Adolescents and young adults (AYA) with acute myeloid leukemia (AML): real-world long-term results and age-specific outcomes

References

• Webster JA, Pratz KW. Acute myeloid leukemia in the elderly: therapeutic options and choice. Leuk Lymphoma. 2018;59(2):274–287.
   PubMed Web of Science ®Google Scholar
• Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–447.
   PubMed Web of Science ®Google Scholar
• Creutzig U, Buchner T, Sauerland MC, et al. Significance of age in acute myeloid leukemia patients younger than 30 years: a common analysis of the pediatric trials AML-BFM 93/98 and the adult trials AMLCG 92/99 and AMLSG HD93/98A. Cancer. 2008;112(3):562–571.
   PubMed Web of Science ®Google Scholar
• Rasche M, Zimmermann M, Borschel L, et al. Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012. Leukemia. 2018;32(10):2167–2177.
   PubMed Web of Science ®Google Scholar
• Ampatzidou M, Kelaidi C, Dworzak MN, et al. Adolescents and young adults with acute lymphoblastic leukemia and acute myeloid leukemia. memo. 2018;11(1):47–53.
   Google Scholar
• Pemmaraju N, Kantarjian H, Ravandi F, et al. Patient characteristics and outcomes in adolescents and young adults (AYA) With acute myeloid leukemia (AML). Clin Lymphoma Myeloma Leuk. 2016;16(4):213–222 e2.
   PubMed Web of Science ®Google Scholar
• McGowan-Jordan JS, Schmid M. An international system for human cytogenomic nomenclature. Simons A, City: Basel, Publisher: S Karger AG, 2016;2016: 84–91.
   Google Scholar
• Burnett A, Stone R. AML: New drugs but new challenges. Clin Lymphoma Myeloma Leuk. 2020;20(6):341–350.
   PubMed Web of Science ®Google Scholar
• Polychronopoulou S, Baka M, Servitzoglou M, et al. Treatment and clinical results in childhood AML in Greece. memo. 2014;7(1):50–55.
   Google Scholar
• Nasir SS, Giri S, Nunnery S, et al. Outcome of adolescents and young adults compared With pediatric patients With acute myeloid and promyelocytic leukemia. Clin Lymphoma Myeloma Leuk. 2017;17(2):126–132 e1.
   PubMed Web of Science ®Google Scholar
• Bolouri H, Farrar JE, Triche T, Jr., et al. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2018;24(1):103–112.
   PubMed Web of Science ®Google Scholar
• Creutzig U, Zimmermann M, Reinhardt D, et al. Changes in cytogenetics and molecular genetics in acute myeloid leukemia from childhood to adult age groups. Cancer. 2016;122(24):3821–3830.
   PubMed Web of Science ®Google Scholar
• Fornerod M, Ma J, Noort S, for St. Jude Children's Research Hospital Study Group (SJCRH), et al. Integrative genomic analysis of pediatric myeloid-related acute leukemias identifies novel subtypes and prognostic indicators. Blood Cancer Discov. 2021;2(6):586–599.
   PubMedGoogle Scholar
• Lalayanni C, Gavriilaki E, Athanasiadou A, et al. Secondary acute myeloid leukemia (sAML): similarly dismal outcomes of AML After an antecedent hematologic disorder and therapy related AML. Clin Lymphoma Myeloma Leuk. 2022 Apr;22(4):e233–e240. doi: 10.1016/j.clml.2021.09.019. Epub 2021 Oct 1.
   Google Scholar
• Schoch C, Kern W, Schnittger S, et al. The influence of age on prognosis of de novo acute myeloid leukemia differs according to cytogenetic subgroups. Haematologica. 2004;89(9):1082–1090.
   PubMed Web of Science ®Google Scholar
• Yoo KH, Kim HJ, Min YH, et al. Age and remission induction therapy for acute myeloid leukemia: An analysis of data from the korean acute myeloid leukemia registry. PLoS One. 2021;16(5):e0251011.
   PubMed Web of Science ®Google Scholar
• Hjort Jakobsen L, Stidsholt Roug A, Kiesbye OA, et al. Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a danish population-based study. Br J Haematol. 2021; 193(3):482–487.
   PubMed Web of Science ®Google Scholar
• August KJ, Aplenc R, Sung L, et al. Adolescents and young adults (AYA) with acute myeloid leukemia (AML) have increased Treatment-Related mortality with similar outcomes – a report from the children's oncology group trials AAML03P1 and AAML0531. Blood. 2014;124(21):3672–3672.
   PubMed Web of Science ®Google Scholar
• Woods WG, Franklin AR, Alonzo TA, et al. Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials. Cancer. 2013;119(23):4170–4179.
   PubMed Web of Science ®Google Scholar
• Koreth J, Schlenk R, Kopecky KJ, et al. Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: systematic review and Meta-analysis of prospective clinical trials. JAMA. 2009;301(22):2349–2361.
   PubMed Web of Science ®Google Scholar
• Li D, Wang L, Zhu H, et al. Efficacy of allogeneic hematopoietic stem cell transplantation in Intermediate-Risk acute myeloid leukemia adult patients in first complete remission: a Meta-Analysis of prospective studies. PLoS One. 2015;10(7):e0132620.
   PubMed Web of Science ®Google Scholar
• Lee CJ, Kim S, Tecca HR, et al. Late effects after ablative allogeneic stem cell transplantation for adolescent and young adult acute myeloid leukemia. Blood Adv. 2020;4(6):983–992.
   PubMed Web of Science ®Google Scholar
• Tomizawa D, Tanaka S, Kondo T, et al. Allogeneic hematopoietic stem cell transplantation for adolescents and young adults with acute myeloid leukemia. Biol Blood Marrow Transplant. 2017;23(9):1515–1522.
   PubMed Web of Science ®Google Scholar
• Stone RM, Mandrekar SJ, Sanford BL, et al. Midostaurin plus chemotherapy for acute myeloid leukemia with a FLT3 mutation. N Engl J Med. 2017;377(5):454–464.
   PubMed Web of Science ®Google Scholar
• Yanada M. The evolving concept of indications for allogeneic hematopoietic cell transplantation during first complete remission of acute myeloid leukemia. Bone Marrow Transplant. 2021;56(6):1257–1265.
   PubMed Web of Science ®Google Scholar
• O'Dwyer K, Freyer DR, Horan JT. Treatment strategies for adolescent and young adult patients with acute myeloid leukemia. Blood. 2018;132(4):362–368.
   PubMed Web of Science ®Google Scholar
• Wolfson J, Sun CL, Wyatt L, et al. Adolescents and young adults with acute lymphoblastic leukemia and acute myeloid leukemia: Impact of care at specialized cancer centers on survival outcome. Cancer Epidemiol Biomarkers Prev. 2017; 26(3):312–320.
   PubMed Web of Science ®Google Scholar