Advanced search
Publication Cover
Leukemia & Lymphoma Volume 59, 2018 - Issue 12
Submit an article Journal homepage
320
Views
11
CrossRef citations to date
0
Altmetric
Original Article: Clinical

Deferred treatment is a safe and viable option for selected patients with mantle cell lymphoma

Oscar CalzadaDepartment of Hematology and Medical Oncology, Emory University – Winship Cancer Institute, Atlanta, GA, USA; View further author information
,
Jeffrey M. SwitchenkoDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA; View further author information
,
Joseph J. MalyThe Ohio State University – James Comprehensive Cancer Center, Columbus, OH, USA; View further author information
,
Kristie A. BlumThe Ohio State University – James Comprehensive Cancer Center, Columbus, OH, USA; View further author information
,
Natalie GroverLineberger Cancer Center – University of North Carolina, Chapel Hill, NC, USA; View further author information
,
Stephanie MathewsLineberger Cancer Center – University of North Carolina, Chapel Hill, NC, USA; View further author information
,
Steven I. ParkLineberger Cancer Center – University of North Carolina, Chapel Hill, NC, USA; View further author information
,
Max GordonOregon Health Sciences University, Portland, OR, USA; View further author information
,
Alexey DanilovOregon Health Sciences University, Portland, OR, USA; View further author information
,
Narendranath EpperlaDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USAView further author information
,
Timothy S. FenskeDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USAView further author information
,
Mehdi HamadaniDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USAView further author information
,
Christopher R. FlowersDepartment of Hematology and Medical Oncology, Emory University – Winship Cancer Institute, Atlanta, GA, USA; View further author information
&
Jonathon B. CohenDepartment of Hematology and Medical Oncology, Emory University – Winship Cancer Institute, Atlanta, GA, USA; Correspondence[email protected]
View further author information
 show all
Pages 2862-2870 | Received 21 Mar 2017, Accepted 13 Mar 2018, Published online: 18 Jun 2018

References

  • Hoster E, Dreyling M, Klapper W, et al. A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma. Blood. 2008;111:558–565.
  • Budde LE, Guthrie KA, Till BG, et al. Mantle cell lymphoma international prognostic index but not pretransplantation induction regimen predicts survival for patients with mantle-cell lymphoma receiving high-dose therapy and autologous stem-cell transplantation. J Clin Oncol. 2011;29:3023–3029.
  • Cohen JB, Ruppert AS, Heerema NA, et al. Complex karyotype is associated with aggressive disease and shortened progression-free survival in patients with newly diagnosed mantle cell lymphoma. Clin Lymphoma Myeloma Leukemia. 2015;15:278–285.e1.
  • Martin P, Chadburn A, Christos P, et al. Outcome of deferred initial therapy in mantle-cell lymphoma. JCO. 2009;27:1209–1213.
  • Abrisqueta P, Scott DW, Slack GW, et al. Observation as the initial management strategy in patients with mantle cell lymphoma. Ann Oncol. 2017;28:2489–2495.
  • Cohen JB, Han X, Jemal A, et al. Deferred therapy is associated with improved overall survival in patients with newly diagnosed mantle cell lymphoma. Cancer. 2016;122:2356–2363.
  • Determann O, Hoster E, Ott G, et al. Ki-67 predicts outcome in advanced-stage mantle cell lymphoma patients treated with anti-CD20 immunochemotherapy: results from randomized trials of the European MCL Network and the German Low Grade Lymphoma Study Group. Blood. 2008;111:2385–2387.
  • Ambinder AJ, Shenoy PJ, Nastoupil LJ, et al. Using primary site as a predictor of survival in mantle cell lymphoma. Cancer. 2013;119:1570–1577.
  • Orchard J, Garand R, Davis Z, et al. A subset of t(11;14) lymphoma with mantle cell features displays mutated genes and includes patients with good prognosis, nonnodal disease. Blood. 2003;101:4975.
  • Fernàndez V, Salamero O, Espinet B, et al. Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma. Cancer Res. 2010;70:1408.
  • Ondrejka SL, Lai R, Smith SD, et al. Indolent mantle cell leukemia: a clinicopathological variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis. Haematologica. 2011;96:1121
  • Furtado M, Rule S. Indolent mantle cell lymphoma. Haematologica. 2011;96:1086
  • Zelenetz AD, Gordon LI, Wierda WG, et al. Non-Hodgkin's lymphomas, version 4.2014. J Natl Compr Canc Netw. 2014;12:1282–1303.
  • Eskelund CW, Dahl C, Hansen JW, et al. TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy. Blood. 2017;130:1903–1910.
  • Aukema SM, Hoster E, Rosenwald A, et al. Expression of TP53 is associated with the outcome of MCL independent of MIPI and Ki-67 in trials of the European MCL Network. Blood. 2018;131:417–420.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.