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Leukemia & Lymphoma Volume 63, 2022 - Issue 9
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Letters to the Editor

Apparent coexistence of ETV6::RUNX1 and KMT2A::MLLT3 fusions due to a nonproductive KMT2A rearrangement in B-ALL

Marie-France Gagnona Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USAView further author information
,
James B. Smadbeckb Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USAView further author information
,
Neeraj Sharmaa Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USAView further author information
,
Patrick R. Blackburnc Department of Pathology, St. Jude Children’s Hospital, Memphis, TN, USAView further author information
,
Jonna Demasi Benevidesa Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USAView further author information
,
Yassmine M. N. Akkarid Cytogenetics and Molecular Pathology, Legacy Health, Portland, OR, USAView further author information
,
Jennifer J. Jaroscake Division of Pediatric Hematology-Oncology, College of Medicine, Medical University of South Carolina, Charleston, SC, USAView further author information
,
Iya Znoykof Department of Pathology and Laboratory Medicine, Division of Cytogenetics and Genomics, Medical University of South Carolina, Charleston, SC, USAView further author information
,
Daynna J. Wolfff Department of Pathology and Laboratory Medicine, Division of Cytogenetics and Genomics, Medical University of South Carolina, Charleston, SC, USAView further author information
,
Cynthia A. Schandlf Department of Pathology and Laboratory Medicine, Division of Cytogenetics and Genomics, Medical University of South Carolina, Charleston, SC, USAView further author information
,
Reid Meyera Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USAView further author information
,
Patricia T. Greippa Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA;g Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USAView further author information
,
Xinjie Xua Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA;g Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USAView further author information
,
Nicole L. Hoppmana Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USAView further author information
,
Rhett P. Ketterlinga Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA;g Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USAORCID Iconhttps://orcid.org/0000-0001-6479-7897View further author information
ORCID Icon,
Jess F. Petersona Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA;g Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USAView further author information
&
Linda B. Baughna Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA;g Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5229-4897View further author information
ORCID Icon show all
Pages 2243-2246 | Received 16 Feb 2022, Accepted 02 Apr 2022, Published online: 04 May 2022

References

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  • Hiemenz MC, Chen W, Winick N, et al. Coexistence of t(12;21)(p13;q22)/ETV6-RUNX1 and 11q23/MLL rearrangement in B acute lymphoblastic leukemia: a case report and review of the literature. J Assoc Genet Technol. 2011;37(4):213–215.
  • Li H. Aligning sequence reads, clone sequences and assembly contigs with BWA-MEM: arXiv; 2013. Available from: https://arxiv.org/abs/1303.3997
  • Gaitatzes A, Johnson SH, Smadbeck JB, et al. Genome U-Plot: a whole genome visualization. Bioinformatics. 2018;34(10):1629–1634.
  • Zhou X, Edmonson MN, Wilkinson MR, et al. Exploring genomic alteration in pediatric cancer using ProteinPaint. Nat Genet. 2016;48(1):4–6.
  • Marschalek R. Systematic classification of mixed-lineage leukemia fusion partners predicts additional cancer pathways. Ann Lab Med. 2016;36(2):85–100.

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