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Leukemia & Lymphoma Volume 61, 2020 - Issue 2
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Letters to the Editor

Clonally-Related CD5+ CLL/SLL and CD10+ high grade B-cell lymphoma suggests common neoplastic progenitor with branched disease evolution, with therapeutic implications

Priyadarshini KumarHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; ORCID Iconhttp://orcid.org/0000-0001-8945-6917View further author information
ORCID Icon,
Manik UppalWeill Cornell Medical College, New York, NY, USA; View further author information
,
Wenbin XiaoHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Ahmet DoganHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Mikhail RoshalHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Qi GaoHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Umut AyparCytogenetics Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Yanming ZhangCytogenetics Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Maria E. ArcilaHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; ;Molecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Christine MoungMolecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Jinjuan YaoMolecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Khedoudja NafaMolecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Wayne YuMolecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Mustafa H. SyedMolecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; View further author information
,
Jae ParkLeukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; View further author information
,
Anita KumarLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USAView further author information
&
Caleb HoHematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; ;Molecular Diagnostics, Department of Pathology, Memorial Sloan Kettering Cancer Center; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-5448-4635View further author information
ORCID Icon show all
Pages 460-464 | Received 12 Jul 2019, Accepted 23 Sep 2019, Published online: 15 Oct 2019

References

  • Swerdlow SH, Campo E, Harris NL, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon: International Agency for Research on Cancer (IARC); 2017. (Steven H. Swerdlow MEC, MD, PhD; Nancy Lee Harris, MD; Elaine S. Jaffe, MD; Stefani A. Pileri, MD, PhD; Harald Stein, MD; Jurgen Thiele, MD, PhD, editor. World Health Organization Classification of Tumours).
  • Tsimberidou AM, Keating MJ. Richter syndrome: biology, incidence, and therapeutic strategies. Cancer. 2005;103(2):216–228.
  • Fabbri G, Khiabanian H, Holmes AB, et al. Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome. J Exp Med. 2013;210(11):2273–2288.
  • Rossi D, Spina V, Deambrogi C, et al. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation. Blood. 2011;117(12):3391–3401.
  • Chigrinova E, Rinaldi A, Kwee I, et al. Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome. Blood. 2013;122(15):2673–2682.
  • Cheng DT, Mitchell TN, Zehir A, et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based Next-Generation sequencing clinical assay for solid tumor molecular oncology. J Mol Diagn. 2015;17(3):251–264.
  • Arcila ME, Yu W, Syed M, et al. Establishment of Immunoglobulin Heavy (IGH) Chain clonality testing by Next-Generation sequencing for routine characterization of B-Cell and plasma cell neoplasms. J Mol Diagn. 2019;21(2):330–342.
  • Matolcsy A, Chadburn A, Knowles DM. De novo CD5-positive and Richter's syndrome-associated diffuse large B cell lymphomas are genotypically distinct. Am J Pathol. 1995;147(1):207–216.
  • Miyamura K, Osada H, Yamauchi T, et al. Single clonal origin of neoplastic B-cells with different immunoglobulin light chains in a patient with Richter's syndrome. Cancer. 1990;66(1):140–144.
  • Kroft SH, Dawson DB, McKenna RW. Large cell lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma. A flow cytometric analysis of seven cases. Am J Clin Pathol. 2001;115(3):385–395.
  • Woroniecka R, Rymkiewicz G, Grygalewicz B, et al. Cytogenetic and flow cytometry evaluation of Richter syndrome reveals MYC, CDKN2A, IGH alterations with loss of CD52, CD62L and increase of CD71 antigen expression as the most frequent recurrent abnormalities. Am J Clin Pathol. 2015;143(1):25–35.
  • Kharfan-Dabaja MA, Kumar A, Hamadani M, et al. Clinical practice recommendations for use of allogeneic hematopoietic cell transplantation in chronic lymphocytic leukemia on behalf of the guidelines committee of the american society for blood and marrow transplantation. Biol Blood Marrow Tr. 2016;22(12):2117–2125.
  • Nguyen L, Papenhausen P, Shao H. The role of c-MYC in B-cell lymphomas: Diagnostic and molecular aspects. Genes (Basel). 2017;8(4):116.
  • Delgado J, Bea S, Valdes-Mas R, et al. Linear and branching progression of chronic lymphocytic leukemia (CLL) under PI3K inhibition (PI3Ki). Blood. 2017;130:3000.
  • Woyach JA, Furman RR, Liu TM, et al. Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. N Engl J Med. 2014;370(24):2286–2294.
  • Burger JA, Landau DA, Taylor-Weiner A, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nat Commun. 2016;7(1):11589.

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