Advanced search
Publication Cover
Leukemia & Lymphoma Volume 64, 2023 - Issue 2
Submit an article Journal homepage
133
Views
0
CrossRef citations to date
0
Altmetric
Letters to the Editor

Organ toxicities associated with chimeric antigen receptor T-cell therapy

Mary McGanna Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7302-6573
ORCID Icon,
Kelly J. Gaffneya Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USA
,
James A. Davisa Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USAORCID Iconhttps://orcid.org/0000-0001-7978-1652
ORCID Icon,
Deidra Smitha Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USA
&
Hamza Hashmib Department of Hematology and Bone Marrow Transplantation, Medical University of South Carolina, Charleston, SC, USA
Pages 491-494 | Received 09 Aug 2022, Accepted 26 Oct 2022, Published online: 23 Nov 2022

References

  • Zhang X, Zhu L, Zhang H, et al. CAR-T cell therapy in hematological malignancies: current opportunities and challenges. Front Immunol. 2022;13:927153.
  • Lee DW, Santomasso BD, Locke FL, et al. ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells. Biol Blood Marrow Transplant. 2019;25(4):625–638.
  • Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012;120(4):c179–c184.
  • Common Terminology Criteria for Adverse Events (CTCAE) Version 5; 2021. US Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Washington, DC.
  • Lefebvre B, Kang Y, Smith AM, et al. Cardiovascular effects of CAR T cell therapy: a retrospective study. JACC CardioOncol. 2020;2(2):193–203.
  • Steiner RE, Banchs J, Koutroumpakis E, et al. Cardiovascular events in patients treated with chimeric antigen receptor T-cell therapy for aggressive B-cell lymphoma. Haematologica. 2021;107(7):1555–1566.
  • Goldman A, Maor E, Bomze D, et al. Adverse cardiovascular and pulmonary events associated with chimeric antigen receptor T-cell therapy. J Am Coll Cardiol. 2021;78(18):1800–1813.
  • Wudhikarn K, Pennisi M, Garcia-Recio M, et al. DLBCL patients treated with CD19 CAR T cells experience a high burden of organ toxicities but low non-relapse mortality. Blood Adv. 2020;4(13):3024–3033.
  • Gutgarts V, Jain T, Zheng J, et al. Acute kidney injury after CAR-T cell therapy: low incidence and rapid recovery. Biol Blood Marrow Transplant. 2020;26(6):1071–1076.
  • Gupta S, Seethapathy H, Strohbehn IA, et al. Acute kidney injury and electrolyte abnormalities after chimeric antigen receptor T-cell therapy for diffuse large B-cell lymphoma. Am J Kidney Dis. 2020;76(1):63–71.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.