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Commentary

Revisiting the role of radiotherapy in Hodgkin lymphoma to augment systemic immunity

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Pages 2519-2520 | Received 03 Apr 2018, Accepted 04 Apr 2018, Published online: 22 Jun 2018

References

  • Kaplan HS. The radical radiotherapy of regionally localized Hodgkin's disease. Radiology. 1962;78:553–561.
  • Demaria S, Ng B, Devitt ML, et al. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int J Radiat Oncol Biol Phys. 2004;58:862–870.
  • Reynders K, Illidge T, Siva S, et al. The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant. Cancer Treatment Rev. 2015;41:503–510.
  • Ansell SM, Lesokhin AM, Borrello I, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015;372:311–319.
  • Wight JC, Hawkes EA, Berlangieri SU, et al. An abscopal effect may augment PD-1inhibition in refractory classical Hodgkin lymphoma. Leuk Lymphoma. 2018;1–3. DOI:10.1080/10428194.2018.1452217.
  • Michot JM, Mazeron R, Dercle L, et al. Abscopal effect in a Hodgkin lymphoma patient treated by an anti-programmed death 1 antibody. Eur J Cancer. 2016;66:91–94.
  • Baues C, Semrau R, Gaipl US, et al. Checkpoint inhibitors and radiation treatment in Hodgkin's lymphoma: new study concepts of the German Hodgkin Study Group. Strahlenther Onkol. 2017;193:95–99.
  • Green MR, Monti S, Rodig SJ, et al. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood. 2010;116:3268–3277.
  • Dovedi SJ, Adlard AL, Lipowska-Bhalla G, et al. Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade. Cancer Res. 2014;74:5458–5468.

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