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Leukemia & Lymphoma Volume 59, 2018 - Issue 12
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Letter to the Editor

Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia

Poojitha N. OjamiesInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-4921-7134View further author information
ORCID Icon,
Mika KontroHematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; View further author information
,
Henrik EdgrenMediSapiens Ltd, Helsinki, Finland; View further author information
,
Pekka EllonenInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; View further author information
,
Caroline HeckmanInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; View further author information
,
Kimmo PorkkaHematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; View further author information
,
Maija WolfInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; View further author information
&
Olli KallioniemiInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; ;Science for Life Laboratory, Department of Oncology and Pathology, Karolinska Institutet, Solna, SwedenView further author information
 show all
Pages 3002-3005 | Received 17 Feb 2018, Accepted 12 Mar 2018, Published online: 04 Apr 2018

References

  • Döhner H, Weisdorf DJ, Bloomfield CD. Acute myeloid leukemia. N Engl J Med. 2015;373:1136–1152.
  • Ding L, Ley TJ, Larson DE, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012;481:506–510.
  • Ojamies PN, Kontro M, Edgren H, et al. Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia. Leukemia. 2017;31:1048–1058.
  • Gerlinger M, Rowan AJ, Horswell S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med. 2012;366:883–892.
  • Gundem G, Van Loo P, Kremeyer B, et al. The evolutionary history of lethal metastatic prostate cancer. Nature. 2015;520:353–357.
  • Vanderhoek M, Juckett MB, Perlman SB, et al. Early assessment of treatment response in patients with AML using [(18)F]FLT PET imaging. Leuk Res. 2011;35:310–316.
  • Arimoto MK, Nakamoto Y, Nakatani K, et al. Increased bone marrow uptake of 18F-FDG in leukemia patients: preliminary findings. Springerplus. 2015;4:521.
  • Brierley CK, Morgan EA, Sprague JR, et al. An extreme example of focal bone marrow involvement in acute myeloid leukemia. Am J Hematol. 2013;88:335–336.
  • Garderet L, Labopin M, Gorin NC, et al. Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT). Blood. 2005;105:405–409.
  • Popic V, Salari R, Hajirasouliha I, et al. Fast and scalable inference of multi-sample cancer lineages. Genome Biol. 2015;16:91.
  • Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361:1058–1066.
  • Sperling AS, Gibson CJ, Ebert BL. The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia. Nat Rev Cancer. 2017;17:5–19.
  • Cancer Genome Atlas Research N, Ley TJ, Miller C, et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med. 2013;368:2059–2074.
  • Johansson B, Billstrom R, Kristoffersson U, et al. Deletion of chromosome arm 3p in hematologic malignancies. Leukemia. 1997;11:1207–1213.
  • Osborne MJ, Volpon L, Kornblatt JA, et al. eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition. Proc Natl Acad Sci USA. 2013;110:3877–3882.

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