• Gisselbrecht C, Glass B, Mounier N, et al. Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era. J Clin Oncol. 2010;28:4184–4190.
   PubMed Web of Science ®Google Scholar
• Majhail NS, Ness KK, Burns LJ, et al. Late effects in survivors of Hodgkin and non-Hodgkin lymphoma treated with autologous hematopoietic cell transplantation: a report from the bone marrow transplant survivor study. Biol Blood Marrow Transplant. 2007;13:1153–1159.
   PubMed Web of Science ®Google Scholar
• Wildes TM, Augustin KM, Sempek D, et al. Comorbidities, not age, impact outcomes in autologous stem cell transplant for relapsed non-Hodgkin lymphoma. Biol Blood Marrow Transplant. 2008;14:840–846.
   PubMed Web of Science ®Google Scholar
• Arboe B, El-Galaly TC, Clausen MR, et al. The Danish National Lymphoma Registry: coverage and data quality. PLoS One. 2016;11:e0157999.
   PubMed Web of Science ®Google Scholar
• Pedersen CB. The Danish Civil Registration System. Scand J Public Health. 2011;39:22–25.
   PubMed Web of Science ®Google Scholar
• Schmidt M, Pedersen L, Sørensen HT. The Danish Civil Registration System as a tool in epidemiology. Eur J Epidemiol. 2014;29:541–549.
   PubMed Web of Science ®Google Scholar
• Kragholm K, Wissenberg M, Mortensen RN, et al. Return to work in out-of-hospital cardiac arrest survivors: a nationwide register-based follow-up study. Circulation. 2015;131:1682–1690.
   PubMed Web of Science ®Google Scholar
• Baadsgaard M, Quitzau J. Danish registers on personal income and transfer payments. Scand J Public Health. 2011;39:103–105.
   PubMed Web of Science ®Google Scholar
• Hjollund NH, Larsen FB, Andersen JH. Register-based follow-up of social benefits and other transfer payments: accuracy and degree of completeness in a Danish interdepartmental administrative database compared with a population-based survey. Scand J Public Health. 2007;35:497–502.
   PubMed Web of Science ®Google Scholar
• Lund T, Kivimäki M, Christensen KB, et al. Socio-economic differences in the association between sickness absence and mortality: the prospective DREAM study of Danish private sector employees. Occup Environ Med. 2009;66:150–153.
   PubMed Web of Science ®Google Scholar
• Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health. 2011;39:30–33.
   PubMed Web of Science ®Google Scholar
• Schmidt M, Schmidt S, Sandegaard J, et al. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449–490.
   PubMed Web of Science ®Google Scholar
• Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–383.
   PubMedGoogle Scholar
• Therneau TM. A package for survival snalysis in R [Internet]. 2015. Available from: https://cran.r-project.org/package=survival.
   Google Scholar
• Robinson SP, Boumendil A, Finel H, et al. Autologous stem cell transplantation for relapsed/refractory diffuse large B-cell lymphoma: efficacy in the rituximab era and comparison to first allogeneic transplants. A report from the EBMT Lymphoma Working Party. Bone Marrow Transplant. 2016;51:365–371.
   PubMed Web of Science ®Google Scholar
• Piccirillo JF, Vlahiotis A, Barrett LB, et al. The changing prevalence of comorbidity across the age spectrum. Crit Rev Oncol Hematol. 2008;67:124–132.
   PubMed Web of Science ®Google Scholar
• Graf SA, Vaughn JE, Chauncey TR, et al. Comorbidities, alcohol use disorder, and age predict outcomes after autologous hematopoietic cell transplantation for lymphoma. Biol Blood Marrow Transplant. 2016;22:1582–1587.
   PubMed Web of Science ®Google Scholar
• Lahoud OB, Sauter CS, Hamlin PA, et al. High-dose chemotherapy and autologous stem cell transplant in older patients with lymphoma. Curr Oncol Rep. 2015;17:42.
   PubMed Web of Science ®Google Scholar
• Carli F, Zavorsky GS. Optimizing functional exercise capacity in the elderly surgical population. Curr Opin Clin Nutr Metab Care. 2005;8:23–32.
   PubMed Web of Science ®Google Scholar
• Santa Mina D, Scheede-Bergdahl C, Gillis C, et al. Optimization of surgical outcomes with prehabilitation. Appl Physiol Nutr Metab. 2015;969:966–969.
   Google Scholar
• Carli F, Scheede-Bergdahl C. Prehabilitation to enhance perioperative care. Anesthesiol Clin. 2015;33:17–33.
   PubMedGoogle Scholar
• Gillis C, Li C, Lee L, et al. Prehabilitation versus rehabilitation. Anesthesiology. 2014;121:937–947.
   PubMed Web of Science ®Google Scholar
• Bartels FR, Smith NS, Gørløv JS, et al. Optimized patient-trajectory for patients undergoing treatment with high-dose chemotherapy and autologous stem cell transplantation. Acta Oncol. 2015;54:750–758.
   PubMed Web of Science ®Google Scholar
• Crump M, Kuruvilla J, Couban S, et al. Randomized comparison of gemcitabine, dexamethasone, and cisplatin versus dexamethasone, cytarabine, and cisplatin chemotherapy before autologous stem-cell transplantation for relapsed and refractory aggressive lymphomas: NCIC-CTG LY.12. J Clin Oncol. 2014;32:3490–3496.
   PubMed Web of Science ®Google Scholar
• Tao L, Foran JM, Clarke C. a, et al. Socioeconomic disparities in mortality after diffuse large B-cell lymphoma in the modern treatment era. Blood. 2014;123:3553–3562.
   PubMed Web of Science ®Google Scholar
• Olsen MH, Bøje CR, Kjaer TK, et al. Socioeconomic position and stage at diagnosis of head and neck cancer - a nationwide study from DAHANCA. Acta Oncol. 2015;54:759–766.
   PubMed Web of Science ®Google Scholar
• Frederiksen BL, Brown PDN, Dalton SO, et al. Socioeconomic inequalities in prognostic markers of non-Hodgkin lymphoma: analysis of a national clinical database. Eur J Cancer. 2011;47:910–917.
   PubMed Web of Science ®Google Scholar
• Frederiksen BL, Dalton SO, Osler M, et al. Socioeconomic position, treatment, and survival of non-Hodgkin lymphoma in Denmark - a nationwide study. Br J Cancer. 2012;106:988–995.
   PubMed Web of Science ®Google Scholar
• Galobardes B, Shaw M, Lawlor DA, et al. Indicators of socioeconomic position (part 1). J Epidemiol Community Health. 2006;60:7–12.
   PubMed Web of Science ®Google Scholar
• Galobardes B, Shaw M, Lawlor D. a, et al. Indicators of socioeconomic position (part 2). J Epidemiol Community Health. 2006;60:95–101.
   PubMed Web of Science ®Google Scholar
• Hong S, Rybicki L, Abounader DM, et al. Association of socioeconomic status with autologous hematopoietic cell transplantation outcomes for lymphoma. Bone Marrow Transplant. 2016;51:1191–1196.
   PubMed Web of Science ®Google Scholar