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Leukemia & Lymphoma Volume 59, 2018 - Issue 8
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Original Article: Clinical

Outcomes of DA-EPOCH-R induction plus autologous transplant consolidation for double hit lymphoma

Andy I. ChenCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; Correspondence[email protected]
,
Jessica T. LeonardCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA;
,
Craig Y. OkadaCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA;
,
Nathan D. GayCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA;
,
Kari ChanskyCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; ;Cancer Research and Biostatistics, Seattle, WA, USA;
,
Guang FanCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; ;Department of Pathology, Oregon Health & Science University, Portland, OR, USA
,
Jennifer B. DunlapCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; ;Department of Pathology, Oregon Health & Science University, Portland, OR, USA
,
Philipp W. RaessCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; ;Department of Pathology, Oregon Health & Science University, Portland, OR, USAORCID Iconhttp://orcid.org/0000-0002-6841-4993
ORCID Icon,
Rita M. BrazielCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA; ;Department of Pathology, Oregon Health & Science University, Portland, OR, USA
,
Alex StentzCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA;
&
Richard T. MaziarzCenter for Hematologic Malignancies, Oregon Health & Science University, Portland, OR, USA;
show all
Pages 1884-1889 | Received 11 Jun 2017, Accepted 12 Nov 2017, Published online: 03 Dec 2017

References

  • Sarkozy C, Traverse-Glehen A, Coiffier B. Double-hit and double-protein-expression lymphomas: aggressive and refractory lymphomas. Lancet Oncol. 2015;16:e555–e567.
  • Sesques P, Johnson NA. Approach to the diagnosis and treatment of high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements. Blood. 2017;129:280–288.
  • Aukema SM, Siebert R, Schuuring E, et al. Double-hit B-cell lymphomas. Blood. 2011;117:2319–2331.
  • Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127:2375–2390.
  • Johnson NA, Slack GW, Savage KJ, et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol. 2012;30:3452–3459.
  • Petrich AM, Gandhi M, Jovanovic B, et al. Impact of induction regimen and stem cell transplantation on outcomes in double-hit lymphoma: a multicenter retrospective analysis. Blood. 2014;124:2354–2361.
  • Stiff PJ, Unger JM, Cook JR, et al. Autologous transplantation as consolidation for aggressive non-Hodgkin’s lymphoma. N Engl J Med. 2013;369:1681–1690.
  • Dunleavy K, Pittaluga S, Shovlin M, et al. Low-intensity therapy in adults with Burkitt’s lymphoma. N Engl J Med. 2013;369:1915–1925.
  • Juweid ME, Stroobants S, Hoekstra OS, et al. Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma. J Clin Oncol. 2007;25:571–578.
  • Landsburg DJ, Falkiewicz MK, Maly J, et al. Outcomes of patients with double-hit lymphoma who achieve first complete remission. J Clin Oncol. 2017;35:2260–2267.
  • Sun H, Savage KJ, Karsan A, et al. Outcome of patients with non-Hodgkin lymphomas with concurrent MYC and BCL2 rearrangements treated with CODOX-M/IVAC with Rituximab followed by hematopoietic stem cell transplantation. Clin Lymphoma Myeloma Leuk. 2015;15:341–348.
  • Oki Y, Noorani M, Lin P, et al. Double hit lymphoma: the MD Anderson Cancer Center clinical experience. Br J Haematol. 2014;166:891–901.
  • Dunleavy K, Fanale MA, LaCasce A, et al. Preliminary report of a multicenter prospective phase II study of DA-EPOCH-R in MYC-rearranged aggressive B-cell lymphoma. American Society of Hematology. Blood. 2014;124:395.
  • Cuccuini W, Briere J, Mounier N, et al. MYC + diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation. Blood. 2012;119:4619–4624.
  • Herrera AF, Mei M, Low L, et al. Relapsed or refractory double-expressor and double-hit lymphomas have inferior progression-free survival after autologous stem-cell transplantation. J Clin Oncol. 2017;35:24–31.

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