Advanced search
Publication Cover
Leukemia & Lymphoma Volume 61, 2020 - Issue 2
Submit an article Journal homepage
289
Views
8
CrossRef citations to date
0
Altmetric
Letters to the Editor

Efficacy of imatinib and chemotherapy in a pediatric patient with Philadelphia-like acute lymphoblastic leukemia with Ebf1-Pdgfrb fusion transcript

Francesca FazioHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Walter BarberiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Gianni CazzanigaCentro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy; View further author information
,
Grazia FazioCentro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy; View further author information
,
Monica MessinaHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Irene Della StarzaGIMEMA Foundation, Rome, Italy; View further author information
,
Maria Stefania De ProprisHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Francesca ManciniHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Sara MohamedHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Ilaria Del GiudiceHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Sabina ChiarettiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Maria Luisa MoletiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
,
Anna GuariniDepartment of Molecular Medicine, Sapienza University, Rome, ItalyView further author information
,
Robin FoàHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; View further author information
&
Anna Maria TestiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy; Correspondence[email protected]
View further author information
 show all
Pages 469-472 | Received 18 Jul 2019, Accepted 11 Sep 2019, Published online: 27 Sep 2019

References

  • Boer JM, den Boer ML. BCR-ABL1-like acute lymphoblastic leukaemia: From bench to bedside. Eur J Cancer. 2017;82:203–218.
  • Den Boer ML, van Slegtenhorst M, De Menezes RX, et al. A subtype of childhood acute lymphoblastic leukemia with poor treatment outcome: a genome – wide classification study. Lancet Oncol. 2009;10(2):125–134.
  • Roberts KG, Morin RD, Zhang J, et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell. 2012;22(2):153–166.
  • Roberts KG. The biology of Philadelphia chromosome-like ALL. Best Pract Res Clin Haematol. 2017;30(3):212–221.
  • Chiaretti S, Messina M, Foà R. BCR/ABL1-like acute lymphoblastic leukemia: how to diagnose and treat? Cancer. 2019;125(2):194–204.
  • Conter V, Valsecchi MG, Buldini BP, et al. Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis. Lancet Haematol. 2016;3(2):e80–e86.
  • Chiaretti S, Messina M, Grammatico S, et al. Rapid identification of BCR/ABL1-like acute lymphoblastic leukemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications. Br J Haematol. 2018;181(5):642–652.
  • Jain N, Kathryn GR, Jabbour E, et al. Ph-like acute lymphoblastic leukemia: a high risk subtype in adults. Blood. 2017;129(5):572–581.
  • Golub TR, Barker GF, Lovett M, et al. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell. 1994;77(2):307–316.
  • Ishibashi T, Yaguchi A, Terada K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44(3):177–188.
  • Roberts KG, Li Y, Payne-Turner D, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med. 2014;371(11):1005–1015.
  • Heilmann AM, Schrock AB, He J, et al. Novel PDGFRB fusions in childhood B- and T-acute lymphoblastic leukemia. Leukemia. 2017;31(9):1989–1992.
  • Schwab C, Ryan SL, Chilton L, et al. EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications. Blood. 2016;127(18):2214–2218.
  • Chiaretti S, Messina M, Lauretti A, et al. Prognositc impact of the BCR/ABL1-like signature in adult B-lineage ALL. First analysis of the GIMEMA LAL 1913 Protocol. EmaSphere. 2018;2(S1):400(PS901).
  • Grioni A, Fazio G, Rigamonti S, et al. Simple RNA target capture NGS strategy for fusion genes assessment in the diagnostics of pediatric B-cell acute lymphoblastic leukemia. HemaSphere. 2019;3(3):e250.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.