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Original Articles

Improved post-ASCT survival of relapsed/refractory classical Hodgkin lymphoma patients in the era of novel agents

ORCID Icon, , , , , , , , , , & show all
Pages 813-820 | Received 13 Jul 2021, Accepted 26 Oct 2021, Published online: 15 Nov 2021

  • Radford J, Illidge T, Counsell N, et al. Results of a trial of PET-directed therapy for early-stage hodgkin's lymphoma. N Engl J Med. 2015;372(17):1598–1607.
  • André MPE, Girinsky T, Federico M, et al. Early positron emission tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial. J Clin Oncol. 2017;35(16):1786–1794.
  • Engert A, Plütschow A, Eich HT, et al. Reduced treatment intensity in patients with Early-Stage hodgkin's lymphoma. N Engl J Med. 2010;363(7):640–652.
  • Johnson P, Federico M, Kirkwood A, et al. Adapted treatment guided by interim PET-CT scan in advanced hodgkin's lymphoma. N Engl J Med. 2016;374(25):2419–2429.
  • Press OW, Li H, Schöder H, et al. US intergroup trial of Response-Adapted therapy for stage III to IV hodgkin lymphoma using early interim Fluorodeoxyglucose-Positron emission tomography imaging: Southwest oncology group S0816. J Clin Oncol. 2016;34(17):2020–2027.
  • Schmitz N, Pfistner B, Sextro M, et al. Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haemopoietic stem-cell transplantation for relapsed chemosensitive hodgkin's disease: a randomised trial. The Lancet. 2002;359(9323):2065–2071.
  • Josting A, Rudolph C, Mapara M, et al. Cologne high-dose sequential chemotherapy in relapsed and refractory hodgkin lymphoma: results of a large multicenter study of the german hodgkin lymphoma study group (GHSG). Ann Oncol. 2005;16(1):116–123.
  • Arai S, Fanale M, DeVos S, et al. Defining a hodgkin lymphoma population for novel therapeutics after relapse from autologous hematopoietic cell transplant. Leuk Lymphoma. 2013;54(11):2531–2533.
  • Moskowitz AJ, Perales M-A, Kewalramani T, et al. Outcomes for patients who fail high dose chemoradiotherapy and autologous stem cell rescue for relapsed and primary refractory hodgkin lymphoma. Br J Haematol. 2009;146(2):158–163.
  • Milgrom SA, Jauhari S, Plastaras JP, et al. A multi-institutional analysis of peritransplantation radiotherapy in patients with relapsed/refractory hodgkin lymphoma undergoing autologous stem cell transplantation. Cancer. 2017;123(8):1363–1371.
  • Chen R, Zinzani PL, Lee HJ, et al. Pembrolizumab in relapsed or refractory hodgkin lymphoma: 2-year follow-up of KEYNOTE-087. Blood. 2019;134(14):1144–1153.
  • Armand P, Engert A, Younes A, et al. Nivolumab for relapsed/refractory classic hodgkin lymphoma after failure of autologous hematopoietic cell transplantation: Extended Follow-Up of the multicohort Single-Arm phase II CheckMate 205 trial. J Clin Oncol. 2018;36(14):1428–1439.
  • Gopal AK, Chen R, Smith SE, et al. Durable remissions in a pivotal phase 2 study of brentuximab vedotin in relapsed or refractory hodgkin lymphoma. Blood. 2015;125(8):1236–1243.
  • LaCasce AS, Bociek RG, Sawas A, et al. Brentuximab vedotin plus bendamustine: a highly active first salvage regimen for relapsed or refractory hodgkin lymphoma. Blood. 2018;132(1):40–48.
  • Herrera AF, Chen RW, Palmer J, et al. PET-Adapted nivolumab or nivolumab plus ICE as first salvage therapy in relapsed or refractory hodgkin lymphoma. Blood. 2019;134(Supplement_1):239–239.
  • Herrera AF, Moskowitz AJ, Bartlett NL, et al. Interim results of brentuximab vedotin in combination with nivolumab in patients with relapsed or refractory hodgkin lymphoma. Blood. 2018;131(11):1183–1194.
  • Moskowitz CH, Matasar MJ, Zelenetz AD, et al. Normalization of pre-ASCT, FDG-PET imaging with second-line, non-cross-resistant, chemotherapy programs improves event-free survival in patients with hodgkin lymphoma. Blood. 2012;119(7):1665–1670.
  • Moskowitz AJ, Shah G, Schöder H, et al. Phase II study of pembrolizumab plus GVD as Second-Line therapy for relapsed or refractory classical hodgkin lymphoma. Blood. 2020;136(Supplement 1):17–18.
  • Cheson BD, Pfistner B, Juweid ME, et al.; International Harmonization Project on Lymphoma. Revised response criteria for malignant lymphoma. J Clin Oncol. 2007;25(5):579–586.
  • Cheson BD, Ansell S, Schwartz L, et al. Refinement of the lugano classification lymphoma response criteria in the era of immunomodulatory therapy. Blood. 2016;128(21):2489–2496.
  • Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for Non-Hodgkin's lymphomas. NCI Sponsored International Working GroupJ Clin Oncol. 1999;17(4):1244–1244.
  • Bair SM, Strelec L, Nagle SJ, et al. Outcomes of patients with relapsed/refractory hodgkin lymphoma progressing after autologous stem cell transplant in the current era of novel therapeutics: a retrospective analysis. Am J Hematol. 2017;92(9):879–884.
  • Badar T, Epperla N, Szabo A, et al. Trends in postrelapse survival in classic hodgkin lymphoma patients after experiencing therapy failure following auto-HCT. Blood Adv. 2020;4(1):47–54.
  • Juweid ME, Cheson BD. Positron-Emission tomography and assessment of cancer therapy. N Engl J Med. 2006;354(5):496–507.
  • Bar Ad V, Paltiel O, Glatstein E. Radiotherapy for early-stage hodgkin's lymphoma: a 21st century perspective and review of multiple randomized clinical trials. Int J Radiat Oncol Biol Phys. 2008;72(5):1472–1479.
  • Rashidi A, Ebadi M, Cashen AF. Allogeneic hematopoietic stem cell transplantation in hodgkin lymphoma: a systematic review and Meta-analysis. Bone Marrow Transplant. 2016;51(4):521–528.
  • Cheson BD, Fisher RI, Barrington SF, et al.; United Kingdom National Cancer Research Institute. Recommendations for initial evaluation, staging, and response assessment of hodgkin and non-Hodgkin lymphoma: the lugano classification. J Clin Oncol. 2014;32(27):3059–3068.
  • Juweid ME, Wiseman GA, Vose JM, et al. Response assessment of aggressive non-Hodgkin's lymphoma by integrated international workshop criteria and fluorine-18-fluorodeoxyglucose positron emission tomography. J Clin Oncol. 2005;23(21):4652–4661.
  • Advani RH, Moskowitz AJ, Bartlett NL, et al. Brentuximab vedotin in combination with nivolumab in relapsed or refractory hodgkin lymphoma: 3-year study results. Blood. 2021;138(6):427–438.,
  • Moskowitz AJ, Shah G, Schöder H, et al. Phase II trial of pembrolizumab plus gemcitabine, vinorelbine, and liposomal doxorubicin as Second-Line therapy for relapsed or refractory classical hodgkin lymphoma. J Clin Oncol. 2021;39(28):3109–3117.

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