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Leukemia & Lymphoma Volume 59, 2018 - Issue 10
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Letter to the Editor

Deep spontaneous molecular remission in a patient with congenital acute myeloid leukemia expressing a novel MOZ-p300 fusion transcript

Yasuhiro IkawaDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; ORCID Iconhttp://orcid.org/0000-0001-7204-1766
ORCID Icon,
Ryosei NishimuraDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; Correspondence[email protected]
,
Hideaki MaebaDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Toshihiro FujikiDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; ORCID Iconhttp://orcid.org/0000-0002-3526-4618
ORCID Icon,
Rie KurodaDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Kazuhiro NoguchiDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Masaki FukudaDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Shintaro MaseDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Raita ArakiDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Yusuke MitaniDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
,
Tomohiko SatoDepartment of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Aomori Prefecture, Japan;
,
Kiminori TeruiDepartment of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Aomori Prefecture, Japan;
,
Etsurou ItoDepartment of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Aomori Prefecture, Japan;
,
Issay KitabayashiDivision of Hematological Malignancy, National Cancer Center Research Institute, Tokyo, Japan
&
Akihiro YachieDepartment of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
show all
Pages 2497-2499 | Received 30 Oct 2017, Accepted 21 Jan 2018, Published online: 12 Feb 2018

References

  • Coenen EA, Zwaan CM, Reinhardt D, et al. Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group. Blood. 2013;122:2704–2713.
  • Camus V, Etancelin P, Jardin F, et al. Spontaneous remission in three cases of AML M5 with NPM1 mutation. Clin Case Rep. 2015;3:955–959.
  • Muller CI, Trepel M, Kunzmann R, et al. Hematologic and molecular spontaneous remission following sepsis in acute monoblastic leukemia with translocation (9;11): a case report and review of the literature. Eur J Haematol. 2004;73:62–66.
  • Haferlach T, Kohlmann A, Klein HU, et al. AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features. Leukemia. 2009;23:934–943.
  • Troke PJ, Kindle KB, Collins HM, et al. MOZ fusion proteins in acute myeloid leukaemia. Biochem Soc Symp. 2006;(73):23–39.
  • Esteyries S, Perot C, Adelaide J, et al. NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia. Leukemia. 2008;22:663–665.
  • Kitabayashi I, Aikawa Y, Yokoyama A, et al. Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation. Leukemia. 2001;15:89–94.
  • Chaffanet M, Gressin L, Preudhomme C, et al. MOZ is fused to p300 in an acute monocytic leukemia with t(8;22). Genes Chromosom Cancer. 2000;28:138–144.
  • Iyer NG, Ozdag H, Caldas C. p300/CBP and cancer. Oncogene. 2004;23:4225–4231.
  • Hudecova I. Digital PCR analysis of circulating nucleic acids. Clin Biochem. 2015;48:948–956.

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