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Original Article: Clinical

Thromboembolic complications following aminocaproic acid use in patients with hematologic malignancies

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Pages 2377-2382 | Received 10 Sep 2017, Accepted 21 Jan 2018, Published online: 09 Feb 2018

References

  • Amicar® [FDA label] [Internet]. [cited 2016 Sept 5]. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/15197scm036,scf037,scp038,scm039_amicar_lbl.pdf
  • Bartholomew JR, Salgia R, Bell WR. Control of bleeding in patients with immune and nonimmune thrombocytopenia with aminocaproic acid. Arch Intern Med. 1989;149:1959–1961.
  • Gardner FH, Helmer RE. Aminocaproic acid use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. JAMA. 1980;243:35–37.
  • Schiffer CA, Anderson KC, Bennett CL, et al. Platelet transfusion for patients with cancer: clinical practice guidelines of the American Society of Clinical Oncology. JCO. 2001;19:1519–1538.
  • Benson K, Fields K, Hiemenz J, et al. The platelet-refractory bone marrow transplant patient: prophylaxis and treatment of bleeding. Semin Oncol. 1993;20(5 suppl 6):102–109.
  • Antun AG, Gleason S, Arellano M, et al. Epsilon aminocaproic acid prevents bleeding in severely thrombocytopenic patients with hematological malignancies. Cancer. 2013;119:3784–3787.
  • Marshall A, Li A, Drucker A, et al. Aminocaproic acid use in hospitalized patients with hematological malignancy: a case series. Hematol Oncol. 2016;34:147–153.
  • Estcourt LJ, Desborough M, et al. Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders. Cochrane Database Syst Rev. 2016;153:CD009733.
  • Dalmau A, Sabate A, Acosta F, et al. Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation. Anesth Analg. 2000;91:29–34.
  • Gerstein NS, Brierley JK, et al. Antifibrinolytic agents in cardiac and noncardiac surgery: a comprehensive overview and update. J Cardiothorac Vasc Anesth. 2017;31:2183–2205.
  • Henry DA, Moxey AJ, Carless PA, et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev. 2011. DOI:10.1002/14651858.CD001886.pub4
  • Kopolovic I, Lee AYY, Wu C. Management and outcomes of cancer-associated venous thromboembolism in patients with concomitant thrombocytopenia: a retrospective cohort study. Ann Hematol. 2015;94:329–336.
  • Kalmadi S, Tiu R, Lowe C, et al. Epsilon aminocaproic acid reduces transfusion requirements in patients with thrombocytopenic hemorrhage. Cancer. 2006;107:136–140.

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